14. Which of the following cells probably do produce pyrogens? a. Red blood cells that express MHC I b. endothelial cells that line blood vessel cell walls C. T helper cells d. B cells e. Other leukocytes such as macrophages 15. Your patient obtained a Vibrio cholerae infection from drinking contaminated water. The organism releases vibriobactin which is a siderophore which is a bacterial protein used to capture iron. To counter the action of this bacterial protein, your patient produces a. interferon b. transferrin c. pyogens d. perforin e. histamine 16. Which of the following would not be an effective antiviral against bacteriophages? a. An agent that blocks lysozyme b. An agent that blocks nucleic acid synthesis c. An agent that blocks intracellular uncoating d. An agent that blocks restriction enzymes e. An agent that promotes extracellular uncoating 17. Which of the following statements is not true a. interferon is cytolytic b. ribosomes are the target for antimicrobials that target protein synthesis c. red blood cells does not contain MHC I

14. Which of the following cells probably do produce pyrogens? a. Red blood cells that express MHC I b. endothelial cells that line blood vessel cell walls C. T helper cells d. B cells e. Other leukocytes such as macrophages 15. Your patient obtained a Vibrio cholerae infection from drinking contaminated water. The organism releases vibriobactin which is a siderophore which is a bacterial protein used to capture iron. To counter the action of this bacterial protein, your patient produces a. interferon b. transferrin c. pyogens d. perforin e. histamine 16. Which of the following would not be an effective antiviral against bacteriophages? a. An agent that blocks lysozyme b. An agent that blocks nucleic acid synthesis c. An agent that blocks intracellular uncoating d. An agent that blocks restriction enzymes e. An agent that promotes extracellular uncoating 17. Which of the following statements is not true a. interferon is cytolytic b. ribosomes are the target for antimicrobials that target protein synthesis c. red blood cells does not contain MHC I

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter17: The Immune System And Disease

Section: Chapter Questions

Problem 15RQ: Autoantibodies are probably involved in ________. a. reactions to poison ivy b. pollen allergies c....

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1. Which of the following sentences is CORRECT? A .P53 is an example of tumour activator gene B. leukotrienes are derived from arachidonic acid by cyclooxygenase C. effective bacteriocidal enzymes are contained in lysosome of the lymphocytes D. Gram stain is the most commonly used tissue stain for routine histological examination E .proteoglycans are located in ground substance of the ECM in connective tissues and basement membrane
22. Which of the following is NOT a characteristic of cell- mediated immunity? a. The cells originate in bone marrow b. Cells are processed in the thymus gland c. The activation of cell-mediated immunity can be suppressed d. They are antigen presenting cells e. All of the above are characteristics of cell-mediated immunity 23. All of the following could be possibly target sites for antimicrobials to limit the possibility of side effects except a. peptidoglycan b. parasitic glycolytic enzymes c. ergosterol C. d. RNA polymerase DNA gyrase e. 24. Lysogeny can result in all of the following EXCEPT a. persistent infections b. a bacteria expressing new genes c. transduction of genes C. d. the turning off of the host cell's transcriptional and translational machinery e. the definite destruction of an infected cell 25. Due to your patient's opsonization of a bacterial cell with C₂B, which of following did NOT occur a. interference of the patient's secondary viral infection b. bacterial cell…
55. Identify a MISMATCHED pair from the following, Group of answer choices lethal factor :::: protease activity; inhibits chemokine production. edema factor :::: unregulated cAMP synthesis protective antigen :::: binds and assembles at target cell membrane protective antigen :::: acts as a biosensor ; detects higher temperature of the digestive system to become active protective factor :::: aids in bringing other toxins components inside cell via endocytosis 56. Which of the following holds TRUE for blood agar medium? Group of answer choices gamma hemolysis is when there is no effect on red blood cells. alpha hemolysis is due to complete breakdown of red blood cells beta hemolysis is the incomplete breakdown of red blood cells. we always use human red blood cells in blood agar blood agar medium belongs to selective media
Your patient who is recovering from a first time wound infection caused by Staphylococcus aureus. Which of the following would you not find in a sample of your patient’s wound exudate?a. IgM after 3 days of the infection b. neutrophils c. histamine d. macrophages e. Pyrogens
18. Antiviral proteins synthesized in response to the binding of interferon may target a. intracellular uncoating b. nucleic acid synthesis c. viral assembly C. d. viral ribosomes e. all the above except d 19. When a macrophage encounters S. aureus, which of the following will most likely not occur? a. The macrophage will indirectly induce the synthesis of an antibody b. The macrophage will activate T cells C. The macrophage will produce cytokines d. The macrophage will exhibit its phagocytic and antigen presenting traits e. a & b 20. Plasma cells are actually activated by a. an antigen b. a T cell c. a B cell d. a memory cell PRRS e. 21. Development of resistance to a particular antimicrobial is limited if the drug a. binds to several sites on the target molecule b. targets several different molecules c. affects only one molecule d. affects the plasma membrane e. a and b
7. Cells produce mRNA by transcription of their DNA genomes. In contrast, single-stranded RNA genome viruses have three different strategies with respect to viral mRNA production. Briefly describe the production of mRNA for each of the following viruses. a. Poliovirus b. Vesicular stomatitis virus c. Rous sarcoma virus 8. Infection of a human with influenza virus can trigger both host defense systems: the interferon response and the immune response. In the table below, indicate with a “Yes" or a “No" regarding which of the events is characteristic of which defense system (either, both, or neither). The Interferon Immune Event The Response Response Both host and viral mRNA are degraded in the cell after infection. A fragment of viral protein in complex with major histocompatibility complex type I is displayed on the surface of the infected cell. The virally infected cell dies. Capped mRNA is no longer translated in the infected cell.
MATCH THE CORRECT WORDS TO THE DEFINITION A. spontaneous hydrolysis B. Random Generation C. C3 convertase D. membrane-attack complex E. Classical and lectin F. Antigen-antibody immune complex G. Microbial carbohydrates H. Decay-accelerating Factor (DAF) I. Short half-life J. Factor I
48. Sjogren's syndrome is an autoimmune disorder where the tear duct glands are no longer producing tears so the patient experiences dry eye. One of the treatments for Sjogren's syndrome is cyclosporine, an immunosuppressive information, cyclosporine agent. Based on this a. activates histamine production b. directly deactivates neutrophils c. activates leukocidin activity d. indirectly deactivates Tc cells e. activate macrophage activity ||
FceRI binds A. IgA B. IgG C. IgE D. Innocuous substances Aspirin reduces inflammation by acting on: A. Histamine B. Chymotryptase C. Leukotrienes D. Prostaglandins
5. A diagram of an antibody IgG molecule is given below. Indicate the locations of the following items on the diagram by putting the letter next to those parts of the molecule. If a part occurs more than once, mark all copies of the part. If you want you can draw the structure, mark it, take a picture, and insert the photo. (a) (b) (d) (e) the heavy chains the light chains the antigen binding site(s) the hinge region the Fc region
Gram negative cell walls contain lipopolysaccharide (LPS) as a unique component. All of the following apply to LPS EXCEPT O LPS is composed of mycolic acids that protect the cell from phagocytosis LPS is a PAMP that can be recognized by toll-like receptors (TLRS) as a foreign molecule fo rphagocytosis O LPS can be a target for specific IgG for ADCC-opsonization LPS can be recognized by B cells in the aosence of MHC molecules All of the answers apply, no exception O LPS is found in the outer membrane of Gram negative cells
14. Predominant cell types involved in the humoral immune response are: A. eosinophils. B. macrophages. C. neutrophils. D. B cells 15. T helper cells recognize which of the following? A. Exogenous peptide bound to class II MHC B. Native extracellular viral proteins C. Endogenous peptides bound to class I MHC D. Microbe-specific structures 16. How are cytotoxic T cells and natural killer cells similar? A. Both require antibędy to be bound to the target cell. B. Both induce apoptesis in the target cell C. Both recognize peptide plus MHC class I. D. Both kill target cells lacking MHC class I. 17. Perforin and granzymes are used by which cells to kill target cells? A. CD8 T cells and CD4 T cells B. CD4 T cells and natural killer cells C. Natural killer cells and B cells D. CD8 T cells and natural killer cells