1.2 A 50 year old male, who is a chronic alcoholic, presented with dyspnea, and high output cardiac failure. Investigation revealed cardiomegaly, and reduced erythrocyte transketolase activity. Which vitamin is deficient in this patient.Explain
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- Which LDH isoenzyme is elevated in myocardial infarction? Explain why. What LDH isoenzyme can be use as a liver function test? Explain why.A 67-year-old woman complains of gradually increasing fatigue. On physical examination, she is found to be anemic and has a peripheral neuropathy characterized by loss of position and vibratory sense. Laboratory studies docu- ment a macrocytic anemia and decreased WBC and platelets counts. What pathological mechanism accounts for these findings? Myelodysplastic sideroblastic anemia Chronic blood loss Autoantibodies against parietal cells or intrinsic factor Diabetes mellitus A diet deficient in folateProvide the expected result of clotting time if the patient is afflicted with the following condition. P if Prolonged and N if Normal. 1.1 Vascular Disorder 1.2 Fibrinogen Deficiency 1.3 Prothrombin Deficiency 1.4 Factor VII Deficiency 1.5 Classic Hemophilia
- A 48-year-old woman of Mediterranean de- scent presents because of fatigue, arthralgias, discomfort in her right upper abdominal quad- rant, and polyuria. Laboratory tests are remark- able for elevated glucose level, elevated biliru- bin, low hemoglobin, elevated reticulocytes, and increased transferrin saturation. Cardiac testing shows moderate restrictive cardiomyop- athy. She frequently has required blood trans- fusions throughout her life. Which hereditary disorder does this patient most likely have? (A) Absence of the hemoglobin a-chain (B) Absence of the hemoglobin b-chain (C) Mutation resulting in increased absorption of dietary iron (D) Mutations in the gene encoding ankyrin (E) Mutations resulting in copper accumula- tionDiscuss the risk factors for, the pathogenesis of, and the consequences of, coronaryartery atherosclerosis and comment on the possible causes and the subsequentpathologic findings that could occur with a total serum cholesterol of 268 mg/dl.TU 27. 50 years male patient complaining of fatigue for the past one year. His blood workup shows presence of anemia TLC more than 1 lac/ microl and peripheral smear showing neutrophil; basophils; myeloblasts; myelocytes and metamyelocytes. Which of the following is the most specific further investigation?
- The hyperviscosity shndrome can cause cardiac ischemia by impairing micro circulation and this syndrome is associated with erythrocytosis, leukocytes is, or hypercholesterolemi. For each condition provide a definition, indicate two causes for each condition and give the normal values.A 67 years old female patient. She presented to her GP last week, complaining of a very strong headache, followed by dizziness. The symptoms had resolved by the time she could see the GP, who was concerned enough to request a CT of her head and neck. Diabetes mellitus Type 2: Management: metformin 1000mg, daily enalapril 10 mg daily rosuvastatin 10mg, daily Atrial fibrillation (AF) Management: apixaban 2.5 mg, BD sotalol 40 mg, BD Cigarette smoking: 20 - 30 cigarettes/day, quit 5 years ago. She underwent a CT scan of the head and neck, but the results were normal. the patient was assessed as requiring changes to her hypertension & AF management and the following changes made: enalapril ceased the following medications commenced or changed; irbesartan/ hydrochlorothiazide 300/25, daily amlodipine 5mg, daily apixaban 5mg, BD This morning patient woke up at 0600 hours with a 5/10 headache. At 0700 hours she began to feel weak in her limbs, and her headache increased to…Name all the cells that are found in the bone marrow under each type of hemopoiesis ERYTHROPOIESIS GRANULOPOIESIS AGRANULOPOIESIS
- Interpret the following laboratory result in relation to the diagnosis of Myocardial Infarction (MI): CK-MB - POSITIVE Troponin I – NEGATIVE FBS – 250 mg/dL HbA1c – 12.5% NT-proBNP – 5,380 pg/mLa brief description of the following disorders and the type of formed element ved. Disorders Description Forme Specific genetic mutations lack of specific clotting factors required in the clotting cascade continued internal bleeding Clotuting & IX are nophilia liver cll astic anemia nolytis anemiaMacropreparation №o 2 "Tiger heart" (myocardial lipidosis) Description of macropreparation: Diagnosis: 1 2 located near and Micropreparation №o 2 <SEE MORE QUESTIONS