different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.) in ensuring the safety of a drug candidate. Briefly explain this at your own words

Q: What is more preferred for drug therapy, conventional or modified release dosage forms?

A: Drug therapy is the process of treating illness with the help of drugs (medicine)  Conventional drug…

Q: drug therapy, conventional or modified release dosage forms

A: Most conventional (immediate release) oral drug products, such as tablets and capsules, are…

Q: Explain the role of LC50 in ensuring the safety of a drug candidate? Explain at your own words

A: Drugs are defined as the type of chemical substances where they produce changes in the physiology or…

Q: Carbon monoxide binds to the active site of hemoglobin and inhibits the binding of oxygen. This is…

A: An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity. By binding to…

Q: Explain the role of  toxicological parameters LD50 in ensuring the safety of a drug candidate.…

A: Toxicological parameters - It is the level of toxicity to determine drug usage. The toxicological…

Q: Describe the significance of the use of pharmacokinetic parameters in case to calculate appropriate…

A: Pharmacokinetics is the study of a drug that is administered to a living Organism which describes…

Q: Lead discovery - Target selection - Medicinal chemistry - In vitro studies - In vivo studies -…

A: THR DRUG DEVELOPMENT PROCESS There are 5 processes of drug development. 1. Drug discovery and…

Q: Antimicrobial Effectiveness Tesct (AET)  is called differently  in European Pharmacopeia and…

A: Answer : In Antimicrobial Effectiveness Test(AET) is called differently in European Pharmacopeia is…

Q: In the dose response curve below, Drug B has [ Select ] * potency and [ Select ] efficacy as Drug A

A: Efficacy and potency are two characteristic features of a drug, which shows how effective and potent…

Q: What is the importance of the specialist in the analysis of the results obtained by QSAR models of…

A: A specialist is a person that specializes in a particular field of study or are experts in their…

Q: What are the different component of therapeutic index. Define its clinical relevance

A: therapeutic index: The dosage range at which a medicine is effective without causing unacceptably…

Q: Explain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.)…

A: A drug is any substance that can affect psychology or physiology when taken into the body. It is…

Q: Discuss the factors governing the route of drug administration with examples.

A: The reason for option of routes of medication administration are governing by many factors:…

Q: What would you prefer for drug therapy, conventional or modified release dosage forms?

A: Most conventional (immediate release) oral drug products, such as tablets and capsules, are…

Q: What knowledge can be gained from dose-response relationships?   Why are the shape and slope of a…

A: Drug dose response relationship suggests that what type of drug arouses what kind of response.…

Q: Explain the concept of selective toxicity in terms ofantimicrobial therapy.

A: The antimicrobial drug helps in eliminating the pathogenic microorganism from the host body cells…

Q: Pick a pathogen, suggest tests that should be performed on that pathogen to determine the specific…

A: In a living organism, infection tends to occur with invasion, growth, and reproduction of…

Q: When two antimicrobial drugs are used at the same time, antagonistic effects can occur. Which of the…

A: When two or more drugs are used together, there happens to be some interactions between the drugs…

Q: Name at least five requirements for a drug to exert its biologic action

A: A drug is a chemical agent that influences the biological system in a possibly useful manner. The…

Q: Two different methods are described in the literature to portray the pharmacokinetics of ethanol.…

A: Alcoholic beverages are part of several cultures since the beginning of human civilization. Our…

Q: Which of the following statements applies to a drug with low therapeutic index? Select one: It is…

A: NOTE: The options are numbered as 1, 2, 3 and 4.  Toxicology is the study of the drugs or chemical…

Q: categorize the following into reversible or irreversible (competitive or non-competitive)…

A: Introduction: Irreversible inhibitor:  It blocks the enzyme by covalently binding to it at the…

Q: Discuss the toxicological effects of un-intentional by-product on plant, animals and human being?

A: Hexachlorobenzene (HCB) was used as a seed-dressing for crops to stop fungal illness. it's used as…

Q: 1.- Please name the drug sources, and explain one of them. 2.- Why are important the Drug Standards?…

A: (NOTE: Since student have not mention the specific question to answer, only the first three subparts…

Q: Explain the major mechanisms by which microbes becomeresistant to drugs.

A: Antimicrobial resistance refers to the condition that occurs when microorganisms such as bacteria,…

Q: What are the advantages of inhalation drug delivery systems over other routes of drug administration…

A: The inhalation route is used for the local treatment of pulmonary diseases. In the management of…

Q: ake a drug study with 6 columns. It should include the following: FIRST COLUMN - Generic name,…

A: (NOTE : Since the student have not mention about the specific subpart to be answered, only the first…

Q: What is Therapeutic Drug Monitoring (TDM) and under what circumstances would it be considered for a…

A: Therapeutic drug monitoring (TDM) is commonly described because the medical laboratory size of a…

Q: Choose the correct one, Which is the useful pharmacokinetic parameter that provides an accurate…

A: Many of the factors are mainly responsible for influencing drug efficacy. One such important factor…

Q: Identify the general categories of the cellular targets of physical and chemical agents.

A: A cell is the basic unit of life that eventually assembles into a whole creature. A cell contains a…

Q: Describe the factors that affect both drug absorption and bioavailability.

A: Drug absorption : The most important principle in pharmacokinetics theory is drug absorption. The…

Q: At therapeutic range, theophylline follows linear pharmacokinetics. The average t1/2 is 3.4 hours,…

A: Half life time (t1/2) is referred to as the time taken to reduce concentration of a drug to half of…

Q: Name some pharmacology math conventions that have been instituted to keep patients safer.

A: Mathematics always plays a vital role in most sectors of society. In the field of nursing and…

Q: Draw and explain the conceptual pathway of mechanism, transport and excretion of drugs. (subject:…

A: In pharmacology, drugs are defined as chemical substances or compounds used as medicines, which…

Q: How to minimize the response flactuation from levodopa therapy? Please answer at your own easy…

A: Levodopa therapy is used to treat patients with Parkinson's disease. It is a disease in which…

Q: Discuss the study of chemical hazards and their effects,including wildlife toxicology, epidemiology,…

A: Toxicants can be both organic and manmade, and there are hundreds of synthetic compounds in our…

Q: According (https://www.ncbi.nlm.nih.gov/books/NBK326791), a biomarker is used to show that a…

A: Biomarkers:-Also known as a biological marker.-It is defined as a characteristic that is measured…

Q: Explain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.)…

A: In the development of new drug it is very important to make sure about its safety. After the invitro…

Q: Select the best example of irreversible inhibitors. i. Cyanide ii. Ibuprofen iii. Arsenic iv.…

A: Answer - B. i, iii and iv # Example of irreversible inhibitor is a metabolic poison --- potassium…

Q: Choose the combination of answers that most accurately completes the statement. An antimicrobial…

A: The therapeutic index refers to the ratio that is used to quantitatively measure the relative safety…

Q: Explain the role of  toxicological parameters LOAEL in ensuring the safety of a drug candidate.…

A: In the development of a new drug, it is very important make sure about the safety profile of the…

Q: What drug characteristics are most important to consider in therapy?

A: Several drug formulations are given to patients whenever their body experiences any pathogenic or…

Q: How we can identify the drug-drug interaction and how can it be prevented? explain

A: Drug interactions occur when one drug alters the pharmacological response of other drug. The…

Q: Penicillins and aminoglycosides are not allowed to be administered in the same solution before…

A: NOTE: The options are numbered as 1, 2, 3, and 4.  Penicillin is a beta-lactam antibiotic and is…

Clinical Pharmacology

Pharmacology is a discipline of medicine that studies how medications interact with the systems and processes of living organisms, focusing on drug action mechanisms as well as therapeutic and other purposes.