Describe what happen in each step as specific as possible. 1. What is La Chatelier ‘s principle?how it contribute to Fischer Esterification? 2. Explain the mechanism ,what happen in each reaction?

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter20: Carboxylic Acids And Nitriles
Section20.2: Structure And Properties Of Carboxylic Acids
Problem 4P: The Ka for dichloroacetic acid is 3.32 Ă— 10-2. Approximately what percentage of the acid is...
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Describe what happen in each step as specific as possible. 1. What is La Chatelier ‘s principle?how it contribute to Fischer Esterification? 2. Explain the mechanism ,what happen in each reaction?
Fischer Esterification.
utilizes La chatelier's principle to shift the
equilibrium.
CH3CO
acetic acid
Mechanism
OH
CH3-C=0.
product
CO=C
:Ö
YOH
CH₂-C-ÖR
+ H₂SO4
+
мон
isopentyl alcohol
(bad smell)
24
H2804
: H
ITS
CH3-C-OH
1804
HSO4 +
CH3-C-ÖR
:O:
H TH
=0
CH3-C
isopentyl acetate
-H
0.
CH3-C-OH
Loss of
H₂0
X
alcohol
+4₂0
0-0-0:
+0:3
:9-H
CHS-C-OH
R-O:
11
H
CH₂-CH
alic
H
e
intramole
transfor
C
Transcribed Image Text:Fischer Esterification. utilizes La chatelier's principle to shift the equilibrium. CH3CO acetic acid Mechanism OH CH3-C=0. product CO=C :Ö YOH CH₂-C-ÖR + H₂SO4 + мон isopentyl alcohol (bad smell) 24 H2804 : H ITS CH3-C-OH 1804 HSO4 + CH3-C-ÖR :O: H TH =0 CH3-C isopentyl acetate -H 0. CH3-C-OH Loss of H₂0 X alcohol +4₂0 0-0-0: +0:3 :9-H CHS-C-OH R-O: 11 H CH₂-CH alic H e intramole transfor C
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