7. Many pharmaceuticals contain aromatic rings or large hydrocarbon areas (nonpolar). Quite often, pharmaceuticals are synthesized in an ionic form to increase their solubility in aqueous solution. Ionic charges on organic molecules dramatically increase the compound's solubility. Predict whether the following pharmaceuticals are likely to be soluble in water based on their polarity and the distribution of polarity throughout the compound.

Chemistry & Chemical Reactivity
9th Edition
ISBN:9781133949640
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Chapter13: Solutions And Their Behavior
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7. Many pharmaceuticals contain aromatic rings or large hydrocarbon areas
(nonpolar). Quite often, pharmaceuticals are synthesized in an ionic form to
increase their solubility in aqueous solution. Ionic charges on organic molecules
dramatically increase the compound's solubility. Predict whether the following
pharmaceuticals are likely to be soluble in water based on their polarity and the
distribution of polarity throughout the compound.
Pentolinium-an antihypertensive
Methamphetamine-mainly
recreational usage yet sometimes
prescribed for ADHD
RemeronTM-an antidepressant
8. Devise a rule to predict the solubility of an organic compound in water.
Transcribed Image Text:7. Many pharmaceuticals contain aromatic rings or large hydrocarbon areas (nonpolar). Quite often, pharmaceuticals are synthesized in an ionic form to increase their solubility in aqueous solution. Ionic charges on organic molecules dramatically increase the compound's solubility. Predict whether the following pharmaceuticals are likely to be soluble in water based on their polarity and the distribution of polarity throughout the compound. Pentolinium-an antihypertensive Methamphetamine-mainly recreational usage yet sometimes prescribed for ADHD RemeronTM-an antidepressant 8. Devise a rule to predict the solubility of an organic compound in water.
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