Match the following proteins to their functions ✓ Cathepsins ✓ Calpains ✓ Granzyme B ✓ Apoptosis inducing factor ✓ Apaf-1 • Bax - A. Cleaves iCAD, leading to DNA fragmentation B. A component of the apoptosome that results in the activation of pro-caspase 9 C. Activation of caspase 12 in response to increased intracellular Ca2+ D. Homodimers form pores in the outer membrane of the mitochondria E. A mitochondrial flavoprotein that induces chromatin condensation and DNA fragmentation F. Mitochondrial permeability, externalization of phosphatidylserine on the plasma membrane of apoptotic cells

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
Problem 19P: Figure 28.11 depicts the eukaryotic cell cycle. Many cell types “exit� the cell cycle and...
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Match the following proteins to their functions
✓ Cathepsins
✓ Calpains
✓ Granzyme B
✓ Apoptosis inducing factor
✓ Apaf-1
• Bax
A. Cleaves iCAD, leading to DNA fragmentation
B. A component of the apoptosome that results in the
activation of pro-caspase 9
C. Activation of caspase 12 in response to increased
intracellular Ca2+
D. Homodimers form pores in the outer membrane of the
mitochondria
E. A mitochondrial flavoprotein that induces chromatin
condensation and DNA fragmentation
F. Mitochondrial permeability, externalization of
phosphatidylserine on the plasma membrane of apoptotic
cells
Transcribed Image Text:Match the following proteins to their functions ✓ Cathepsins ✓ Calpains ✓ Granzyme B ✓ Apoptosis inducing factor ✓ Apaf-1 • Bax A. Cleaves iCAD, leading to DNA fragmentation B. A component of the apoptosome that results in the activation of pro-caspase 9 C. Activation of caspase 12 in response to increased intracellular Ca2+ D. Homodimers form pores in the outer membrane of the mitochondria E. A mitochondrial flavoprotein that induces chromatin condensation and DNA fragmentation F. Mitochondrial permeability, externalization of phosphatidylserine on the plasma membrane of apoptotic cells
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