Carbachol causes contractions the isolated rat ileum to contract. The responses obtained to increasing concentrations of carbachol are tabulated below. Graph the data as log concentration versus % maximum response, using Excel or another spreadsheet program. Use the graph to estimate the EC50 value for carbachol and indicate its position on the graph. Conc (M) Exp 2 (% max response) Exp 1 Exp 3 (% max response) (% max response) 1.00E-09 3.00E-09 10 9. 20 1.00E-08 45 35 48 3.00E-08 57 69 72 1.00E-07 74 81 91 3.00E-07 95 85 96 1.00E-06 100 100 99 3.00E-06 100 98 99

Carbachol causes contractions the isolated rat ileum to contract. The responses obtained to increasing concentrations of carbachol are tabulated below. Graph the data as log concentration versus % maximum response, using Excel or another spreadsheet program. Use the graph to estimate the EC50 value for carbachol and indicate its position on the graph. Conc (M) Exp 2 (% max response) Exp 1 Exp 3 (% max response) (% max response) 1.00E-09 3.00E-09 10 9. 20 1.00E-08 45 35 48 3.00E-08 57 69 72 1.00E-07 74 81 91 3.00E-07 95 85 96 1.00E-06 100 100 99 3.00E-06 100 98 99

Fundamentals Of Analytical Chemistry

9th Edition

ISBN:9781285640686

Author:Skoog

Publisher:Skoog

Chapter16: Applications Of Neutralization Titrations

Section: Chapter Questions

Problem 16.10QAP

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