Explain in a more clinical detail the mode of actions of the following on the human skin cell or tissue: 3. Peptides and proteins 4. Retinoids 5. AHA/BHA
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Explain in a more clinical detail the mode of actions of the following on the human skin cell or tissue:
3. Peptides and proteins
4. Retinoids
5. AHA/BHA
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Solved in 3 steps
- Explain in a more clinical detail the mode of actions of the following on the human skin cell or tissue: 1. Free radicals 2. Anti oxidants 3. Peptides and proteins 4. Retinoids 5. AHA/BHAQuinolones and fluroquinolones affect cell membrane integrity? True or false.Describe the enzymatic reaction of the protein epidermal growth factor. Include the specific reaction catalyzed by the protein. Enzymatic reaction is a physiologically relevant biochemical stimulus for the temporal and spatial control of drug release because: (1) the overexpression of specific enzymes is localized at diseased tissues.
- A70-year-old woman with a long history of systemic lupus erythematosus has been receiving prednisone for the past 3 months. She also has been receiving captopril to treat her hypertension. Which of the following laboratory results would be evident in this patient? ???? ?????? ?? ????? ?? ???? ???????? a. Hyperglycemia b. Hyponatremia c. Hypercalcemia d. Hypocholesterolemia e. Hypokalemia4.A 65-year old man complains of an increasing resting tremor of hands, stiffness in muscles, a change in his gait. His wife noted anxiety and emotional lability. What diagnosis can be made?a)Concentration of what catecholamine in the neostriatum can lead to such symptoms? Name the desease.b) Write by formulasthe reactions ofsynthesis of this catecholamine and its degradation。 c)What drug therapy is used for treatment of this desease?14) Matt has given an oral drug drug. Before the drug takes its effect on the body it is partially metabolized by liver enzymes. Which of the following terms best describes this phenomenon? A) Pharmacokinetics B) First-Pass Effect C) Bioavailability D) Idiosyncracy 15) How would you best describe the Z-Track Method of IM Injection? A) Insert the needle at 15 Degrees, then when you reach the muscle turn it 30 Degrees B) Pull the tissue taut after inserting the needle C) Pull the tissue taut before inserting the needle D) Using a Z-Shaped needle
- GM is a 55 yo that just returned from visiting their sister in Arizona. They got a sunburn while out playing tennis and are seeking advice on how to manage their sunburn. The pharmacist looked at the patient's sunburn and gathered the following information from them: • NKDA (sensitive to adhesives and some topical anesthetics) • No current medications or medical conditions S - tightness and redness of the burnt skin without blistering; denies fever, chills, headache, or tiredness C - skin was only slightly pink yesterday, has turned deeper pinkish red today H - they haven't done anything to treat it so far O - burn appeared today (the morning after being outside) L - skin on their arms (just above elbow to wrist) and legs (midthigh to top of ankles) and back of neck where their tennis shirt and shorts did not adequately cover them; they were wearing a baseball hat and sunglasses. No burn present on face. A - mild pain especially when the skin is touched or brushes against clothes or…A 56 y/o woman has a history of extensive exposure to ultraviolet radiation from both the sun and artificial tanning sources( tanning lights&beds) since childhood. The excessive wrinkling observed is caused primarily by which one of the the following effects of UV rays on the skin? A)damaged elastic fibers B)dilated follicles with plugged orifices C)increased size and activity of melanocytes D)thickening of the the stratum Cornell E)vascular sclerosis of dermal blood vesselsIncreased blood pressure A) Epinephrine B) Isoproterenol C) Phenylephrine D) Physostigmine E) Tyramine Control Prazosin X Cocaine X Time 161. Drug X is injected intravenously into three subjects (including one control subject). The control subject is not pretreated, whereas the other two subjects are pretreated with either prazosin or cocaine. Blood pressure is recorded directly from the brachial artery (see graph). Drug X is most likely which of the following? 4 X
- Why is the use of first-generation H1-antihistamines discouraged in clinical practice today?3. 20-year-old George Tsakino stepped on a Lego® while helping his daughter Mina pick up her toys. The Lego® broke and pierced the sole of his foot. After a visit to the emergency department at the local hospital the Lego® pieces have been removed, and there is no danger of infection. George has been bandaged, but he is limping and still in some pain. The nurse practitioner has said that he can take acetaminophen for the pain. Acetaminophen is a medication that is taken by mouth but will act at the site of the pain (in this case, in the foot). It is absorbed by the blood vessels in the small intestine. Trace the pathway taken by the acetaminophen as it travels from the site of absorption to the site of the patient's foot pain. 4. Which four (or three) blood vessels empty into the hepatic portal vein? What is the function of the hepatic portal system, and why is this system important to homeostasis and protection of the body from its environment? 5. Congratulations, you've just…1. Why do physicians use local anesthetics that contain epinephrine when performing minor surgery, and what effect does the patient feel with this medication? 2. What conditions are necessary for absorbable sutures to be effective? 3. Why is it important for each surgical instrument to be carefully examined after each use and before sterilization?
