Progeria Report Essay

In the beginning of the second year, and last half of the first year the children will stop growing and gaining weight which is accompanied by the hair loss. Between the ages of two and three year the classic facial feature of the Progeria begin to show (Hennekam, 2006 pp. 2603-2624).

Progeria is one of the least known genetic disorders. There are two types of Progeria, the only difference being the age group that it affects. The Hutchinson-Gilford Progeria Syndrome is commonly called Childhood Progeria. The second type of Progeria is Werner’s Syndrome, which is the adult form of Progeria. What basically happens in this disorder is that age is accelerated seven times faster than that of a normal person. For example, for Hutchinson-Gilford Progeria Syndrome, a child could look like he is fifty when he is actually five years old. A twenty year old with Werner’s Syndrome could look similar to a sixty or seventy year old person. There is, even now, not much information known about this genetic disorder because

Hutchinson-Gilford Progeria syndrome, also known as HGPS, or Progeria, is a very rare genetic disease caused by a mutation in the cell. In 1886, Jonathan Hutchinson first reported case of a 3 ½ year old boy who had the appearance of an old man. In 1897 Hastings Gilford reported a second case with similar features. However, this mystery disease didn’t have a name until 1904, when it was named after the two men. People who have HGPS usually star showing symptoms by the age of 2, and only live to be a teen-mid-20s.

In conclusion, progeria is a deadly genetic disease characterised by premature aging. Caused by a chance occurrence in the egg or sperm, families have no warning until symptoms manifest around the age of two. Though there is treatment for the disease, there is no cure. Donating your time or money to help progeria patients is a worthy cause. Hopefully, in the future a cure will be found and progeria will not affect children around the

Experts do not believe that Progera is hereditary. They say it is due to a rare gene change, which happens purely by chance. A non-twin sibling runs the same risk of having Progera as any other child from another family. In about 1 in every 100 cases of HGPS the syndrome is passed down to the next generation within the same family. The health care professional will possibly suspect Progeria if the signs and

Some ways to detect Progeria are genetic tests of the patient’s blood and clinical exams. Furthermore, the major signs begin developing when the child is around eighteen to twenty-four months old and he will experience accelerated aging even though he was born looking normal. One major symptom is hair loss. Patients are born with hair texture and color, but around six months to two years, the hair begins to fall out. Then, from two to three years, they are usually bald, but might have some thin, light hair. Loss of eyelashes and eyebrows are also experienced. Along with hair loss, these children grow slowly resulting in a shrunken physique and minimal weight gain. For males, their approximate height and weight are 40 inches and 25 pounds; but females are about 32 inches and 20 pounds. In When Good Things Happen to Bad People, doctors have stated these kids will "grow to be very short," and "would never grow much beyond three feet."( Kusher 1-2) Moreover, there are distinctive physical traits in the face and body. "By the second year of life, there is also under development (hypoplasia) of the facial bones and the lower jaw." ("Hutchinson-Gilford Progeria") Also, "the face appears disproportionately small in comparison to the head, and bones of the front and the sides of the skull (cranium) are unusually prominent." ("Hutchinson-Gilford Progeria") Some other characteristics observed in the face are a thin

This syndrome is from a mutation of a gene on chromosome 15 and this causes problems in the production of fibrillin-1 which is a protein that is an important part of connective tissue. The name for the gene is FBN1. Basically, it is the “glue” that helps to support the tissues in the human body. A child born to a parent with this syndrome has a 50% of having it. However, in the remaining 25%, neither parent has the disease which gives them a 1 in 10,000 chance of having a child with this disorder. When a child of two unaffected parents is born with it then the genetic mutation occurs in either the egg or sperm cell at the time of conception.

It is an inherited genetic disease. It is passed down in families in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show any symptoms. Around 1 person in every 150 people are thought to be carriers. There are two types of Krabbe disease the infantile and the late on-set. The infantile form, which affects 85 to 90% of people with

muscular dystrophies. These can either be born with or you can have the gene for it or not show

Hutchinson-Gilford Progeria Syndrome is a condition in a child that has rapid growth at an early stage of childhood. The accelerating age starts in early infancy, where the child will grow slower than other children, but normal when first born. Usually the "failure to thrive" happens in the first year after being born. This condition does not stop the development of motor skills, like sitting, standing, and walking. The child will also have a normal immune system that helps with healing normally after being sick or getting scrapes/ cuts. This condition over time is life threatening to children who have been diagnosed with the progeria syndrome. Severe hardening of arteries occurs in the younger years of children, causing them to have heart attacks and strokes. Deaths have been between ages six and twenty years, the life span is usually 14.6 years after being diagnosed with the syndrome.

Hutchinson- Gilford Progeria Syndrome is reported about 1 in 8 million newborns (Parker 16). Hutchinson-Gilford Progeria Syndrome equally affects both sexes and races of children and gives them an appearance of rapid aging (Nordqvist 1). The symptoms of this disease show around eighteen to twenty-four months of

What is Progeria? Well to put it into simple terms, Progeria is a genetic mutation that causes weakened skeleton and muscles (Ho, C. Y., Jaalouk, D. E., Vartiainen, M. K., & Lammerding, J. (2013 )as well as a perceived increase in age rate which often leads to people affected with Progeria to die during their teens or even earlier. Pargein only affects 1 in every 48 million (Bhattacharya, S. (2011) children born. And in 1998 only around 80 people had it.

It was found in recents studies that KS is most commonly inherited maternally. Due to the regular levels of aneuploid sperm men produce, all men in the general public have a risk of producing an aneuploid child, therefore producing a child with KS. Knowing this, a man does not necessarily have to have KS to still produce a child with Klinefelter syndrome however it is more common for a child to inherit Klinefelter syndrome if his father also has KS.

Hutchinson-Gilford progeria syndrome is a genetic disease which consist of the rapid beginning of aging when you are an infant. This rare affection only affect 1 of 7 millions of newborns. It doesn't have a gender in particular, however, the majority of children with this condition are light skin (97% of patiences). Progeria damage different tissues like bones, muscles, skin, subcutaneous tissue and vessels. This disease do not have a cure so the kids with progeria their average life is between 8-21 years old.

scoliosis, cataracts , scars, overweight, Chrohn diseasChromosome Patterns The normal female has 46 chromosomes, of