Most normal tissues contain resident macrophages, and connective tissue sites in the gastrointestinal tract and the lung contain large numbers of these cells. Yet the blood also contains a high number of circulating ‘classical’ monocytes that can differentiate into macrophages after entering tissues. These circulating monocytes function to: Phagocytose and kill pathogens in the blood Line the endothelial surfaces of the blood vessels with phagocytic cells Enter lymph nodes and patrol for infecting microbes in these organs Amplify the local innate immune response by entering tissues that are infected Differentiate into dendritic cells during an inflammatory response
Most normal tissues contain resident macrophages, and connective tissue sites in the gastrointestinal tract and the lung contain large numbers of these cells. Yet the blood also contains a high number of circulating ‘classical’ monocytes that can differentiate into macrophages after entering tissues. These circulating monocytes function to: Phagocytose and kill pathogens in the blood Line the endothelial surfaces of the blood vessels with phagocytic cells Enter lymph nodes and patrol for infecting microbes in these organs Amplify the local innate immune response by entering tissues that are infected Differentiate into dendritic cells during an inflammatory response
Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Chapter37: Immunity
Section: Chapter Questions
Problem 10SQ: Cell-mediated responses are most effective against ______. a. intracellular pathogens b....
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Q1. Assessment .
Most normal tissues contain resident macrophages, and connective tissue sites in the gastrointestinal tract and the lung contain large numbers of these cells. Yet the blood also contains a high number of circulating ‘classical’ monocytes that can differentiate into macrophages after entering tissues. These circulating monocytes function to:
- Phagocytose and kill pathogens in the blood
- Line the endothelial surfaces of the blood vessels with phagocytic cells
- Enter lymph nodes and patrol for infecting microbes in these organs
- Amplify the local innate immune response by entering tissues that are infected
- Differentiate into dendritic cells during an inflammatory response.
Chose.
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