A 50-year-old man was rushed in the Emergency Room with a history ofexpelling black covered stools for two day, and recurrent nosebleeds. His completepatient history reveals both a recent as well as historyof ethanol abuse. Hiscoagulations studies reveal:PLATELET COUNT:PT:APTT:THROMBIN TIME:FIBRINOGEN:FDP:60X10^9/L20 sec52 sec11 sec201mg%>40mg/ml1. What is the most probable diagnosis?2.What could be the cause of the Hemostasis Test results? Explain the answer.3. Given the test results, what symptoms would be expected to manifest in the patient?4. If a mixing study would be performed, what would be the expected result?5. Are there any other test that may be done to confirm if other hemostatic disorder are present?

Coagulation Disorder: A coagulation disorder is a medical condition in which the body's normal blood…

Answered: A 50-year-old man was rushed in the…

Biomedical Instrumentation Systems

1st Edition

ISBN:9781133478294

Author:Chatterjee

Publisher:Chatterjee

Chapter9: Instrumentation In Blood Circulation

Section: Chapter Questions

Problem 1CS

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A 10-year-old boy with known HbSS disease presented to the Paediatric Emergency Department with a oneweek history of fever and severe pain in his right leg, severity 9/10 for the last two days. On examination:Pulse – 100 beats/min, BP – 110/70 mmHg, Capillary refill < 2sec and Respiratory rate – 20 breaths/ min. He has point tenderness anteriorly on proximal tibia. There is no joint swelling.X-ray of the affected limb shows marked periosteal elevation.His complete blood count is: Hb – 6.5 g/dL WBC 30 x 10 /L Plt – 120 x 10 /L with a reticulocyte count of 1%.Of the following the MOST appropriate management in this patient would bea. Ibuprofen, Cefotaxime and top-up transfusionb. Morphine, Ampicillin and hydration therapyc. Morphine, Cefotaxime and hydration therapyd. Morphine, Cefotaxime and top-up transfusion
A 24-year-old male presented with confusion, shortness of breath, and painful calves. It was reported by a friend that he had been lying on the floor for several hours. He was a known intravenous heroin and alcohol abuser. On examination he appeared dehydrated and cold (tem- perature 35°C); his pulse was 75/minute and blood pres- sure 110/70 mmHg. Intravenous injection sites were apparent. His urine was dark coloured. His chest was clear. Arterial blood gases were done in the casualty department and a blood sample was sent to the pathology department and gave the following results (reference ranges are given in brackets): Arterial blood pH PCO₂ PO₂ HCO3- Serum Sodium Potassium Creatinine Calcium Albumin Phosphate Creatine kinase C-reactive protein 7.276 4.82 KPa 12.7 kPa 18.0 mmol/L 138 mmol/L 7.6 mmol/L 236 μmol/L 1.66 mmol/L 32 g/L 2.43 mmol/L >140,000 U/L 73 mg/L (7.35-7.45) (4.7-6.0) (12.0-14.6) (24-29) (135-145) (3.8-5.0) (71-133) (2.10-2.55) (35-50) (0.87-1.45) (55-170) (<10) The…
A 62-year-old man is initially seen in the Emergency Room complaining of difficulty with speech and swallowing due to an enlarged tongue. Physical examination also reveals a large, sublingual hematoma. In addition, multiple ecchymoses of his skin are noted. He has no history of trauma nor has there been any pervious episodes of bleeding. Coagulation studies show: Platelet Count: 180,000/cumm PT: 12 sec APPT: 72 sec TCT or thrombin time: 10 sec Fibrinogen: 225% Additional laboratory studies reveal: (Mixing Studies) Normal plasma: 20% 50% 80% Patient plasma 80% 50% 20% Repeat APPT: 72 sec 70 sec 68 sec Questions: What additional Laboratory test to confirm the diagnosis? Give the relevance of the laboratory tests ordered to the case. Why it is necessary?
A 62-year-old man is initially seen in the Emergency Room complaining of difficulty with speech and swallowing due to an enlarged tongue. Physical examination also reveals a large, sublingual hematoma. In addition, multiple ecchymoses of his skin are noted. He has no history of trauma nor has there been any pervious episodes of bleeding. Coagulation studies show: Platelet Count: 180,000/cumm PT: 12 sec APPT: 72 sec TCT or thrombin time: 10 sec Fibrinogen: 225% Additional laboratory studies reveal: (Mixing Studies) Normal plasma: 20% 50% 80% Patient plasma 80% 50% 20% Repeat APPT: 72 sec 70 sec 68 sec Question: What additional Laboratory test to confirm the diagnosis? Give the relevance of the laboratory tests ordered to the case. Why it is necessary?
A 62-year-old man is initially seen in the Emergency Room complaining of difficulty with speech and swallowing due to an enlarged tongue. Physical examination also reveals a large, sublingual hematoma. In addition, multiple ecchymoses of his skin are noted. He has no history of trauma nor has there been any pervious episodes of bleeding. Coagulation studies show: Platelet Count: 180,000/cumm PT: 12 sec APPT: 72 sec TCT or thrombin time: 10 sec Fibrinogen: 225% Additional laboratory studies reveal: (Mixing Studies) Normal plasma: 20% 50% 80% Patient plasma 80% 50% 20% Repeat APPT: 72 sec 70 sec 68 sec Question: What additional Laboratory test to confirm the diagnosis? Give the relevance of the laboratory tests ordered to the case. Why it is necessary?The additional test is von willebrand test because it's specific for clotting factor 8. Why is it necessary?
Hemodynamic Monitoring Case Study: A 67-y.o woman is admitted to the ICU with a dx. of hypotension of unknown origin. She is presently unresponsive but is breathing spontaneously on her own. Lungs are clear, urinary output is 15ml in 8 hours, and her skin is cool. A PA catheter is inserted to obtain more information and guide therapy. The following information is revealed: BP 86/54mmHg PAWP 4mmHgP 118/min CVP 2mm/HgRR 30 breaths/min SVR 1393 dynesC.O. 3.5 L/min PVR 195 dynesC.I. 1.9 L/min SvO2 50%PA 24/10mmHg Which Values tell us about this patient's filling pressures/fluid status? Are these values adequate? Which Values tell us about this patient's contractility? Are these values adequate? Which values tell us about this patient’s vascular resistance? What is causing this patient's hypotension? Which initial therapy is appropriate?
What are the SIDE EFFECT/ADVERSE EFFECT of the erythromycin drug? please take note of the low blood pressure of the patient. based on the ff situation: DRUG: Erythromycin Age: 7 Sex: F Educational status: N/A Occupation: Pupil Weight and BMI: 23 KGS/NORMAL Blood pressure: 80/40 Heart rate: 90 Respiratory rate: 20 Temperature: 36.2 Diagnosis: Conjunctivitis, Left eye Chief complaint: Red eyes, discharges in eyes Prescription: Erythromycin 2% ointment in lower conjunctiva

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