Aashi Arora MCB250_Discussion2_SP24

Biomaterial question: Give a brief and clear answer, please a. Briefly describe the structural differences between the three major types of biomaterials,  including their chemical structure, bonding characteristics, crystal structures, etc.  b. Explain briefly the working principle and the information provided by the spectroscopic  and chromatographic characterization techniques . Give an example to each of  them.

offset=next&assignment ProblemID=218423920 Which of the following statements is FALSE regarding proteins? The three-dimensional shape of a protein is critical for the functioning of that protein. O There is a link between improperly folded proteins and disease in both mad cow disease and Alzheimer's disease. Alzheimer's disease causes proteins in the brain to become improperly folded. O High heat and a change in pH can denature a protein. Submit Part C Request Answer Why does the story in the video start in Colombia? <

16 water's cohesive property allows water to transport dissolved nutrients against gravity   true or false

Time remaining: 00:08:55 Chemistry Consider a peptide with the following amino acid sequence: H2N-ASENHLDGCPYTKSRG-COOH Analyze the predominate protonation state and thus dominate charge (+1, 0, -1) of the residues in this peptide at pH 3, 6, and 10 by filling in the table below, identifying the relevant pKa appropriate for each residue. (Note that choice of pKa and its. application will be graded independently; e.g., if you can choose the wrong pKa but apply it correctly, you will lose points only for the pKa.) AA Residue pKa Charge pH 3 Charge pH 6 Charge pH 10 A         S         E         N         H         L         D         G         C         P         Y         T         K         S         R         G

10, 11 please answer all give the significance/role/effect of the reagent/condition in the isolation or analysis of a biomolecule. limit answers to two short sentences

Question for protein crystallography- 1. While performing a routine protein crystallization screening, you observe that one of your well drops has doubled in size compared to the remaining wells. Note: the drop in question was set up by taking 1 µL of the protein solution (10 mg/mL LDH in 20 mM TRIS pH 7.5, 0.5 M NaCl and 10% PEG 4000K) and adding it to 1 µL of the crystallization solution (10% PEG 4000K, 50 mM NaCl and 20 mM TRIS pH 8.0). Why did this drop grow larger in size compared to when you initially set it up?

3-54   What chemical reaction involving the cysteine molecule produces a                 disulfide bond?

1-39. Classify each of the molecules in problem 1-37 as D-enantiomer or an L-enantiomer

384 Peptides & X-ray/NMR Methods Q4.2- Describe one advantage and one disadvantage of trying to solve molecular protein structures by 1) X-ray crystallography and by 2) Nuclear Magnetic Resonance (NMR) spectroscopy.

Further discussion questions: a) What is the wavelength of UV light with maximal absorbance by purified protein? Which amino acid(s) in protein has/ have the highest absorbance at this wavelength? b) Name and briefly describe two methods (other than UV absorbance) to detect proteins in a sample.

Ee.35. How do you make a 10x solution of 1M dextrose? What should be the volume and how many grams. (show your work)

20. The dissociation constant of protein Z for ligand Y is: 10 micromolar. What fraction of the ligand is bound at ligand concentration = 5 micromolar?

PROBLEM 3-1 Sentence InterpretationWhen scientists submit papers for publication, they often dread the re-sponse of reviewers. Here are four sentences that could have been writ-ten in different structural arrangements by reviewers to deliver the same news. Which statement is the one most likely resulting in the paper being accepted, and which is most likely the one resulting in rejection? Explain why.1. Overall, although this manuscript is of interest for structural biologists, a more detailed analysis of ABC should be provided. 2. Although a more detailed analysis of ABC should be provided, this manuscript is of interest for structural biologists.3. This manuscript is of interest for structural biologists, but a more detailed analysis of ABC should be provided.4. A more detailed analysis of ABC should be provided, but overall, this manuscript is of interest for structural biologists. PROBLEM 3-2 Word Placement and Flow Rewrite the following paragraph. Place words such that the reader…

384 Functional Classes of Proteins Q4.3- For each of the five major protein types in eukaryotic cells 1) provide a specific example of a protein in each class, 2) describe its primary function, and 3) identify cellular locations where you would find this specific protein (nucleus, cytosol, membranes).

85. If a Cys-Cys disulfide bond is required in a structure, which amino acid could substitute for Cys? Lys None of these answers. Arg His Met

Drop-down options: a) 1, 2, 3, 4, 5, 6 b) no carbon label, the methyl carbon labeled, or the carbonyl carbon labeled c) carbon-1, carbon-2, or neither carbon-1 carbon-2 d) will not be incorporated, will be incorporated at every even-numbered carbon, or will be incorporated at every odd-numbered carbon

64. According to lecture, Orrorin tugenensis dates to approximately   3 mya.   2 mya.   16 mya.   6 mya.   1 mya.

71 please match the 5 ,,,same choices for the 5 compounds