Clinical Use of Opioid Drugs Ms Smith is admitted to hospital for renal colic. Upon admission, she is charted the following oral medications for pain: Route PO PO Dose and Frequency 1 tablet twice daily Oxycodone 5 mg immediate release 1-2 tablets up to every 4 hours tablets (Endone) when needed Drug Oxycodone 10 mg controlled release tablets (OxyContin) Question: Explain why the two medications are dosed at different frequencies despite both containing oxycodone, providing a pharmacokinetic and clinical rationale for the prescriber's decision. Assume that the dose and frequency of administration are appropriate. (150 words)

Comprehensive Medical Terminology
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Chapter20: Radiology And Diagnostic Imaging
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Clinical Use of Opioid Drugs
Ms Smith is admitted to hospital for renal colic. Upon admission, she is charted the following oral medications for pain:
Route
PO
PO
Drug
Oxycodone 10 mg controlled release
tablets (OxyContin)
Dose and Frequency
1 tablet twice daily
Oxycodone 5 mg immediate release 1-2 tablets up to every 4 hours
tablets (Endone)
when needed
Question: Explain why the two medications are dosed at different frequencies despite both containing oxycodone, providing a
pharmacokinetic and clinical rationale for the prescriber's decision. Assume that the dose and frequency of administration are
appropriate. (150 words)
Transcribed Image Text:Clinical Use of Opioid Drugs Ms Smith is admitted to hospital for renal colic. Upon admission, she is charted the following oral medications for pain: Route PO PO Drug Oxycodone 10 mg controlled release tablets (OxyContin) Dose and Frequency 1 tablet twice daily Oxycodone 5 mg immediate release 1-2 tablets up to every 4 hours tablets (Endone) when needed Question: Explain why the two medications are dosed at different frequencies despite both containing oxycodone, providing a pharmacokinetic and clinical rationale for the prescriber's decision. Assume that the dose and frequency of administration are appropriate. (150 words)
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