. A 5-year-old boy is evaluated because of recurrent bacterial infections predominantly of the respiratory tract, soft tissue, and lymph nodes. Affected sites show microabscesses and granuloma formation. Staphylococcus aureus is frequently cultured from these lesions. A maternal uncle died with similar findings at 4 years of age. Laboratory studies show a deficient oxidative burst following appropriate stimulation. The most likely cause of the recurrent infections is a defect in which of the following enzymes? A) Adenine deaminase B) Catalase CMyeloperoxidase NADPH oxidase E) Superoxide dismutase

. A 5-year-old boy is evaluated because of recurrent bacterial infections predominantly of the respiratory tract, soft tissue, and lymph nodes. Affected sites show microabscesses and granuloma formation. Staphylococcus aureus is frequently cultured from these lesions. A maternal uncle died with similar findings at 4 years of age. Laboratory studies show a deficient oxidative burst following appropriate stimulation. The most likely cause of the recurrent infections is a defect in which of the following enzymes? A) Adenine deaminase B) Catalase CMyeloperoxidase NADPH oxidase E) Superoxide dismutase

Anatomy & Physiology

1st Edition

ISBN:9781938168130

Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Chapter18: The Cardiovascular System: Blood

Section: Chapter Questions

Problem 33CTQ: A patient has thalassemia, a genetic disorder characterized by abnormal synthesis of globin proteins...

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A 2-year-old African American boy is brought to his pediatrician because of acute fever, apparent bone pain, and painful swelling of his hands and feet. A physical examination reveals splenomegaly and a blood test shows the presence of hemoglobin S. After the acute symptoms subside with rest, hydration, and the use of analgesics, hydroxyurea is prescribed. This drug would be expected to reduce the risk of further acute episodes of disease via which mechanism? Increasing the synthesis of hemoglobin S Increasing the oxygen-carrying capacity of hemoglobin Reducing the oxygen-carrying capacity of hemoglobin Increasing the levels of hypoxia-inducible factor Increasing the synthesis of hemoglobin F.
27. A 35-year-old woman comes to the physician because of a 2-week history of fatigue. Six months ago, she visited family in Brazil, where she was exposed to domestic and farm animals. Physical examination shows no abnormalities except for pallor. Laboratory studies show a hemoglobin concentration of 7.2 g/dL and a hematocrit of 23%. Which of the following is the most likely causal organism? A) Enterobius vermicularis B) Necator americanus C) Schistosoma mansoni D) Taenia solium E) Trichuris trichiura
43. Which one when released from activated macrophage is responsible for fever induction during Gram (-)ve cell infection Group of answer choices interleukin 1 acetyl choline lipid A prostaglandin GABA SNARE 44. Identify the pathogen for Hansen's disease; associated with lesions confined to cooler areas of body Group of answer choices Staphylococcus aureus Helicobacter pylorii Neisseria gonorrhoeae Mycobacterium leprae Treponema palladium
A water sample is boiled for 20 minutes and plated onto nutrient agar. Growth is observed 24 hours later. Which of the following structures permit bacterial to survive the boiling process: O Peptidoglycan Biofilm Outer membrane O None of the answers apply Capsule O Endospore
42. A 25-year-old woman comes to the physician because of a 2-week history of left flank pain. She has had progressive weakness and decreased appetite during this period. Her temperature is 38°C (100.4°F). Physical examination shows left flank tenderness. Laboratory studies show a leukocyte count of 18,500/mm³. Urinalysis shows numerous RBCs and WBCS. A CT scan of the abdomen confirms an abscess of the lower pole of the left kidney. Which of the following is most likely preventing the spread of the infection to the surrounding organs? A) Fatty layer (Camper fascia) of the abdominal tela subcutanea B) Greater omentum C) Membranous layer (Scarpa fascia) of the abdominal tela subcutanea D) Pararenal fascia E) Perirenal (Gerota) fascia
You are caring for a 5-year old with lethargy and a fever of 103 F. Lungs sound are clear but the child complains of a very sore throat prior to going to bed. During transport, you observe copious secretions. Which of the following do you suspect? A) Pnemonia B) Croup C) Bacterial Tracheitis D) Epiglotis
Biopsies from the liver and intestine of an otherwise asymptomatic35-year-old male show masses of acid-fast bacilli throughout thetissue. Explain the pathology going on here and provide apreliminary diagnosis.
24. A 45-year-old man is brought to the physician because of a 3-week history of fever and facial pain. His temperature is 38°C (100.4°F), pulse is 74/min, and respirations are 14/min. Physical examination shows tenderness, edema, and erythema around the left zygomatic bone. A CT scan of the head shows that the left maxillary sinus is filled with fluid. Fiberscopic rhinoscopy is done to examine the maxillary sinus. The inserted endoscope is most likely to traverse which of the following spaces before immediately entering the maxillary sinus in this patient? A) Frontonasal duct B) Inferior meatus C) Middle meatus D) Nasolacrimal duct E) Parotid duct F) Sphenoethmoidal recess G) Superior meatus
A patient has thalassemia, a genetic disorder characterized by abnormal synthesis of globin proteins and excessive destruction of erythrocytes. This patient is jaundiced and is found to have an excessive level of bilirubin in his blood. Explain the connection.
A 60-year-old man with a long history of cigarette smoking and chronic obstructive pulmonarydisease is hospitalized with increasing shortness of breath, increasing sputum production, andlow-grade fever over a three-day period. His blood pressure is 100/ 80mmHg, pulse is 110 perminute, respiratory rate is 28 per minute, temperature is 38. 2℃. The patient is mildly cyanotic. The following arterial blood gases were obtained on room air: CaO2max =20ml/dL, CaO2 =15ml/dL, PaO2，= 50mmHg, C(a-v)O2 = 4ml/dL. Questions :1.What is the most appropriate type of hypoxia for this patient?2. What are the common causes of this type hypoxia?3. What are the characteristic alterations of blood O2 in this type hypoxia?4. What is the colour of skin and mucous membranes in this type
Explain why a person whose blood test shows an abnormallylow leukocyte count should be given an antimicrobial drugbefore a tooth extraction.
What condition do you suspect with this patient? Young man who uses a wheelchair and has trouble breathing. Furhter assessments reveals coarse rhonci in all fields with a pulse ox at 84%, Pale and greasy stool. A) Lung cancer B) Poliomyelitis C) Cystic Fibrosis D) Nyasthenia gravis