Cimetidine was the first H2 antagonist in anti-ulcer therapy in the 1960s. The development of cimetidine was inspired by the fact that histamine stimulates gastric acid release in vitro. Which drug design strategy was used in the development of cimetidine: O Fragment based screening O X-ray crystallography O Rational drug design O Molecular modelling

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 7.7P
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Cimetidine was the first H2 antagonist in anti-ulcer therapy in the 1960s. The development of
cimetidine was inspired by the fact that histamine stimulates gastric acid release in vitro. Which drug
design strategy was used in the development of cimetidine:
O Fragment based screening
O X-ray crystallography
O Rational drug design
O Molecular modelling
Transcribed Image Text:Cimetidine was the first H2 antagonist in anti-ulcer therapy in the 1960s. The development of cimetidine was inspired by the fact that histamine stimulates gastric acid release in vitro. Which drug design strategy was used in the development of cimetidine: O Fragment based screening O X-ray crystallography O Rational drug design O Molecular modelling
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