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- 18. Esmolol 1.2 g in 500 mL D5W has been ordered at a rate of 100 mcg/kg/min for a client weighting 103.2 kg. Determine the following: a) dosage in mcg/min: b) rate in mL/hr c) Is the dosage administered to the client safe?6. A solution made up of 500 mL of 50% dextrose, 500 mL of 8.5% Aminosyn, and 300mL of sterile water for injection is ordered. a) What is the total weight (in grams) of the dextrose? b) What is the total weight (in grams) of Aminosyn? c) 20 mEq of KCI are needed in the infusion above. How many mL of KCI should be added? Stock strength available: KCl 2 mEq/mL d) 22 mEq of NaCl are also needed in the infusion. What volume of NaCl should be added? Stock strength available: NaCl 4.4 mEq/mL e) What is the total volume of solution with the original fluids and the addition of KCI and NaCl?22. VIRAMUNE Oral Suspension contains 1% w/v of nevirapine. Calculate the milli- grams of nevirapine present in a 240 mL bottle of the suspension. 22. 2400 mg nevirapine
- 4. (a) If a 10-mL vial of insulin contains 100 units of insulin per milliliter, and a pa- tient is to administer 20 units daily, how many days will the product last the pa- ра- tient? (b) If the patient returned to the pharmacy in exactly 7 weeks for another vial of insulin, was the patient compliant as indicated by the percent compliance rate? 5. A prescription is to be taken as follows: 1 tablet q.i.d. the first day; 1 tablet t.i.d. the second day; 1 tablet b.id. X 5 d; and 1 tablet q.d. thereafter. How many tablets should be dispensed to equal a 30-day supply?11. NEUPOGEN (filgrastim) prefilled sy- ringes contain 480 mcg of active constitu- ent in each 0.8 mL. The equivalent con- centration is: (a) 0.6% (b) 0.384 mg/mL (c) 0.06% (d) 0.6 g/mL 11. (c) 0.06%What is the difference between Cockroft gault formula and Ckd-epi creatinine equation? Does both measures creatine clearance? What is more accurate to use? Based on the table below, what would be the recommended dosage of "Levofloxacin 500 mg IV every 24 hours" if the 72-year-old patient weight is 78 kg and has a serum creatinine: 3.2 mg/dL?
- An order reads: Daptomycin in NS IV Administer 8 mg/kg over 30 min q24 hrs x 10 days How many milliliters of a vial containing 500 mg of daptomycin in 10 mL should be added to a 100 mL bag of NS to follow the order above to treat a 245-lb patient?40. A metronidazole vaginal gel contains 0.75% of drug in 70-g tubes. An applica- tor will hold 5 g of gel for each adminis- tration. How much drug will be contained in each application? (a) 0.0375 mg metronidazole (b) 3.75 mg metronidazole (c) 37.5 mg metronidazole (d) 375 mg metronidazole 40. (c) 37.5 mg metronidazole27. Oxycodone hydrochloride oral concen- trate solution (OXYFAST) contains 20 mg/ 1 mL. If a dose of 0.75 mL is added to 30 mL of juice prior to administration, calcu- late (a) the milligrams of oxycodone hy- drochloride administered, and (b) the per- centage concentration (w/v) of oxycodone hydrochloride in the drink. 27. (a) 15 mg oxycodone hydrochloride (b) 0.049% w/v oxycodone hydrochlo- ride
- a) The total amount excreted into urine as unchanged drug after an oral tablet (A) of 50 mg was 36.4 mg. After an oral capsule dose (B) of 25 mg the Uo was 20.3 mg. Calculate the relative bioavailability of the tablet A with respect to capsule B. If the absolute bioavailability of the oral capsule is determined to be 0.86 calculate the absolute bioavailability of the tablet dosage form. You are required to list the given data, formula and steps for calculationsA 40kg child has been prescribed an initial loading dose of warfarin 0.2mg/kg PO. Warfarin is available in 1mg, 2mg, 2.5mg, 3mg, 4mg, 5mg, 6mg, 7.5mg and 10mg scored tablets. a) How many mg will the child receive, and which tablet strength would you use? b) On day 2, the INR comes back at 2.5 with a dosing protocol to reduce dose to 50% of the initial loading dose. How many mg would you administer, and which tablet strength would you use?The order in the MAR is for Atropine 15 mg IV q6h hours PRN. How many mL will you give if the dosage strength is 75mg/7.5mL?