2. A limitation of the Friedel-Crafts alkylation reaction is that the presence ofmoderately/strongly deactivating groups results in poor yields. Consider aniline,which is not very reactive towards Friedel-Crafts alkylation.NH2a. Is the -NH2 group deactivating relative to H?Page 1 of 3b. Why does this substituted benzene derivative not give good yields ofalkylated product when subjected to Friedel Crafts alkylation using an alkylhalide and AICI, Lewis acid?

Friedel-Crafts alkylation is a kind of electrophilic substitution reaction and in this kind of…

A limitation of the Friedel-Crafts alkylation reaction is that the presence of moderately/strongly deactivating groups results in poor yields. Consider aniline, which is not very reactive towards Friedel-Crafts alkylation. NH2 -NH2 group deactivating relative to H? a. Page I of 3 b. Why does this substituted benzene derivative not give good yields of alkylated product when subjected to Friedel Crafts alkylation using an alkyl halide and AICI3 Lewis acid?

A limitation of the Friedel-Crafts alkylation reaction is that the presence of moderately/strongly deactivating groups results in poor yields. Consider aniline, which is not very reactive towards Friedel-Crafts alkylation. NH2 -NH2 group deactivating relative to H? a. Page I of 3 b. Why does this substituted benzene derivative not give good yields of alkylated product when subjected to Friedel Crafts alkylation using an alkyl halide and AICI3 Lewis acid?

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter19: Eas: Electrophilic Aromatic Substitution

Section: Chapter Questions

Problem 17E

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