A signaling pathway is show below answer the following questions related to this pathway. What is the receptor type? Is the pathway direct or indirect? Are there any second messengers, if so what are they? A. B. C.
Q: Explain the Crosstalk between 2nd messenger systems and the purpose of each step of the pathway.
A: There is crosstalk between different second messenger systems in the cell. This crosstalk allows for…
Q: This question pertains to membrane transport & cell signaling. Give an example of animals and…
A: Cell signaling is used as a mechanism for communication between cells. The signaling cell releases…
Q: a. Molecule X is a soluble protein that is secreted in response to extracellular signal Y. Which…
A: Sorting is an important process in the transportation of the signalling molecules from one cell to…
Q: The figure below shows a signaling pathway activated by the binding of adrenaline to the…
A: The hormones are chemical messengers that activates specific cell signalling pathway in the target…
Q: Which of these is NOT a response that occurs when an intercellular chemical signal binds to a…
A: There are three kinds of signaling cascade through which cell receives a signal to the plasma…
Q: A. What is the original ligand in the image? B. What is the second messenger in this pathway? C.…
A: Cellular signaling is a process of communication or passing form one cell to another by signaling…
Q: important neurotransmitter agonists.
A: The signal transduction between the interactions of the ligand with particular receptors as well as…
Q: How does the function of an intracellular receptor differ from that of a membrane receptor? a. The…
A: The chemical structures composed of proteins that receive and transduce signals are called the…
Q: Compare and contrast receptors associated with polar and nonpolar signaling molecules.
A: Receptors are the molecules of proteins in the target cell on the surface of the cell. There are two…
Q: Amplification of a chemical signal occurs when? a. phosphorylation of proteins by protein kinase…
A: Receptors are usually proteins , which are present on the cell membrane, which binds to the ligand…
Q: Nitric oxide produced by the endothelial layer of blood vessels stimulates the smooth muscle layer…
A: The ability of internal communication was established from protista group. In course of evolution,…
Q: The receptors for steroid hormones and peptide hormones are fundamentally different because a. of…
A: Hormone Hormones are the body's chemical messenger that carry signal from one part of the body to…
Q: This question pertains to membrane transport and cell signaling. What are kinases and phosphatases?…
A: Cell signaling pathway is an important biological process that involves as a series of reactions.…
Q: Discuss the validity of the following proposition. A signaling molecule (hormone, growth factor, or…
A: Yes, it is definitely true that if different types of target cells have the presence of similar…
Q: List the ions that contribute to electrical signaling in neurons and what side of the neuron their…
A: Nerve cells also called neuron communicate by generating electric signal ans also through the…
Q: choose one: a. Steroids are hormones processed by their target cells at the plasma membrane b.…
A: The chemical messengers that are synthesized in one tissue and passed to one or other tissues…
Q: What is the function of a phosphatase? a. A phosphatase removes phosphorylated amino acids from…
A: Amino acids can be defined as the structural units that is known as monomers that make up the…
Q: Why is the lifetime of second messengers so crucial to signaling efficiency? Example: Genetically…
A: Secondary messengers act as mediators of information between cell-surface receptors and effector…
Q: Define the following terms: a. G protein-coupled receptor kinase b. β-arrestin c. enzyme-linked…
A: G protein-coupled receptor kinases are protein kinases.
Q: To examine: Whether the statement "most intracellular signaling pathways provide numerous…
A: Cell signalling, also known as cell-cell communication, is responsible for directing the basic…
Q: Which type of receptor is the insulin receptor? Select an answer and submit. For keyboard…
A: Answer: b. Protein kinase receptor.
Q: A function of the second messenger IP3 is to ... a) bind to and activate protein kinase A. b) bind…
A: Introduction:- There are three steps of cell signalling. 1. Reception: A signalling molecule from…
Q: The figure below shows the processes that occur during vision. Answer the following questions with…
A: Introduction: Membrane receptors are protein molecules that bind to or insert themselves into the…
Q: Explain Signaling by Receptors That Are Ligand-Gated Ion Channels?
A: Signal transduction (also known as cell signalling) is the transmission of chemical messages from…
Q: If your sepharose beads are covalently attached to adrenaline hormone, which of the following…
A: Affinity chromatography is a biochemical technique which is used to separate molecules based on the…
Q: The binding of a signaling molecule to its receptor will trigger a series of chemical reactions…
A: The cell in our body has various receptors on the surface of its cell membrane. These receptors can…
Q: A
A: Introduction :- The ability of cells to communicate through chemical signals originated in single…
Q: As an intracellular messenger molecule, explain the role of Ca2+ ion? (( cell signaling book ,…
A: Secondary messengers are defined as the small intracellular signaling molecules that play a major…
Q: Match the following description of a cell signal with signa A. signals across gap junctions 3.…
A: Match the following description of cell with signal type 1. Signal across gap junctions: Direct…
Q: Which of the following is incorrect about protein kinase A (PKA)? It is activated by the 2nd…
A: Protein Kinase A is a type of enzyme that can phosphorylate the serine or threonine residues of…
Q: Which of these is NOT a second messenger molecule? a. inositol triphosphate b. cyclic guanine…
A: Ans : K+ ions are not second messenger. option d is the right answer.
Q: Describe what cell signal activation is and how it occurs
A: Cell signaling is also known as a cell to cell communication. It co-ordinates multiple actions of…
Q: Explain how each of the following is a signaling molecule, an effector molecule or an adaptor…
A: Introduction :- Ligands, a broad name for compounds that bind selectively to other molecules, are…
Q: Which is correct?a. cAMP-dependent protein kinase phosphorylates tyrosine residues.b. Protein kinase…
A: The signaling molecules are involved in causing molecular level changes in the cells that bring…
Q: Carbon monoxide is a deadly gas. This is due to its quick activation of specific signaling pathways…
A: CO stands for carbon monoxide. It is a deadly gas which will bind to hemoglobin and reduces the…
Q: Histamine is a chemical substance released in inflammatory and allergic response. The histamine H1…
A: H1 receptors which gets activated by histamine is generally present in heart, CNS (central nervous…
Q: Define the following terms at least 5 related contents included. 1. Cell signaling 2. Intracellular…
A: All the terms mentioned in the question are related to signalling pathways related to cell to cell…
Q: Explain why different types of cells may respond differently to the same chemical messenger.
A: Any compound that transmits a message is referred to as a chemical messenger. Hormone is a chemical…
Q: Compare three types of signaling molecules: neurotransmitters, hormones, and local regulators.
A: Cell signaling is the process in which cell communicates with other cell with the help of signals.…
Q: Describe the biochemical signaling steps by which activation of the NMDA receptor causes the…
A: NMDA receptors (NMDARs) are glutamate-gated cation channels with high calcium permeability that are…
Q: What is the mechanism of organophosphate toxicity? A. Interference with the vesicle fusion process…
A: Organophosphates are the class of organophosphorus compounds that have the general structure…
Q: Insulin is a hormone that regulates blood sugar by binding to its receptor, insulin receptor…
A: Insulin is a hormone produced by the pancreas, a gland beneath the stomach. Insulin enables the body…
Q: Loss of insulin sensitivity is an example of which aspect of cellular signal transduction?…
A: Signal modification is a process in which the binding of an external cell to the cell surface…
Q: What leads to the activation of protein kinase C?a) Release of intracellular Ca+2 + diacylglycerolb)…
A: Cells generally communicate with the help of signals. The signals are chemical that can be a protein…
Q: You are working in a lab to examine the cellular responses to a new drug. You treat cells with the…
A: Based on their solubility, signaling molecules can be classified into two types. They are…
Q: The figure below shows a signaling pathway activated by the binding of ådrenáline to the…
A: GPCR or G protein coupled recepetor is a 7 pass transmembrane receptor on cell surface. B adrenergic…
Q: The single largest category of receptor type in Animal Cells is A. Enzymatic receptors B. G protein…
A: Receptors are proteins, cell surface receptors, that bind to ligands and lead to responses in the…
Q: Compare and contrast the receptors and signalling cascade, and the physiological roles for two…
A: * Neurotransmitters are the chemical messengers of the body which are used by the nervous system to…
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- 1. What cellular event happens in response to the binding of a growth factor to its respective receptor on the membrane of the growth factor’s target cell? Describe what happens to a tyrosine kinase receptor once it binds the growth factor signal. 2. Describe the three domains of a receptor tyrosine kinase. Explain the structure of the transmembrane domain and the amino acid composition and arrangement of this part of the receptor PLEASE ANSWER BOTH9. Consider the signal transduction pathway above. Label the following components of the pathway: ligand, receptor, secondary messengers, protein kinase, amplification 10. What is the specific name of the molecules that are serving as secondary messengers in the signal transduction pathway above? a. What is the role of secondary messengers? b. Name one other substance known to function in this capacity1. Based on the following description, draw the cell signaling pathway described (you only need to draw the pathway in one cell, but show the type of signaling described – you may need 2 diagrams). Compound X is released from cells in the pancreas and activates cells in the liver. What general type of cell signaling is this? When compound X binds its receptor on a liver cell, some of the amino acids (Y – one letter amino acid code) on the cytoplasmic side of the receptor are phosphorylated. Label what type of receptor this is. This leads to the receptor activating a cytoplasmic protein F which then activates a kinase K which then activates protein Z (diagram what is happening here – how is protein Z activated). Protein Z activation results in several genes being expressed. Label all your parts (don’t forget to label the ligand). Circle the signal transduction pathway and put a box around the cell response.
- 7. Fill in the table below, outlining different aspects of glutamate singlaing in the mammalian brain. A legend of possible entries is provided below the table, specifically for the columns "marker genes", “associated G proteins" and "ionotropic targets" Marker gene Ionotropic receptors Possible associated G proteins Gs Gą G₁/Go Possible marker genes: Choline acetyltransferase Solute carrier family 17 Glutamate decarboxylase Dopamine ß hydroxylase Possible ionotropic targets: Cayl channels Cav2 channels GIRK channels M-type K¹ channels BK channels SK channels Metabotropic Associated receptors G protein mGluR 1,5 mGluR 2-4,6-7- Pre- or post- Ionotropic Neuronal effects synaptic action? target(s) Tryptophan hydroxylase 2 Tyrosine hydroxylase Histidine decarboxylaseA. Signal transduction in cells can happen in two fundamental ways once a signal arrives at the cell membrane. Using diagrams to aid your explanations, compare these two different types of signal transduction and explain why they occur differently. How is the signal amplified and briefly describe the kinds of cell responses (at least 4) that can occur in cells.1. A mutation was introduced to the active site of the enzyme in a receptor tyrosine kinase so that it remains active in the absence of a substrate. What is the effect of this mutation on the signal transductionpathway?A. The phosphatase activity of the enzyme will be activated which will lead to receptor dimerization and subsequent cellular response.B. The signal molecule will bind to the receptor and dimerization will occur but the subsequent cellular response will be inhibited.C. The signal molecule will bind to the receptor but dimerization and subsequent cellular response will be inhibited.D. The signal molecule will bind to the receptor which will then triggers receptor dimerization and downstream cellular response. 2. Which of the following is not an advantage of non-coding regions of DNA?A. Some of these regions contain inactivated genes that can be reactivated upon insertion of regulatory sequences by mobile DNA elements.B. Some of these regions protect eukaryotic DNA from…
- 1a. Contrast the activation of cytokine receptors to the activation of receptor threonine kinases. b. We discovered a new cytokine that stimulates cancer cell growth. Now we want to determine if the JAK/STAT pathway is activated after stimulation. In the lab we have a small molecule that can competitively bind to SH2 domains. Explain where and how in the pathway this inhibitor would be effective.a. Name the phosphoinositide generated through the action of PI-5 kinase. b. Name the products generated by lipase action of the answer in a and specify which is hydrophobic and which is hydrophilic. c. Name the enzyme specifically responsible for the action described in b. d. Name the channel on the endoplasmic reticulum that is activated by the hydrophilic product listed in b. e. Name a protein activated by the hydrophobic product described in b.1. The four steps in the signal transduction pathway are listed below, a-d. Label the diagram above with the letters a-d to indicate where on the diagram each step is taking place, and answer the two questions below. a. Signal transmission i. Describe what is taking place during the signal transmission step. b. Reception i. Describe what is taking place during the reception step. Be sure to use the terms ligand, receptor, and target cell. C. Signal transduction d. Response
- Find all of the following Cell signalling pathway involved in alcohol: 1. Signal mechanism (what is the ligand?) 2. Type of receptor 3.Basic of signal transduction pathway 4. Specific of cellular response and organismal response.1a) Create a diagram which illustrates the typical signaling mechanism of action G protein-coupled receptors and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can for a novel pathway.Please answer with a drawing format by hand. 1. Based on the following description, draw the cell signaling pathway described (you only need to draw the pathway in one cell, but show the type of signaling described - you may need 2 diagrams). Compound X is released from cells in the pancreas and activates cells in the liver. What general type of cell signaling is this? When compound X binds its receptor on a liver cell, some of the amino acids (Y - one letter amino acid code) on the cytoplasmic side of the receptor are phosphorylated. Label what type of receptor this is. This leads to the receptor activating a cytoplasmic protein F which then activates a kinase K which then activates protein Z (diagram what is happening here - how is protein Z activated). Protein Z activation results in several genes being expressed. Label all your parts (don't forget to label the ligand). Circle the signal transduction pathway and put a box around the cell response. THIS IS A TOTALLY MADE-UP…