Alzheimer 's : An Irreversible Progressive Brain Disease

Alzheimer’s disease has been around since 1901; a German psychiatrist Alois Alzheimer was the first man to identify and follow a case that is now known as Alzheimer’s disease. Alzheimer’s disease is involved in synaptic deterioration and neuronal cell death, and causes degeneration in the hippocampus and amyloid deposition in blood vessels, ultimately cell death is the cause of the disease. There are various ways that someone can acquire the Alzheimer’s, a few include; family history, obesity, and Down syndrome. Some symptoms of the disease are, memory loss, difficulty completing familiar daily tasks, confusion with

The disease stem cells could fix is called Alzheimer’s Disease (AD). The reason I chose this topic is because I have seen first hand how badly someone who suffers from Alzheimer’s Disease is affected in their daily lives. This disease completely takes over their lives and they turn into a completely different person who can hardly function. AD is very tough on the loved ones of the person suffering from it because that person, most of the time has no idea what is going on or who their loved ones are. The memories for people with AD is completely gone and even the simplest tasks such as remembering to use the bathroom becomes difficult. The way stem cells could be feasible is because stem cell-based therapies could potentially treat

On November 26th 1901, Alois Alzheimer, an assistant physician at the psychiatric institution in Frankfurt met Auguste D, aged 51 (Berrios , 2004). After talking to her and carrying out the preliminary diagnostics, the physicist realized during talking to her that his patient was giving different answers to the same questions. She also often stopped mid-sentence as if she had forgotten what she was going to say. She seemed confused and anxious. When she died, Alzheimer received her brain for analysis. When he was inspecting the brain, he came to notice the neurons had thick, strongly staining fibrils. Moreover, the cortex was full of plaques of unknown composition. Auguste D’s brain

Alzheimer’s is a disease in the brain that affects a person’s memory, thinking, and behavior. It is the most common form of dementia and is common in adults older than 65. More than five million Americans are being affected by Alzheimer’s at this moment. Alzheimer’s comes in three stages; early, middle, and advanced. The disease is caused by the shrinking of the brain due to many risk factors and genetics.

Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health

Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.

Alzheimer’s disease is the progressive loss of memory and mental functions. The disease affects memory, thought control, language, and other cognitive functions. The disease typically appears with old age and is often found age 60. Alzheimer’s causes the brain to develop clumps and tangles fibers in the brain tissue along with the loss of neuron connections. Throughout the brain, proteins are abnormally distributed and they form tangled bundles of fibers and amyloid plaques. Some neurons fail to function properly and lose their connections, which are necessary for the transmission of messages to the body. The hippocampus is the key brain structure in the formation of memories and often experiences the first signs of damage.

Additional signs and symptoms may affect areas of attention, learning, perceptual abilities, reasoning, language and communication, behavior and social thinking, and even feeding and swallowing. These may include episodic memory deficits, being easily distracted, difficulty planning or focusing on a task, inability to recognize familiar people, word-finding difficulties, troubles following simple tasks, inappropriate behavior, lack of motivation, repeating themselves in conversation, forgetting to eat, and many others signs (Dementia: Signs and Symptoms,

- Lost keys, an overlooked name, requiring an additional minute to recall where you stopped your auto. No doubt we 're talking average absentmindedness or simply ordinary age-related changes, not Alzheimer 's ailment. In any case, when you start battling with errands that have dependably been simple (e.g., abruptly not having the capacity to adjust the checkbook) that is more reason for concernsaid by Nancy Udelson. Despite the way that 5.1 million individuals age 65 and more seasoned are as of now influenced by Alzheimer 's, it is not a "typical" some portion of maturing (however the danger rises with age). It is a dynamic issue that assaults the cerebrum 's nerve cells, clarifies Ditty Steinberg, the official VP of the Alzheimer 's Establishment of America. The brains of individuals who have Alzheimer 's are stopped up with injuries that conform to the outside of neurons, eventually annihilating these mind cells. As the person born after WW2 populace gets more established, the rate of Alzheimer 's is anticipated to blast, influencing upwards of 16 million individuals by 2050, unless therapeutic achievements distinguish approaches to forestall or all the more viably treat the illness. In the event that you have relatives who have experienced Alzheimer 's, you may think about whether you 're at higher danger, however just the "early onset" type of the malady (which influences individuals more youthful than 65 and records for under 5 percent of all cases)

Even though Alzheimer 's is being researched, it was not a commonly known disease and many aspects of it remain intangible. In 1901 Auguste D. family brought her to Dr. Alzheimer’s after noticing Auguste problem with memory, impaired comprehension, and unpredictable behavior. Dr. Alzheimer treated Auguste till her death in 1906. He performed an autopsy on her brain and discovered dramatic shrinkage of the cerebral cortex, atrophied brain cells, fatty deposits in blood vessels, neurofibrillary tangles and senile plaques. Plaques and tangles in the brain are two of the main features of Alzheimer’s disease. The third is the loss of connections between neurons in the brain. (https://www.nia.nih.gov/.../alzheimers_disease_fact_sheet_

“Alzheimer’s From A New Angle: A radical new approach to treating the fearful disease is showing promise” by Alice Park, an article found in the February 22/29, 2016 issue of TIME magazine, delves into encouraging new research being conducted to find a cure for Alzheimer’s disease, a progressive neurodegenerative condition that destroys the brain. Dr. Frank Longo, from the Department of Neurology and Neurological Sciences at Stanford University, School of Medicine, is leading the charge. This disease was discovered over 110 years ago by a German physician named, Alois Alzheimer. For so many years now, researchers have focused solely on treating/stopping Alzheimer’s once its devastation has already begun. In the last seven years, over

I choose this topic because Alzheimer is a disease, which affects the brain. It mainly occurs in seniors. There is no existing cure for Alzheimer 's, but treatments for symptoms are presented and research continues. However, recent Alzheimer 's treatments cannot discontinue Alzheimer’s from succeeding, but they can for the time being slow the deterioration of dementia symptoms and improve quality of life for those with Alzheimer 's.

In 1906, Dr. Alois Alzheimer saw differences in the brain of a woman that passed away from a bizarre illness in the brain. Before she died she experienced loss of memory, had trouble speaking, and unpredictable behavior. When Dr. Alois Alzheimer examined her brain after death, he noticed that there were abnormal clumps, which are now known as amyloid plaques, and tangled bundles of fibers known as neurofibrillary tangles. While symptoms start to appear after the age of 60, up to 5.1 million Americans may have the disease today.

Alzheimer’s disease is a type of dementia that gradually destroys brain cells, affecting a person’s memory and their ability to learn, make judgments, communicate and carry out basic daily activities. The disease is a progressive degenerative disease of the brain. It was first described by the German neuropathologist Alois Alzheimer in 1905 (Selkoe, 2016). The average life expectancy of an Alzheimers patient is between five and ten years, but some patients today have live for up to 15 years after the diagnosis due to improvements in care and medical treatments. The cause of Alzheimer 's has not yet been discovered and it also not possible to confirm a person has Alzheimer 's until their autopsy following death (Park, 2016).

Alzheimer’s disease is a common neurodegenerative disease. It is the most common form of dementia which is a general term for memory loss and other intellectual abilities serious enough to interfere with daily life (Alzheimer’s Disease & Dementia). Dementia and Alzheimer’s have been around for centuries, but Alzheimer’s disease wasn’t first described until 1906 by Dr. Aloysius Alzheimer. In the past, there was a stigma for elderly people with the disease. People with dementia and Alzheimer’s were seen as a burden on society. Society has only recently accepted and cared for people with the disorder because more information is known about the disease. There wasn’t much treatment in the past accept for locking those away in institutions or just being kept hidden by family members (Batsch). There are now treatments and research being done for dementia and Alzheimer’s, but no cure remains and many individuals still suffer from the disease. Future treatments for the disease include taking aim at significant aspects of the disease like fighting beta-amyloid plaques, recruiting the immune system, reducing brain cell inflammation, and studying the heart-head connection (Alzheimer’s Treatments: What’s on the Horizon?). There are other ways to possibly treat the disease in the future as well. Hopefully from looking at the history of the disease, how the disease affects the brain and body, and future treatments, Alzheimer’s disease and dementia will be a thing of the past.