b. Consider the following five-membered heterocycles: i. ii. iii. iv. V. vi. vii. B C Which of them is the most reactive in electrophilic substitution? Explain Which of them is the least reactive in electrophilic substitution? Explain Which heterocycle; B or C, contains the most acidic N-H proton? Explain. Predict the site of electrophilic substitution in heterocycle B. Explain Which is the most aromatic? Explain Which of them is capable of hydrogen-bonding? No explanation required Which of them contains the most acidic C-H? Explain. E

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter15: Benzene And Aromaticity
Section15.SE: Something Extra
Problem 37AP
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b. Consider the following five-membered heterocycles:
i.
ii.
iii.
iv.
V.
vi.
vii.
N
B
C
D
Which of them is the most reactive in electrophilic substitution? Explain
Which of them is the least reactive in electrophilic substitution? Explain
Which heterocycle; B or C, contains the most acidic N-H proton? Explain.
Predict the site of electrophilic substitution in heterocycle B. Explain
Which is the most aromatic? Explain
Which of them is capable of hydrogen-bonding? No explanation required
Which of them contains the most acidic C-H? Explain.
E
Transcribed Image Text:b. Consider the following five-membered heterocycles: i. ii. iii. iv. V. vi. vii. N B C D Which of them is the most reactive in electrophilic substitution? Explain Which of them is the least reactive in electrophilic substitution? Explain Which heterocycle; B or C, contains the most acidic N-H proton? Explain. Predict the site of electrophilic substitution in heterocycle B. Explain Which is the most aromatic? Explain Which of them is capable of hydrogen-bonding? No explanation required Which of them contains the most acidic C-H? Explain. E
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