Diabetic Biological Variation – Rough Draft
Diabetes is a complex disease which bonds together evolution and environmental factors and creates many health issues for humans. Diabetes (mellitus) is classified into three groups of metabolic diseases that involves high blood sugar (glucose) and it can occur in different ways depending on circumstances. Type 2 diabetes occurs when cells do not function correctly, and evidently the cells do not properly respond to insulin. Type 1 diabetes involves the body’s inadequate production of insulin, which is commonly referred to as insulin-dependent diabetes. What are the links between evolution, the environment and a staggering number of people diagnosed with diabetes?
The American Diabetes
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These molecules can cause insulin deficiencies more often in various populations compared to others. Leading research to the idea that diabetes evolved during the processes of Evolution. The newly introduced genetic variation affecting diabetes is thought to have occurred 2,000-12,000 years ago. Individuals with the newly discovered variant have a more frequent rate of fasting levels of blood glucose, compared to those who inherits the traditional glucose regulating gene (Conger, 2011).
These findings insist on the idea that our ancestors evolved to be scavengers and gatherers because it was the only way to find nutrients. Early humans were required to search for food. Conditions required them to evolve in a way that the body stores energy, so when resources became scarce, they stayed healthy and could contribute to their community efficiently. Obtaining the ability to store energy in order for humans stay healthy was an extremely important factor. After our ancestors migrated out of East Africa, they evolved to wonder and scavenge for food. Now, humans are able to live comfortably in a single location. Compared to our ancestors constantly moving looking for food and shelter. (Jurmain et al. 350-351).
Agriculture has made it so food is extremely easy to retain. Current human diets and metabolism are extremely different from that of our ancestors. Sheau Yu Hsu, PhD, stated “These studies are fascinating
Matthews, David. Diabetes. Oxford: Oxford University Press, 2008. eBook Collection (EBSCOhost). Web. 24 Oct. 2013.
Diabetes, Diabetes Mellitus, is a chronic illness this means that it has no cure and the symptoms persist over a long period of time. This illness is a result of an imbalance of hormones, insulin, produced in the pancreas. Insulin plays an important role in how the body uses food. Insulin enables the cells in the bloodstream to absorb and use glucose for fuel. If the pancreas produces too little or no insulin or if the insulin doesn’t work properly the person may become diabetic. Therefore, diabetics are not able to properly convert food into fuels needed by the body to function, which can seriously lead to physical consequences.
the evolutionary process of humans and their nutritional requirements point to the clear fact that while our nutrition has radically changed since Paleolithic times, our biology really
An overview of the proposed sequences of the key pathological features of type 2 diabetes is provided by Dr. Jack Leahy from the University of Vermont College Of Medicine. In his article he addresses the need for continued genetic research since little discovery has been made in this area. He also explains the known environmental causes such as sedentary lifestyles and high fat diets that contribute to type 2 diabetes, changes in lifestyle practices would reduce the incidence of this disease but this is not a practical solution. The best solution according to Dr. Leahy lays in understanding the
Diabetes has become a widespread epidemic, primarily because of the increasing prevalence and incidence of type 2 diabetes. Diabetes is an endocrine disease in which the body has either a shortage of insulin or a decrease ability to use insulin or both. Insulin is a hormone that allows glucose to enter the cells and be converted into energy. Diabetes can be characterized as a prevailing, incapacitating, and deadly disease. There are a number of risk factors that increase a person’s tendency toward developing type II diabetes. Modifiable risk factors include obesity, physical inactivity and poor dietary habits are just a few. The
Diabetes is a disorder that is formed by high blood glucose. Diabetes is the seventh leading cause for death in the United States. It occurs most often in adults, but it’s one of the most chronic disorders in children. Individuals suffering from hyperglycemia have low production of insulin. American Diabetes Association is trying to prevent and cure diabetes and improve the lives of all people affected by diabetes.
Type 2 diabetes results from a combination of genetic and environmental factors (Diabetesaustralia.com.au, (2013). Although diabetes may run in the family, the risk is greatly increased when associated with lifestyle factors such as not enough physical activity, unhealthy diet, high blood pressure, over weight and obesity and extra body weight that is carried around the waste (Diabetesaustralia.com.au, 2013). All these cause the body to be unable to make enough insulin. If beta cells don’t produce enough insulin, or the body doesn’t respond to the insulin that is present, glucose builds up in the blood instead of being absorbed by cells in the body, leading to diabetes (Shuldiner, 2014).
Diabetes has being around for many centuries and it’s still a current problem in our society. There is two types of diabetes type I and type II. Type I diabetes is an autoimmune disease and the usual treatment is insulin. With type I diabetes the pancreas doesn’t produce insulin a hormone that is necessary for the body; it’s important since it acts like a taxi because it facilitates the ride of sugar (glucose). Glucose is important to the cells because they rely on glucose for energy. Insulin helps the body to balance the glucose levels: by not letting the body become hyperglycemic (high sugar levels) or
Chronic elevated glucose in blood (hyperglycemia) with disturbances metabolism of protein, fat and carbohydrate resulting from disorder in insulin secretion, insulin action, or both. (1) Expected to increase diabetic patients by 2025 to approximately 300 million people in the worldwide (2) In ancient times it was difficult to identify diabetes as the ability of patients to heal weak, the researchers think the diabetes resulting from defect in the bladder and kidneys are the cause of diabetes. (6)
Diabetes is such a broad disease that can affect all ages, genetically related people and cultures. Diabetes is sonly based on the way you treat your body including lifestyle, race, and age. It can also be passed down genetically from family generations. Depending on these factors concludes which type of diabetes a person is diagnosed with. The differences between both diseases, including their micro and macro vascular complications will help differentiate between the roles each take on everyday lifestyle of a human being diagnosed with them. Diabetes is the a major health problem and a leading
In some studies, such as Rakhshandehroo and colleagues integrated training programs, will improve significantly knowledge, attitude and performance in diabetic patients and may improve their metabolic control.[11] ( Rakhshandero et al., 2008). Sung and Kim study in south Korea showed combination of educational intervention with telephone counseling and follow-up lead to blood glucose control and improvement of self- management or self- care of diabetic patients.[12] (Song & Kim,2009) These findings confirm results of our study.
In 1962 James Neel, human geneticist proposed a hypothesis to solve a evolutionary puzzle, now known as type 2 diabetes. Need wondered why the there had been a large increase in victims when the disease was such a debilitating one. His theory, the idea that our bodies can be genetically programmed to store fat, drew a lot of criticism. When looking deeper into the past solid evidence was found supporting kneel’s hypothesis. Th mutation also showed up in apes millions of years ago, and it may pinpoint a disease that is behind many major diseases in society today. The story starts about 26 million years ago when Africa was a tropical eden.The world eventually started to coolant sea levels fell. The first series of land bridges appeared and animals
A genetic disorder called Diabetes affects nearly 25.8 million people in the U.S. alone [2]. This disease is a metabolic disorder caused by the lack of production of insulin in the body or lack of the body’s use of insulin. The body produces insulin to help our digestive system break down carbohydrates (sugars and starches) and turns them into sugars that will enter the bloodstream [1]. If there is not enough insulin produced by your body then the starches cannot be broken down and used for energy. People with this disorder have elevated glucose levels in the blood. If not treated properly, diabetes can lead to damaged nerves, amputations, debilitation, strokes and even death.
However, our understanding of what diabetes is and how it operates has changed radically within the last hundred years. When considering diabetes, it is worth noting that medical science did not discover and isolate the
Diabetes Mellitus is a chronic metabolic disorder that prevents the body to utilise glucose completely or partially. It is characterised by raised glucose concentration in the blood and alterations in carbohydrate, protein and fat metabolism. This can be due to failure in the formation of insulin or liberation or action. Since insulin is produced by the p cells of the islets of Langerhans, any receding in the number of functioning cells will decrease the amount of insulin that can be synthesised. Many diabetics can produce sufficient insulin but some stimulus to the islets tissue is needed in order that secretion can take place. During the early stages of the disease, the Insulin Like Activity (ILA) of the blood is often increased, but most of this insulin appears to be bound to protein and is not available for transport across the cell membrane and action of the cell. Globally, as of 2010, an estimated 285 million people had diabetes, with type 2 making up about 90% of the cases. In 2011 it resulted in 1.4 million deaths worldwide making it the 8th leading cause of death. This is an increase from 1 million deaths in 2000. Its rate has increased, and by 2030, this number is estimated to almost double. Diabetes mellitus occurs throughout the world, but is more common (especially type 2) in more developed countries. The greatest increase in rates is, however, expected to occur in Asia and Africa, where most people with diabetes will