Describe how genetic influences of quantitative traits can be studied in humans. Describe some of the types of studies and why they are helpful. Answer in at least 4 full sentences.
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Describe how genetic influences of quantitative traits can be studied in humans. Describe some of the types of studies and why they are helpful. Answer in at least 4 full sentences.
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- Explain how a Lod score is obtained and whatinformation it provides.Answer in less than 30 words:Why are mathematical /statistical tools needed in the understanding of the transmission of traits in the field of Genetics?A geneticist is studying memory recall and is trying to locate specific genes that have varying effects on a given phenotype (physical trait) in the study subjects. These locations of these genes are referred to as: Group of answer choices Genomic spatial identifications Epigenetic regulators Evocative response indicators Quantitative trait loci
- Elaborately define the major considerations in dosage form design with example? Please briefly answer at your own easy words.Identify a possible advantage and a possible disadvantage of a genetic test that would identify genes in individuals that increase their probability of having Alzheimer’s disease later in life.Explain how you will provide genetic testing information to insurance companies. Be sure to support your argument with specific examples and logical reasoning.
- Select all the characteristics that make sickle-cell disease a good candidate to study genetic diseases. (Check all that apply.) Check All That Apply It is easily identifiable by a physical characteristic.It is easily identifiable by a physical characteristic. It results from a single change in a single gene.It results from a single change in a single gene. It can be influenced by the environment.It can be influenced by the environment. The sickle-cell inheritance pattern is not influenced by other genes.The sickle-cell inheritance pattern is not influenced by other genes.What are the importance of dosage forms? Explain your answerBriefly explain how genes affecting a polygenic characteristic are located with the use of QTL mapping.
- What is the primary reason for randomizing group allocation in a randomized controlled trial (RCT)? Question 3 options: to create treatment and control groups of equal size to blind participants to their group allocation to evenly distribute known and unknown factors that may affect the outcome between groups to increase the treatment effect between intervention and control groupsMatch the following : Genetic testing Genetic screening Genetic screening programs Genetic screening opportunities A test with high senstivity A test with high specificity predictive tests Pre- symptomatic tests Pre dispositional test involves testing individuals for the genetic change underlying a condition for which there is no evidence. can show that an individual is more likely than others to develop a specified condition. indicate the presence of a causative genotype but the onset of signs and symptoms is not certain. are offered as part of our public health service. do not include conditions that show incomplete penetrance. is performed cases where the onset of signs and symptoms is considered inevitable. involves testing individuals for the genetic change underlying a condition for which there is evidence. has a low false positive rate has a low false negative rateEvaluate the complexity of the technical issues related to managing and utilizing genomic data as discussed in chapter 24. Without discrimination as the framework, preventive medicine and wellness models may desire genetic testing in adults to identify genetic diseases before they cause symptoms. Outline the considerations for the shifts in health care delivery caused by personalized medicine including the management of personalized data.