Given that the transgene used is only upregulated in the brain and spinal cord of TMFN mice, what might account for the TMFN mice having less severe cardiac dysfunction in response to LPS challenge?
Q: Describe five strategies that can be used to engineer resistance into crop plants. Which strategy do...
A: Introduction The main unit of study in agroecology is the agroecosystem, which is vaguely defined as...
Q: c) Outline the possible reasons for operating a sequential two stages system, instead of a single la...
A:
Q: What are the outline the major components of the core concept of cell-to-cell chemica communication
A: Introduction:- Chemical communications are constantly sent and received by cells in multicellular or...
Q: Describe some of the evidence that supports the binding change mechanism.
A: The ATP synthase enzyme, which is located in chloroplasts and mitochondria, exhibits a binding chang...
Q: In order to sexually reproduce, multicellular organisms utilize a process called ______. The type of...
A: Meiosis is defined as the key process of sexual cycle in eukaryotic organisms. In this process, a si...
Q: Kingdom: Animalia Phylum: Chordata Order: Dipnoi Suborder: Ceratodontoidei Family: Neoceratodontidae...
A: Neoceratodus forsterai is the only surviving lungfish species and is very old making it a living fos...
Q: Please match the tissue to the description. covers the ends of bones in a joint [ Choose ] [ Choose ...
A: Cartilage. This is a type of tissue that covers the surface of a bone at a joint. Cartilage helps re...
Q: Can you answer all the parts to this question regarding fish (please type the answer) Mammals hav...
A: Fish gills use a design called ‘countercurrent oxygen exchange’ to maximize the amount of oxygen tha...
Q: In dogs, dark coat color is dominant over albino, andshort hair is dominant over long hair. Assume t...
A: Hereditary qualities is the study of genes and heredity of how certain characteristics or attributes...
Q: health benefits and trvias of table tennis
A: Answer
Q: Jurse O'Riordan has to give ceftriaxone to a 5-year old weighing 18 kg. The recommended dose is 100 ...
A: The dosage of Ceftriaxone should be given is 1.8grams.
Q: Why does amplitude decrease in a train of action potential
A: Nerves transmit impulses to and from the central nervous system. Twelve pairs of cranial nerves conn...
Q: If humans came from apes, why are there still apes?
A: It is a common misnomer that humans have descended from apes, as the actual fact states that humans ...
Q: Today, it is easy to make transgenic plants and animals. What are some important safety and ethical...
A: Recombinant DNA technology Insertion of desired foreign DNA in an organism.
Q: EPITHELIUM.
A: The epithelium is a type of body tissue that forms the covering on all internal and external sur...
Q: Which of the following sequences correctly describes the overall process of metabolizing glucose? O ...
A: Step by step description of the four stages of Metabolizing Glucose. 1. Glycolysis:- In glycolysis,...
Q: Who's is the father of cell biology? And give a little history about him
A: Cell is present in all organism and is a chief elemental unit of the body which is site for various ...
Q: A reaction in an anabolic pathway is found to have a large negative Gibbs Free energy. How likely is...
A: Gibbs free energy is basically defined as the amount of work done in the thermodynamic process when ...
Q: Activity 1.3: Complete the table. Directions: Explain and give application for each process/tools. P...
A: 1.Restriction enzyme Explanation- A restriction enzyme is a protein that recognises a specific, sho...
Q: Define interlobular duct
A: The digestive system is responsible for food digestion, absorption, and assimilation along the alime...
Q: What are 5 facts about fermentation?
A: Introduction: Pyruvic acid is a 3 carbon compound formed as the end product of glycolysis. Glycolys...
Q: What is the Solubility Properties of Annatto Seeds?
A: Annatto seeds are derived from Bixa orellano tree,native to tropical regions.Annatto seeds are used ...
Q: nswer is anaerobic respiration similar to glycolysis. Provide three reasons to justify your answer. ...
A: The process by which organisms combine oxygen with foodstuff molecules and produced the chemical en...
Q: 5. 10
A: Taxonomic Key -- A key is a device , which when properly constructed and used enables to identify a...
Q: Which group is the least related to humans? Name two organisms that don't form a clade together. Exp...
A: The phylogenetic tree is called an evolutionary tree. The tree represents the evolutionary relations...
Q: Which statement is false. Glycolysis reduces two molecules of NAD+ into NADH. Glycolysis breaks down...
A: Introduction: The process by which the glucose (6C compound) is split into two molecules of pyruvic ...
Q: Compare and contrast prokaryotic cells with eukaryotic cells. Please write a comparison sentence tha...
A: A cell is the basic unit of life. All living creatures are made up of cells. Cells are the fundament...
Q: Both Porifera and Placozoa possess epithelial tissues. True False
A: ''Since you have asked multiple question, we will solve the first question for you. If you want any ...
Q: 1. Identify the organ.
A: This organ starts from cricoid cartilage and finishes near the heart, where it splits into two parts...
Q: the chemostat.
A: Chemostats in research are used for investigations in cell biology, which is a source for large volu...
Q: Šize-dependent migration distances of DNA fragments in an agarose gel Length of DNA fragments (bp) D...
A: *NOTE: Kindly repost for other questions. Dear Student as per the guidelines we are supposed to answ...
Q: Suggest five experimental research titles that is can be easily done(perform), interesting, will ben...
A: The top models of orientation in the visual cortex The improvement of brain activity Robotic techno...
Q: Let's work on Z and D values. In the graph below, what are the z-values for each of the curves shown...
A: Linear (XY) graph has points that show the relationship between two sets of data. A XY Line graph us...
Q: rtant to have a isolated colony? Please use your own words when answering, simple and to the point :...
A: A group of bacteria, fungi, and other microorganisms grown on a solid agar medium represent a colony...
Q: Please match the tissue to the description. covers the ends of bones in a joint [ Choose ] [Choose ]...
A: Covers the end of bone - cartilage Moves food through intestine - smooth muscles. Lines the lumen of...
Q: recommendations or essay for my ecological footprint
A: Ecological Footprint The Ecological Footprint is a resource accounting tool that measures how much b...
Q: Discuss the structure and functions of a cell membrane comprehensively
A: Introduction "A cell is the smallest, most fundamental unit of life, responsible for all of life's o...
Q: what are some tips to improve image quality when looking at a organsims using a microscope
A: ANSWER;- Some tips to improve image quality example;- Little things like the cover glass thickness, ...
Q: Two proteins are discovered, and both are shown to have a potential in treating fatty liver disease...
A: There are few points fatty liver syndrome . These are as follows : We know that fatty liver syndrom...
Q: t does it mean to say that sponges are monoecious?
A:
Q: 1. IDENTIFY THE LINING. 2. IDENTIFY THE ORGAN. 3. IDENTIFY THE SPECIAL STRUCTURE.
A: This diagram is of the mucus layer, which we can clearly identify as we can see in the image 3 layer...
Q: Pollution is irresponsible action How did pollution b Directions:
A: Pollution -- Pollution is not a new phenomenon and is the greatest problem facing humanity and leadi...
Q: Complete the energy pyramid by writing the source of the energy for the food web and how much energy...
A: Introduction An organism's trophic level is the position it holds in a food chain. A food chain is a...
Q: ou have a farm with calves having issues with scours at 7-10 days of age. You want to esign a vaccin...
A: A.. An intestinal scour vaccine and injectable scour vaccine. B.. Calves are most at risk of calf sc...
Q: Low-resolution X-ray diffraction analysis of a protein composed of long stretches of the sequence (-...
A: The X-ray diffraction is one of the analytical techniques in which the X-rays are used for analysis ...
Q: Why do we need to assess the potential hazards in your community?
A: The term community is associated with the gathering of living organisms that can be found in a parti...
Q: a. What was different about the two protein solutions? b. How does the Biuret indicator detect prote...
A: Detection of proteins Biuret reaction Biuret reagent is used in the reaction of detecting proteins ...
Q: This is compact bone, please use ARROWS to identify the following: osteon lamella lacuna canaliculi...
A:
Q: Describe how fertilizers affect disease severity. Give three examples of fertilizer practices that i...
A: Fertilizers can be described as the chemical substances that are administered to plants in order to ...
Q: Picture A Frog Muscle 3 6. 1 1 4 A 5.
A: Ventral refers to front part of the body (anterior) Ex: stomach is ventral Dorsal refers to back por...
Given that the transgene used is only upregulated in the brain and spinal cord of TMFN mice, what might account for the TMFN mice having less severe cardiac dysfunction in response to LPS challenge?
Step by step
Solved in 2 steps
- The mouse thymus normally contains about 1–2 ´ 108 thymocytes, the vast majority of which are CD4+CD8+ (double-positive) cells. When thymocytes from mice with a gene deficiency in the TCRa locus are compared with those from TCRb-deficient mice, a striking difference between the two different knockout lines is observed, as shown in the figure below in a simplified version of flow cytometry data. The numbers of thymocytes in each thymus is indicated below the plots. What is the explanation for the difference in thymocyte subsets and cell numbers observed when comparing TCRa-/- to TCRb-/- thymocytes? Which region of the thymus organ would show a dearth of developing thymocytes in the TCRa-/- thymus? Which region in the TCRb-/- thymus?What elements are involved in IPTG Induction?please help me I can't find answers for these questions: here is the link for the article https://www.pbs.org/wgbh/nova/transcripts/2805cancer.html What type of substances are angiostatin and endostatin and where are they produced? What do they do? A) describe the experiments using cow bones to discover anti-angiogenic substances. Why was this used as a source of these potential proteins? B) describe the “accidental” discovery of a novel antiangiogenic substance because of lab contamination?
- Technically explain the hybridoma technology that enables monoclonal anchor production.Alefacept is a fusion protein that contains the CD2-binding domain of LFA3 fused to human IgG1, and it is used to block CD2 function on human T cells. In addition, following in vivo administration, alefacept was also shown to deplete T cells of the effector or memory subsets that express high levels of CD2. Surprisingly, clinical trials data indicated that patients on alefacept still retained responses to vaccination. For example, one set of data showed that patients on alefacept made similar responses as the control group to a vaccine designed to protect against pneumococcal disease, which is composed entirely of bacterial polysaccharide antigens (pneumococcal polysaccharide vaccine; PPV). This normal response to PPV by patients on alefacept is not surprising because: Alefacept is not very effective at blocking T cell responses. CD2 is not required for all T cell responses to vaccination. Alefacept does not deplete all effector or memory T cells, just a subset. T cells are involved…A snapshot of a portion of the SARS-CoV-2 spike protein bound to the human ACE2 receptor (taken from PDB) is shown below. The spike protein is in orange and the ACE2 receptor is in green. Within the red-circled region are 2 amino acids connected by a dashed line (added by Dr. David). These amino acids are a tyrosine residue from the spike protein and an aspartate residue from the ACE2 receptor. w cozed
- 1) Briefly outline the location, isolation , characterisation, benefits, and limitations of adult stem cells in TERM 2) Describe and compare the various potencies exhibited by stem cell pheno type 3) Outline the in vitro/in vivo mechanical forces that can be used to influence the quality of cell response and tissue formation obtained by TE..What is Stem cell therapy for Covid-19? and What could be its possibilities and challenges?Variable addition and subtraction of nucleotides at the junctions between gene segments contributes to the diversity of [Qi] the third hypervariable region. The addition and subtraction of nucleotides at the junctions between V, D, and J gene segments creates antibody proteins with wide variations in the numbers of amino acids in their CDR3 regions. This variability in CDR3 length is important as: Overall variability in CDR3 sequence is needed to create a sufficiently diverse antibody repertoire. The CDR3 region is more important in binding antigen than the CDR1 and CDR2 regions are. Some light chains bind better to heavy chains with longer CDR3 region sequences. Longer CDR3 sequences generally create antibodies with higher affinity for the antigen. Some antibodies bind relatively flat surfaces and others bind deep clefts in the antigen.
- Link: Lack of RAC1 in macrophages protects against atherosclerosis - PMC (nih.gov) Could somone explain exactly what this means below? NOT HW just trying to get a better understanding on what this experiment is about. To produce mice that are deficient for RAC1 in macrophages, female C57BL/6 mice homozygously expressing the floxed Rac1 gene (Rac1fl/fl) [6] were crossbred with male mice homozygously expressing Cre under the monocyte-specific lysozyme M promoter (LC) [12]. Mice were genotyped for Rac1 deficiency as previously describedHow do loss of function mutations associated with Artemis (protein) cause their resulting phenotypes? Explain how genetically modified HSCs can treat these phenotypes.Synaptic vesicles release into the synapse to give the message to the post synaptic neuron?Multicellular organisms:a) are larger in size than unicellular organisms b) can do a wider variety of functionsFor a stroke patient with hypertension who is a candidate for recombinant tissue plasminogen activator rt pa which blood pressure control strategy is appropriate?