6. The boiling points of various organic compounds are given below. Explain the reasons for the different boiling points. How do the functional groups of each compound effect their boiling points? Compound Propanoic acid 1-propanol 1-propanamine Propanal Propane Boiling Point 141°C 97°C 51°C 48°C -42°C

Organic Chemistry
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ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
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Chapter10: Alcohols
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Please answer 6,7,8

6. The boiling points of various organic compounds are given below. Explain the reasons for the different boiling
points. How do the functional groups of each compound effect their boiling points?
Compound
Propanoic acid
1-propanol
Boiling Point
141°C
97°C
1-propanamine 51°C
48°C
-42°C
Propanal
Propane
7. The compound shown is a common artificial sweetener. Circle and identify the functional groups in the
molecule. Which functional groups can undergo hydrolysis? Draw structures to show the complete hydrolysis
(either acidic or basic) of the compound. (Hint: hydrolysis may occur in more than one location.)
HO
NH₂
CH₁ CH₂ - CH₂
Valproic Acid
8. a) Valproic acid is an anti-seizure medication often administered in a sodium salt form. Draw out the reaction
showing how the sodium salt of valproic acid is formed. Why is the salt form used?
CH3CH₂CH₂
NH
CH - C
HH
phenylpropanolamine
b) Phenylpropanolamine (PPA) is a decongestant and appetite suppressant medication that is no longer available
in the US and Canada because of its association with increased stroke risk. It is administered in a hydrochloride
salt form. Draw out the reaction showing how the hydrochloride salt of phenylpropanolamine is formed. Why is
the salt form used?
CNH,
OH CH3
CH3
OH
Transcribed Image Text:6. The boiling points of various organic compounds are given below. Explain the reasons for the different boiling points. How do the functional groups of each compound effect their boiling points? Compound Propanoic acid 1-propanol Boiling Point 141°C 97°C 1-propanamine 51°C 48°C -42°C Propanal Propane 7. The compound shown is a common artificial sweetener. Circle and identify the functional groups in the molecule. Which functional groups can undergo hydrolysis? Draw structures to show the complete hydrolysis (either acidic or basic) of the compound. (Hint: hydrolysis may occur in more than one location.) HO NH₂ CH₁ CH₂ - CH₂ Valproic Acid 8. a) Valproic acid is an anti-seizure medication often administered in a sodium salt form. Draw out the reaction showing how the sodium salt of valproic acid is formed. Why is the salt form used? CH3CH₂CH₂ NH CH - C HH phenylpropanolamine b) Phenylpropanolamine (PPA) is a decongestant and appetite suppressant medication that is no longer available in the US and Canada because of its association with increased stroke risk. It is administered in a hydrochloride salt form. Draw out the reaction showing how the hydrochloride salt of phenylpropanolamine is formed. Why is the salt form used? CNH, OH CH3 CH3 OH
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