Please answer parts F and G. The previous parts have been answered with explanations. Only parts F and G need to be answered and explained. Please do so thoroughly and efficiently with clear explanations. 1. The peptide below was isolated from fermented milk andshown to have antioxidant propertiesLactobacillus delbrueckii subsp.,bulgaricus IFO13953N-Ala-Arg-His-Pro-His-Pro-His-Leu-Ser-Phe-Met-Ca) Draw the primary structure of the from the N-terminal to theC-terminal G. Make sure that the ends and the R groups are inthe ionization state that would be expected at biological pH=7.b) Place a box around each of the peptide bonds.c) Write the sequence using 1 letter abbreviations.d) What is the net charge of the peptide at pH=7? Calculate thepl.e) Draw the titration curve for the polypeptide and show wherethe pl and buffering regions are..f) Identify -R groups that:●Are hydrophobic, hydrophilic and aromaticAre the H-bond donors and acceptors by placing a d or ana by the appropriate atom• can take part in electrostatic interactions. For the R groupsthat are charged at pH=7, list the other possible charged Rgroups that would interact favorably with the chargedgroup in the peptide. (these should be chosen from the listof all common amino acids)9) Explain how the pKa of an amino acid can differ depending onits chemical environment, either aqueous or hydrophobic. Considerboth and acidic and basic amino acid in your explanation. (oneparagraph).

In the study of peptides and proteins, understanding their structural and chemical properties is…

f) Identify -R groups that: Are hydrophobic, hydrophilic and aromatic • Are the H-bond donors and acceptors by placing a d or an a by the appropriate atom • can take part in electrostatic interactions. For the R groups that are charged at pH=7, list the other possible charged R groups that would interact favorably with the charged group in the peptide. (these should be chosen from the list of all common amino acids) g) Explain how the pKa of an amino acid can differ depending on its chemical environment, either aqueous or hydrophobic. Consider both and acidic and basic amino acid in your explanation. (one paragraph).

f) Identify -R groups that: Are hydrophobic, hydrophilic and aromatic • Are the H-bond donors and acceptors by placing a d or an a by the appropriate atom • can take part in electrostatic interactions. For the R groups that are charged at pH=7, list the other possible charged R groups that would interact favorably with the charged group in the peptide. (these should be chosen from the list of all common amino acids) g) Explain how the pKa of an amino acid can differ depending on its chemical environment, either aqueous or hydrophobic. Consider both and acidic and basic amino acid in your explanation. (one paragraph).

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter9: Gene Expression And Gene Regulation

Section: Chapter Questions

Problem 15QP

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I was wondering if it is possible to provide an explanation on the structure of the PDB code 2V1X, the amino acid at position 219 and the mutation of the amino acid name LU. Thank you.
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Shown to the right is a cartoon image of ETC Complex I from Y. lipolytica. A group of authors studied this wild type Complex I and also a version where the arginine at position 121 in the chain 3 subunit was mutated to a methionine (R121M). Part of chain 3 subunit contains the peptide sequence SMITH a. Draw the titration curve for the SMITH peptide. Mark all pKa’s and the pI on your curve. For the SMITH peptide at physiological pH, explain what types of interactions you believe the side chains are or are not able to participate in.
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draw the structure of the peptide Asp - Asn-Ser-Lys-Pro at PH 8
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5'-TAGCTGATCGAATATGCGGTCTCTATCTTCGTAGACGA-3' 3'-ATCGACTAGCTTATACGCCAGAGATAGAAGCATCTGCT -5' Determine the amino acids that will be encoded by this sequence Second letter First letter U C A G U UUU Phe UUC UUA UUG Leu CUU CUC CUA CUG Leu GUU GUC GUA GUG Val UCU UCC UCA UCGJ AUU AUC lle AUA ACA AUG Met ACG CCU CCC C CCA CCG ACU ACC GCU GCC GCA GCG Ser - Pro Thr Ala A UGU UACTyr Cys UGC. UAA Stop UGA Stop A UAG Stop UGG Trp G CAC His CAA Gin CAG GAUT GAC Asp GAA AAU Asn ACC Ser AGU AAG LYS AA Glu GAGJ Oa. N-Met-Arg - Ser-Leu-Ser - Ser-C Ob. N-Met-Pro-Arg - Asn-Asp - Ser-C d. N-Met-Lys - Val-Glu-Ala-C Oc. N-Asp-Pro-Lys - Ser - Val-Ile-C Oe. N- Met-Ala-Asp-Pro-Lys - Ser-C G CGU CGC CGA CGG AGA AGG. GGU GGC GGA GGG Arg SCAO Gly U UCAG UUA DUAG Arg G Third letter 13