156. Numerous cross-sectional studies in different populations have shown a significant relationship between the use of tanning beds and the development of melanoma. The odds ratios of these studies range from 3.2 to 7.1. In these studies, the number of hours of tanning bed use was highly correlated with an increase in the size and number of dysplastic nevi. Which of the following is the greatest limitation in establishing causality from these studies? A) Biologic plausibility B) Consistency of the findings C) Dose response D) Strength of association E) Temporal sequence of events

156. Numerous cross-sectional studies in different populations have shown a significant relationship between the use of tanning beds and the development of melanoma. The odds ratios of these studies range from 3.2 to 7.1. In these studies, the number of hours of tanning bed use was highly correlated with an increase in the size and number of dysplastic nevi. Which of the following is the greatest limitation in establishing causality from these studies? A) Biologic plausibility B) Consistency of the findings C) Dose response D) Strength of association E) Temporal sequence of events