Mendelian Genetics and Non-Mendelian Genetics: Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jillian is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married  Jacobwhose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia. 1. Give the genotypes of Jillian and Jacob.       Assuming that they will have 4 children, what is the probability that: 2. all their children will be normal? 3. they will have a son with Huntington’s disease?  4. they will have a daughter inflicted with both conditions

Human Anatomy & Physiology (11th Edition)
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Mendelian Genetics and Non-Mendelian Genetics: Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jillian is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married  Jacobwhose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia.

1. Give the genotypes of Jillian and Jacob.      

Assuming that they will have 4 children, what is the probability that:

2. all their children will be normal?

3. they will have a son with Huntington’s disease? 

4. they will have a daughter inflicted with both conditions

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