Carbon dioxide is dissolved in blood (pH 7.5) to form a mixture of carbonic acid and bicarbonate. Part A Neglecting free CO2, what fraction will be present as carbonic acid? (pKa for H₂CO3 and HCO3 are 6.3 and 10.25, respectively) Express your answer using two significant figures.
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- Carbon dioxide is dissolved in blood (pH 7.4) to form a mixture of carbonic acid and bicarbonate. Neglecting free CO2, what fraction will be present as carbonic acid? Would you expect a significant amount of carbonate (CO32-)?Which of the equations below best represents how excess acid in the blood plasma can be removed in the lungs by breathing? H+ (aq) + 0. 2(g) OH + H₂ CO (aq) OH+ + O (aq) 2(g) → H, CO. H + O₂ (aq) 2(g) 3(aq) 3(aq) → H₂O(g) + CO2(g) + CO2(g) → H₂O H, CO3(aq) → HCO, OH t + HCO3(aq) → H₂ CO3(g) → H₂O(g) (aq) → H, CO3(aq) 3 (aq) + CO2(g) H₂O(g) + CO2(g)Carbon dioxide is dissolved in blood (pH 7.4) to form a mixture of carbonicacid and bicarbonate. Neglecting free CO2, what fraction will be present as carbonic acid? Would you expect a significant amount of carbonate (CO32-)?
- Human blood has a pH of approximately 7.4 due to the carbonic acid/bicarbonate ion (H2CO3/HCO3−) buffer system. Any pH changes below 6.8 or above 7.8 can lead to death! Carbonic acid dissociates to form water and carbon dioxide in the equilibrium shown below. This process is crucial in respiration.H2CO3 (aq) ⇋ CO2 (g) + H2O pKa1 = 2.77 Carbonic acid dissociates in water to form the bicarbonate ion and the hydroxonium ion by the following equilibrium reaction:H2CO3 (aq) + H2O ⇋ H3O(aq)+ + HCO3− pKa2 = 3.70 (ii) Explain how a 25% increase in carbonic acid levels may impact the availability of lead if a tainted calcium supplement ends up on the local marketCarbonic anhydrase is an extremely efficient enzyme in red blood cells that performs the essential function of trapping C02 coming out of tissues and hydrating it with H,0. The product of this reaction is which dissociates into a proton and a (Hint: the reaction is H20 + CO2 +„H+ bicarbonate; carbonic acid carbonic acid; carbonate carbonate; carbonic acid carbonate; bicarbonate carbonic acid; bicarbonateSketch a diagram of an oxygen dissociation curve indicating the following pH values 7.0, 7.2, 7.4, 7.6 and 7.8 on it.
- Calculate the pH of a blood plasma sample with a total CO2 concentration of 26.9 mM and bicarbonate concentration of 25.6 mM. Recall from page 67 that the relevant pK2 of carbonic acid is 6.1Given the oxygen dissociation curves, which of the following statements are correct? Which residue in HbA β do you think contributes the most to the increased interaction between HbA aand 2,3‑BPG?If normal plasma pH is 7.4 and normal [CO2) is 1.2 mM, what is the normal (HCO321? The pK9 for this system is 6.1. Phosphoric acid (H3PO4) has three dissociable protons, with the pK,'s shown below. Which form of phosphoric acid predominates in a solution at pH 4? Explain your answer. Acid H3POA 2.14 H2PO4 6.86 HPO,2- 12.4
- Calculate the pH of a blood plasma sample with a total CO₂ concentration of 25.7 mM and bicarbonate concentration of 24.4 mM. The relevant pK, of carbonic acid is 6.1. Enter the answer with three significant figures. pH =The normal concentration of Ca2+ in blood is 5.0 mEq>L. How many milligrams of Ca2+ are in 1.00 L of blood?How many liters of dry hydrogen gas, measured at 798 mmHg and 21C, will be released by the decomposition of 230 mL of H20 at 1.42atm and 30C? 2 H20 (g) → 2 H2 (g) + O2 (g) Answer to 3 decimal places. Your Answer: Answer units