Mehul Adlakha
Mr. Maiorano
CHC2D1
10 April 2015
How Dr. Frederick Banting Defined Canada
All nations attribute the positive aspects of their current status to significant events and achievements accomplished by outstanding citizens throughout history. Canada boasts of heroes and heroines who transformed its own history and that of the world at large. In 1922, one such historical figure by the name of Dr. Frederick Banting became a significant icon in the history of Canada and had managed to define a major part of both what it means to be Canadian and what Canada means to the world. Prior to Dr. Banting’s breakthrough discovery, diabetes often meant a very serious illness signifying the end of life. Dr. Banting had managed to change this
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Dr. Banting discovered that he could transfer this substance from the pancreas of one dog and inject it to another whose ability to regulate glucose levels had artificially been altered (“The Discovery of Insulin”). The results were groundbreaking and the diabetic dogs responded well to the injections, marking a major step forward in diabetes research (“The Discovery of Insulin”). Through the help of Professor John Macleod of the University of Toronto, they were able to continue their research (“The Discovery of Insulin”). Finally, in January of 1922, testing Dr. Banting’s developments in diabetes treatment on human beings had finally been completed and the results led to the ultimate development of the insulin treatment that is still used to this day (Simoni, Hill and Vaughan 31).
Dr. Banting’s research and subsequent discoveries have allowed people suffering from Type 1 diabetes throughout the world to have a chance at living healthier and happier lives. Although his work had not entirely led to a cure for the disease, it had certainly improved quality and duration of life for those suffering from it (Sherman). As an estimated 2 million people in Canada over the age of one year were known to be living with diabetes in 2006-2007 and around 10% of these patients were suffering from Type 1 diabetes, Dr. Banting’s work lives on to define his legacy and his contributions to both his country and to the world as a
Sir Frederick Banting is undoubtedly the greatest Canadian. His dedication, bravery and genius led to the discovery of insulin and a significant advance in research related to silicosis, cancer and aviation medicine. He saved millions of lives, demanding nothing in return. He did, however, receive various awards, such as the Military Cross for “distinguished and meritorious services in time of war” and the 1923 Nobel Prize in Physiology and Medicine. Not born in a particularly wealthy family, everything he accomplished was the result of hard work, commitment, and passion. He dedicated his whole life to helping people not only in Canada, but in the rest of the world as well. Banting did not just talk about making a difference like most people do. He actually got up, faced the challenge and managed to change the fate of millions.
Insulin for diabetes was discovered in 1921 at the University of Toronto by Sir Frederick G. Banting, Charles H. Best, and JJR Macleod. James B. Collip subsequently purified it, and one year later on January 11, it was put to use on a young 14 year old boy named Leonard Thompson; a patient at Toronto General Hospital. Once the substance was delivered, it was found that the extract was so pure that he suffered an allergic reaction, and further injections were cancelled. James Collip worked for the next 12 days on improving the ox-pancreas extract, and the second dose given to Thompson on January 23 was completely successful. Prior to this, a type 1 diabetic would be put on a starvation diet, or be limited to a calorie intake of around 450 calories per day, and would only live a few extra months. Leonard Thompson lived another 14 years, until 1935 when he died of pneumonia at the age of 28.
When taking the time to review the early beginnings of Canadian history through the events that would go onto lead to confederation, it is possible to realize the intent that is found in regards to the founding of the country from being a collection of colonies for the British Empire. This all in all establishes and investigation to the economic, social, political, and environmental events/ideas to go on to understand the nature of the formation of Canada, as well as the influences that would go on to the development of the national identity.
The post-war time was a period where major changes were occurring. After being involved in two international conflicts, Canada was ready to reestablish their economy. During this time, Canada had started working on ways to become stronger and reputable. It is evident that Canada had matured through the post-war era. Canada’s economic progress left a positive impact on the growth of the country as consumerism became popular, and economic ties with America became stronger. Moreover, the removal of racial and ethical barriers contributed to Canadian social affairs such as the huge wave of immigration and the baby boom. The Canadian government also had become more aware and involved in issues impacting Canadian citizens. Canada as a whole
Collips was able to purify Banting and Bests crude extract of insulin. By the 11th of January of the year 1922, a fourteen year old boy named Leonard Thompson, received the first pure extract of insulin. He was weeks away from death when he received the treatment. However, the first administration of the extract failed. A few days later, on the 23rd of January, they administered the extract again and this time it was a success! At this time, only a few patients were able to receive the insulin treatment because it could not be mass produced yet. In 1923, both Banting and Macleod were jointly awarded the Nobel Prize for medicine because of their discovery. (Turner, Novo Story of Insulin - Part 2, n.d.)
In the year 1891, on the 14th of November Frederick Banting was brought onto this world in a town 60 kilometres north of Toronto called Alliston. He was the last born of five other siblings and lived in a middle class family. Frederick Banting was an average student and had a hard time in completion of high school. He decided to study arts, however he failed. Banting always dreamt of becoming a doctor and in September 1912, the University of Toronto's Faculty of Medicine, accepted him as a student (Nobelprize.org the official web site of Nobel Prize). Banting took a strong liking to the disease known as Diabetes. His studies and research, led him to understand that insulin has control over the metabolism of sugar in the blood (Nobelprize.org the official web site of Nobel Prize). On the night of October, 31, 1920, Banting got an idea from a medical journal. He believes that if you could extract the secretion made by the pancreas, then you can further understand and advance in the treatment of diabetes ((Library and Archives Canada). Banting made the decision of moving to the University of Toronto to reveal and discuss his idea with J.J.R. Macleod. Macleod provided an opportunity for Banting and Charles Best (his assistant), to start the work on May, 17, 1921 (Library and Archives Canada). Good timing and luck were the main factors which led the Torontonian researches to announce their discovery first. This is due to the fact that many scientists in Germany and Hungary would
Insulin has been used for the treatment of diabetes since the 1920’s. Investigators have long pondered whether insulin given before the onset of diabetes could alter the course of the disease. The results demonstrate that insulin given before the onset of diabetes could
According to Kelly Lynch, a registered dietician from Cape Town, Banting is not balanced. Banting has a place in nutritional management of diabetic or insulin resistant people. Not for your every average Joe. Quote: If banting was working - I would be out of a job, and I am not.
It hasn’t been until just recently where biomechanical engineers have gotten close to doing just that. With the idea of the artificial pancreas being a dream just a couple years ago, the dream is becoming a reality right in front of us. The diabetes community is coming together to rejoice the artificial pancreas, which some companies are just months away from completing the loop of the system. With complicated algorithms and precise readings of blood glucose levels, the bionic pancreas looks as if it will have only positive effects. However, there is always a chance for this 21st century advancement to fail. Failure to proceed correct readings and appropriate dosage of insulin or glucagon could result in fatal complications and even death. Although a very slim chance of these failures to happen, there is always a possibility, but studies and research is looking very positive. The FDA has approved many products already, but most are still waiting to be furnished and made better. The artificial pancreas is an advancement that will change the medical field, both professional and patient, for centuries to
29.1 million people have diabetes in the US alone, and 371 million people in the world have diabetes. Before insulin was used to help fight diabetes, nearly everyone diagnosed with it died within a year. Then Sir Frederick Banting found that insulin helped keep people with diabetes alive for a lot longer. The upbring of this scientist, as well as his discoveries, have contributed to his popularity within the scientific community, as well as the world.
The discovery of the role of pancreas in diabetes mellitus is commonly credited to Joseph von Mering and Oskar Minkowski, who in 1889 found that dogs whose pancreas was removed developed all the diabetic signs and symptoms and died shortly afterwards. The islets of Langerhans was discovered by the anatomist Paul Langerhans in 1869. He identified the keys cells in the pancreas which produce the main hormone that controls glucose levels in the body. In 1910, Sir Edward Albert Sharpey-Schafer suggested that people with diabetes were deficient in a single chemical that was normally produced by the pancreas—he proposed calling this substance insulin (Latin insula, meaning island). The endocrine role of the pancreas in metabolism, and the actuality
How did the experts treat diabetes before they found the insulin? There are different remedial plants that are greatly extraordinary as against diabetic pros, with respect to occurrence beans and an expansive number of them have been starting now used as a part of the standard solution.
The discovery of insulin was found by physician Fredrick Banting and assistant Charles Best in 1921, Canada. The discovery was made on the pancreas
Bernardo A Houssay in 1947: discovery of the part played by the hormone of the anterior pituitary lobe in the metabolism of sugar
According to researchers at the web site diabetesinformationhub.com, diabetes has been around for a very long time but it wasn’t until around 1552 B.C. that we became aware of it. During this time, many Greek and French physicians studied it and reported on its nature, and the bodily organs that are responsible for it. In the 1870’s a French doctor uncovered a link between diabetes and the foods we ate. Therefore, changing our individual diet could be a treatment for control. Between 1900 and 1915 a diet for those with diabetes was designed to include; milk, oats, and other foods containing fiber. Another step along the path of researching this disease came when three men, Dr. Banting, Dr. Collip, and Prof. Macleod, discovered insulin and its nature and function. They were awarded the Nobel Prize for their research which took place between 1920 and 1923. In the years following many more things were discovered about this disease, for example the effects on kidneys and the skin (Diabetes information hub, history and statistics, par. 1-2). ¶