In the citric acid cycle, isocitrate is oxidatively decarboxylated by theenzyme isocitrate dehydrogenase to yield?a. Alpha-ketoglutarate, CO2 and NAD+O b. Alpha-ketoglutarate, CO2 and GTPO c. Alpha-ketoglutarate and CO2O d. Alpha-ketoglutarate, CO2 and NADH

The citric acid cycle – also known as the TCA cycle (tricarboxylic acid cycle) or the Krebs cycle…

Answered: In the citric acid cycle, isocitrate is…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Which of the following is the second step of Citric Acid Cycle? Select one: a. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH b. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH c. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH d. Malate is oxidized to become oxaloacetate forming NADH e. Fumarate is combined with water to become Malate f. Citrate is rearranged to become Isocitrate g. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide h. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) i. Succinate is oxidized to become fumarate forming FADH2
Which of the following is the sixth step of Citric Acid Cycle? Select one: a. Succinate is oxidized to become fumarate forming FADH2 b. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH c. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH d. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) e. Malate is oxidized to become oxaloacetate forming NADH f. Fumarate is combined with water to become Malate g. Citrate is rearranged to become Isocitrate h. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide i. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH
identify the reactions of the citric acid cycle that provide reducing power for the electron-transport chain a. conversion of succinyl-CoA to succinate b. conversion of fumarate to malate c. conversion of succinate to fumarate d. conversion of malate to oxaloacetate
How many ATPs would result from the reaction involving the alpha-ketoacid dehydrogenase complex alone if one mole of glucose was oxidized in the citric acid cycle? A. 10 B. 5.0 C. 2.5 D. 1.0 E. 0.5
The citric acid cycle is a series of 8 reactions that oxidizes the acetyl group of acetyl CoA to 2 molecules of CO2. The citric acid cycle needs охудen because? a. Oxygen is required to generate NADH and FADH2 O b. Oxygen is required to accept electrons from NADH and FADH2 in oxidative phosphorylation Oxygen is required to donate electrons when NAD+ and FAD are regenerated
Which of the following is the third step of Citric Acid Cycle? Select one: a. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH b. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide c. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH d. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH e. Succinate is oxidized to become fumarate forming FADH2 f. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) g. Citrate is rearranged to become Isocitrate h. Malate is oxidized to become oxaloacetate forming NADH i. Fumarate is combined with water to become Malate
The consumption of acetyl-CoA by the citric acid cycle is DECREASED under which condition? A. the concentration of NAD+ being high B. the concentration of oxaloacetate being high C. NADH being rapidly re-oxidized via the electron-transport chain D. the mitochondrial ATP synthase being inactive E. the concentration of both NAD+ and oxaloacetate being high
The reaction catalyzed by glyceraldehyde 3-phosphate dehydrogenase involves two "sub-reactions", one of which is unfavourable. How is the energy barrier of this unfavourable sub reaction overcome? A. through the formation and hydrolysis of a thioester bond using a cysteine molecule in the enzyme B. through the hydrolysis of an ATP molecule C. through the hydrolysis of a thioester bond in the substrate molecule D. the enzyme catalyzes the formation of a thioester bond E. none of these explanations describe how the energy barrier is overcome Please answer asap
Which of these is not true of the citric acid cycle?a. The citric acid cycle includes the prep reaction.b. The citric acid cycle produces ATP by substrate-level ATPsynthesis.c. The citric acid cycle occurs in the mitochondria.d. The citric acid cycle produces two ATP per glucose molecule.
Match the description with the correct enzyme : A. Glucose 6-phosphate dehydrogenase Serves a as a direct link between citric acid cycle and electron transport chain B. Succinate dehydrogenase v Uses alpha-keto carboxylic acid as a substrate C. Alcohol dehydrogenase Does not contribute electron carriers to oxidative phosphorylation D. NADH dehydrogenase E. Isocitrate dehydrogenase F. Pyruvate dehydrogenase complex
Which of the following dehydrogenases delivers electrons to directly to UQ in the electron transport pathway from the intermembrane space side of the inner mitochondrial membrane? a. succinate dehydrogenase b. acyl CoA dehydrogenase c. creatine kinase dehydrogenase d. glycerol-3-phosphate dehydrogenase
Which of the following citric acid cycle intermediates is decarboxylated during the operation of the cycle? A. More than one correct response B. No correct response C. Isocitrate D. Succinate E. Oxaloacetate

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In the citric acid cycle, isocitrate is oxidatively decarboxylated by the enzyme isocitrate dehydrogenase to yield? O a. Alpha-ketoglutarate, CO2 and NAD+ O b. Alpha-ketoglutarate, CO2 and GTP O c. Alpha-ketoglutarate and CO2 O d. Alpha-ketoglutarate, CO2 and NADH