Consider a gene that where a disease-causing low-frequency recessive allele is segregating in the population. This would be similar to the case of cystic fibrosis. Assume standard genetic nomenclature where the wildtype allele occurs at frequency p and the disease-allele occurs at frequency q. What is the correct calculation to find the probability that a single healthy individual is a carrier for the disease allele? (Hint: You want the chance of being a heterozygote divided by the chance of being a healthy person) O p? + q? O p-4 O (1-q³)/2pq 2pq/(1-q°) q°/2pq
Consider a gene that where a disease-causing low-frequency recessive allele is segregating in the population. This would be similar to the case of cystic fibrosis. Assume standard genetic nomenclature where the wildtype allele occurs at frequency p and the disease-allele occurs at frequency q. What is the correct calculation to find the probability that a single healthy individual is a carrier for the disease allele? (Hint: You want the chance of being a heterozygote divided by the chance of being a healthy person) O p? + q? O p-4 O (1-q³)/2pq 2pq/(1-q°) q°/2pq
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Consider a gene that where a disease-causing low-frequency recessive allele is segregating in the population. This would
be similar to the case of cystic fibrosis.
Assume standard genetic nomenclature where the wildtype allele occurs at frequency p and the disease-allele occurs at
frequency q.
What is the correct calculation to find the probability that a single healthy individual is a carrier for the disease allele?
(Hint: You want the chance of being a heterozygote divided by the chance of being a healthy person)
p? + q?
p- 4
(1-q?)/2pq
2pq/(1-q²)
q°/2pq
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