A student properly sets up a column chromatography experiment. Although the mixture is soluble in the mobile phase, the sample appears "stuck" at the top of the column and will not elute regardless of how much solvent is applied. What could be the cause of this prob lem and what could the student do to try and achieve a successful separation?
A student properly sets up a column chromatography experiment. Although the mixture is soluble in the mobile phase, the sample appears "stuck" at the top of the column and will not elute regardless of how much solvent is applied. What could be the cause of this prob lem and what could the student do to try and achieve a successful separation?
Chapter88: Column Chromatography
Section: Chapter Questions
Problem 1P
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A student properly sets up a column chromatography experiment. Although the mixture
is soluble in the mobile phase, the sample appears "stuck" at the top of the column and will
not elute regardless of how much solvent is applied. What could be the cause of this prob lem and what could the student do to try and achieve a successful separation?
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