Drug X is a weak acid with a pk of 3.4. The deprotonated (base) form is active and the protonated (acid) form is inactive. What percentage of Drug X will be in the active form in the upper intestine (pH = 3.8)?

Drug X is a weak acid with a pk of 3.4. The deprotonated (base) form is active and the protonated (acid) form is inactive. What percentage of Drug X will be in the active form in the upper intestine (pH = 3.8)?

Chemistry: The Molecular Science

5th Edition

ISBN:9781285199047

Author:John W. Moore, Conrad L. Stanitski

Publisher:John W. Moore, Conrad L. Stanitski

Chapter15: Additional Aqueous Equilibria

Section: Chapter Questions

Problem 105QRT: Apatite, Ca5(PO4)3OH, is the mineral in teeth. On a chemical basis explain why drinking milk...

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11. Drug X is a weak acid with a pK of 3.4. The deprotonated (base) form is active and the protonated
(acid) form is inactive. What percentage of Drug X will be in the active form in the upper intestine (pH =
3.8)?

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