.In Drosophila, gray body color is dominant over ebony body color, while long wings are dominant over vestigial wings. Work the following crosses through the F2 generation, and determine the genotypic and phenotypic ratios for each generation. Assume that the P1 individuals are homozygous. a. Gray, long x ebony, vestigial b. Gray, long x gray, vestigial
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- In Drosophila, gray body color is dominant over ebony body color,while long wings are dominant over vestigial wings. Work thefollowing crosses through the F2 generation, and determine thegenotypic and phenotypic ratios for each generation. Assumethat the P1 individuals are homozygous: (a) gray, long * ebony,vestigial, and (b) gray, vestigial * ebony, long, and (c) gray,long * gray, vestigial.In Drosophila, a cross was made between females expressing thethree X-linked recessive traits, scute bristles (sc), sable body (s),and vermilion eyes (v), and wild-type males. All females were wildtype in the F1, while all males expressed all three mutant traits.The cross was carried to the F2 generation and 1000 offspringwere counted, with the results shown in the following table. Nodetermination of sex was made in the F2 data. Question:Calculate the coefficient of coincidence; does this represent positive or negative interference? Phenotype Offspringsc s v 314+ + + 280+ s v 150sc + + 156sc + v 46+ s + 30sc s + 10+ + v 14a. In Drosophila, crosses between F1 heterozygotes ofthe form A b / a B always yield the same ratio ofphenotypes in the F2 progeny regardless of the distance between the two genes (assuming completedominance for both autosomal genes). What is thisratio? Would this also be the case if the F1 heterozygotes were A B / a b? (Hint: Remember that inDrosophila, recombination does not take placeduring spermatogenesis.)b. If you intercrossed F1 heterozygotes of the formA b / a B in mice, the phenotypic ratio among the F2progeny would vary with the map distance betweenthe two genes. Is there a simple way to estimate themap distance based on the frequencies of the F2phenotypes, assuming rates of recombination areequal in males and females? Could you estimatemap distances in the same way if the mouse F1heterozygotes were A B / a b?
- In Drosophila, a heterozygous female for the X-linkedrecessive traits a, b, and c was crossed to a male that phenotypically expressed a, b, and c. The offspring occurred inthe following phenotypic ratios.+ b c 460a + + 450a b c 32+ + + 38a + c 11+ b + 9 No other phenotypes were observed.(a) What is the genotypic arrangement of the alleles ofthese genes on the X chromosome of the female?In the fruit fly Drosophila melanogaster, the following genes and mutations are known:Wing size: recessive allele for tiny wings t; dominantallele for normal wings T.Eye shape: recessive allele for narrow eyes n;dominant allele for normal (oval) eyes N.For each of the four following crosses, give thegenotypes of each of the parents.Male FemaleWings Eyes Wings Eyes Offspring1 tiny oval × tiny oval 78 tiny wings, oval eyes24 tiny wings, narrow eyes2 normal narrow × tiny oval 45 normal wings, oval eyes40 normal wings, narrow eyes38 tiny wings, oval eyes44 tiny wings, narrow eyes3 normal narrow × normal oval 35 normal wings, oval eyes29 normal wings, narrow eyes10 tiny wings, oval eyes11 tiny wings, narrow eyes4 normal narrow × normal oval 62 normal wings, oval eyes19 tiny wings, oval eyesGiven the following alleles that control the traits of Drosophila melanogaster:R = red eyes L = long wings B = brown bodyr = sepia eyes l = vestigial wings b = black body A testcross between a triple heterozygous parent and a recessive parent revealed the followingexpressed alleles: 55 sepia long brown 8 sepial long black187 sepia vestigial black 1 sepia vestigial brown43 red vestigial black 196 red long brown2 red long black 9 red vestigial brown Determine the order of the loci and the distance between them in centimorgan (cM). Construct agene map to show your results. Show COMPLETE solution.
- In Drosophila fruit flies, the genes for warped wings (dwp), rumpled bristles (rmp), and pallid wings (pld) are linked. A trihybrid female for all three allleles is crossed with homozygous recessive male for all three alleles and the offspring obtained showed the following phenotypes: 3 pld rmp dwp 428 pld rmp + 427 + + dwp 48 + rmp + 47 pld + dwp 23 pld + + 2 + + + 22 + rmp dwp What is the order and map distance between these three alleles?Three recessive mutations in that affect eye colour, wing shape and body colourarew, m and b. The following numbers were obtained for testcross progeny in Drosophila. Number Phenotype + m + w + b + + b w m + m b 218 236 168 178 95 101 w + + + 3 w mb 1 (i) Determine the chromosomal composition of the heterozygous female parent. Construct a genetic map of the linkage group(s) these genes occupy. Show the order and give the map distances between the genes. (ii)In Drosophila melanogaster white (w) and miniature (m) wings are controlled by X-linked recessive genes with a recombination fruequency between them of approximately 38%. Show the sexes, phenotypes and proportions of offspring expected from the following mating:a. ++/wm female X wm maleb. +m/w+ female X w+ malec. w+/+m female X ++ maleIf we assume that white eyes and miniature wings are not x-linked but are linkedto the autosomal genes, what phenotypic frequencies would you expect from this cross: ++/wm female X ++/wm male?
- . The normal eye color of Drosophila is red, but strains inwhich all flies have brown eyes are available. Similarly,wings are normally long, but there are strains with shortwings. A female from a pure line with brown eyes andshort wings is crossed with a male from a normal pureline. The F1 consists of normal females and short-wingedmales. An F2 is then produced by intercrossing the F1.Both sexes of F2 flies show phenotypes as follows:38 red eyes, long wings38 red eyes, short wings18 brown eyes, long wings18 brown eyes, short wingsDeduce the inheritance of these phenotypes; useclearly defined genetic symbols of your own invention.State the genotypes of all three generations and thegenotypic proportions of the F1 and F2.Unpacking Problem 31Before attempting a solution to this problem, try answering thefollowing questions:1. What does the word normal mean in this problem?2. The words line and strain are used in this problem.What do they mean, and are they interchangeable?3. Draw a simple…A Drosophila embryo dies during early embryogenesis due to arecessive maternal effect allele called bicoid−. The wild-type alleleis designated bicoid+. What are the genotypes and phenotypes ofthe embryo’s mother and maternal grandparents?. In Drosophila, three loci, Bar eyes (B, dominant), Scalloped wings (sd, recessive), and tanbody (t, recessive) are all located on the X chromosome. Bar eyes is located at position57, scalloped wings at position 51.5, and tan body at position 27.5. A female whosemother was homozygous dominant at all three loci and whose father was hemizygousrecessive at all three loci produces 1000 egg cells. How many TsdB cells would youexpect if chromosomal interference = 0? ____6-7_______ why is that the answer?