A mixture of the three compounds shown below is separated, using a 2.1x150 mm C8 column in 10-30% acetonitrile/water, and at a flow rate of 1mL/min. Three peaks are seen in the resulting chromatogram at 6.12, 6.25 and 6.98 minutes. Void time = 1.2 minutes. но. NH -Ph 4-methylpentanoic acid (R)-4-benzyloxazolidin-2-one N. Ph (R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

EBK A SMALL SCALE APPROACH TO ORGANIC L
4th Edition
ISBN:9781305446021
Author:Lampman
Publisher:Lampman
Chapter91: Gas Chromatography
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What would the elution order of these compounds be? Why?

A mixture of the three compounds shown below is separated,
using a 2.1x150 mm C8 column in 10-30% acetonitrile/water,
and at a flow rate of 1mL/min. Three peaks are seen in the
resulting chromatogram at 6.12, 6.25 and 6.98 minutes. Void
time = 1.2 minutes.
HO.
`NH
-Ph
4-methylpentanoic acid
(R)-4-benzyloxazolidin-2-one
Ph
(R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one
Transcribed Image Text:A mixture of the three compounds shown below is separated, using a 2.1x150 mm C8 column in 10-30% acetonitrile/water, and at a flow rate of 1mL/min. Three peaks are seen in the resulting chromatogram at 6.12, 6.25 and 6.98 minutes. Void time = 1.2 minutes. HO. `NH -Ph 4-methylpentanoic acid (R)-4-benzyloxazolidin-2-one Ph (R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one
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