A chemist failed to generate the diol using the reaction shown here. OH 1. BrMg Но. Но. H 2. H;O* quench Not formed Part A Suggest a reason why this reaction did not work as written. How could the reaction conditions be modified to allow formation of the diol? Match the items in the left column to the appropriate blanks in the sentences on the right. Reset Help electrophile The acidic proton on the primary carbon is a competing and will react with and nucleophile destroy the Grignard reagent. the tertiary carbon To perform the synthesis, one should put the protecting group on first, then make the the secondary carbon desired reaction, and, finally, remove the protecting group from the OH group the primary carbon the carbonyl group

A chemist failed to generate the diol using the reaction shown here. OH 1. BrMg Но. Но. H 2. H;O* quench Not formed Part A Suggest a reason why this reaction did not work as written. How could the reaction conditions be modified to allow formation of the diol? Match the items in the left column to the appropriate blanks in the sentences on the right. Reset Help electrophile The acidic proton on the primary carbon is a competing and will react with and nucleophile destroy the Grignard reagent. the tertiary carbon To perform the synthesis, one should put the protecting group on first, then make the the secondary carbon desired reaction, and, finally, remove the protecting group from the OH group the primary carbon the carbonyl group

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter4: Acids And Bases

Section: Chapter Questions

Problem 4.10P: Complete a net ionic equation for each proton-transfer reaction using curved arrows to show the flow...

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