OH 16,17-dehydroprogesterone

Q: From what you have learned about enols and the hydration of alkynes, predict what product is formed…

A:

Q: Consider the following synthetic sequence: он A Cro/H* F CH;Br CH,MgBr E в Br2.FeBr3 G C3H,Bro…

A: In the given reaction sequence alkyl halide first converts into Grignard reagent which reacts with…

Q: 1. The molecular formula of an unknown compound A is C7H14. On ozonolysis, A gave two products B…

A: The given compound (A) has molecular formula C7H14 which suggest that A is an alkene as alkenes have…

Q: Many variations of ring-closing metathesis have now been reported.Tandem ring–opening–ring-closing…

A: In a Diels-Alder reaction a diene reacts with a dienophile to produce cycloalene derivative

Q: Heating an alcohol with sulfuric acid is a good way to prepare a symmetrical ether such as diethyl…

A: a) Since in case of reacting an alcohol with sulfuric acid, the formed carbocation can be attacked…

Q: Sulfur ylides, like the phosphorus ylides of Chapter 21, are useful intermediates in organic…

A: The ion containing -ve charge over C-atom as well as a +ve charge over the heteroatom (S, N and P)…

Q: In the following scheme, establish who is A and B to obtain 2-tert-butyl-1-methyl-pyrrole C, write…

A: Reaction goes via friedel craft alkylation reaction.

Q: Why is it not advisable to use aqueous hydrochloric acid in a Grignard reaction of a ketone? A) The…

A: Alkyl magnesium halide is known as a Grignard reagent. The general formula of the Grignard reagent…

Q: Define the Reaction of Organometallic Reagents with Other Compounds ?

A: The compounds containing bond between carbon and a metal are termed as organometallic compound.

Q: What are the hazards associated with: a) sodium methoxide and b) methanol? Draw the step by step…

A:

Q: :Explain the following Diazotization reaction carried out during the preparation of p-iodotoluene…

A: Diazotization reactions:

Q: Brevicomin, the aggregation pheromone of the western pine bark beetle, contains a bicyclic bridged…

A:

Q: Devise a stepwise synthesis of attached compound from dicyclopentadieneusing a Diels–Alder reaction…

A: A stepwise synthesis of attached compound from dicyclopentadiene has to be devised.

Q: Hydroxy aldehydes A and B readily cyclize to form hemiacetals. Draw the stereoisomers formed in this…

A: The formation of a cyclic hemiacetal is an acid catalyzed reaction. The cyclic hemiacetals formed by…

Q: The analgesic acetaminophen is synthesized by treating 4-aminophenol with one equivalent of acetic…

A: Given 4-aminophenol + acetic anhydride ----> acetaminophen + additional product

Q: HO, ОН

A:

Q: Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works by inhibiting…

A:

Q: 14. Explain why pyrrole is an electron-rich heterocycle that is activated toward electrophilic…

A: In case of pyrrole, the l.p. present on N atom is heavily delocalized into the ring to maintain…

Q: n synthesis of benzoic acid with Grignard reagent, benzene is often detected as an impurity. How is…

A: Grignard Reagent  Are very Powerful  base which Takes Place H+  From solution  and get converted…

Q: Treatment of ketone A with LDA followed by CH3CH2I did not form the desired alkylation product B.…

A: The product formed in the reaction is shown below.

Q: 66. ALL of the following Ether can be prepared by Williamson's method, EXCEPT: A. Ditertbutyl ether…

A: Option (a)  In order to prepare di-tert- butyl ether, sodium tert-butoxide must be reacted with tert…

Q: Treatment of α,β-unsaturated carbonyl compound X with base forms the diastereomer Y. Write a…

A: In the reaction, racemization of a methyl group linked to gamma -carbon atom takes place. For…

Q: What product is formed by ring-closing metathesis of compound V, a key intermediate in the synthesis…

A: The ring-closing metathesis (RCM) by Grubbs catalyst occurs, when the starting material is diene.…

Q: Draw a stepwise mechanism for the conversion of lactone A to ester B using HCl in ethanol. B is…

A: In the first step of the mechanism the carbonyl group undergoes protonation followed by attack of…

Q: How to determine the relative basicity of nitrogen heterocycles ?

A: Heterocyclic compounds are aromatic hydrocarbons with one or two hetero atoms like O or N. Some well…

Q: What starting materials are needed to prepare ar-turmerone using a directedaldol reaction?…

A: A species with a larger size can easily accommodate negative charge. In other words, in a large size…

Q: What epoxide and organometallic reagent are needed to synthesize attachedalcohol?

A:

Q: What product is formed when each compound undergoes anintramolecular reaction in the presence of…

A: The formation of a cyclic hemiacetal is an acid catalyzed reaction. The cyclic hemiacetals formed by…

Q: Synthetize 3-pentynal from 3-butynal using whatever organic/inorganic reagents are needed.

A: Organic reaction mechanisms:

Q: Although 2-methyl-1,2-propanediol is an unsymmetrical vicinal diol, only one product is obtained…

A: vicinal diol is a compound with two -OH groups on adjacent carbons.…

Q: a) Wolff-Kishner reduction of compound W gave compound A. Treatment of A with m- chloroperbenzoic…

A: Oxidation and reduction are common class type of organic reactions. In oxidation reaction, oxygen is…

Q: Devise efficient laboratory syntheses of ethers and epoxides, including the following:(a) The…

A:

Q: Ozonolysis of compound A, C,H12 gave two products B and C. Further analysis of these two compounds…

A:

Q: The last step in the synthesis of divinyl ether (used as an anesthetic under the name Vinethene)…

A:

Q: The following product was obtained from the ozonolysis of an alkene followed by treatment with…

A: Ozonolysis of alkene is the reaction of alkene with ozone forms ozonide this on further hydrolysis…

Q: Please provide the conditions (A) to prepare reagent (B) for the following transformation. A 1. PPH3…

A: - carbonyl reacts with the wittig reagent to give alkene as a major product  - alkyl halide reacts…

Q: Which of the following requires a tert-butanol as one of the reactants in Williamson ether…

A:

Q: Besides the tert-butyldimethylsilyl ethers, there are many other widely used alcohol protecting…

A: a. A stepwise mechanism for the formation of MOM ether from cyclohexanol is shown below:

Q: (a) 1-methylcyclopentene B can be prepared by an intramolecular Wittig reaction from A. Propose a…

A:

Q: a. Would you expect hemiacetals to be stable in basic solutions? Explain your answer.b. Acetal…

A: a. Hemiacetals are easily converted to carbonyl compounds in basic medium. Base removes alcoholic…

Q: Draw the first intermediates after the pericyclic decarboxylation of 3-oxobutanoic acid with heat.

A: In this question, we will draw first intermidiate after pericyclic decarboxylation.  You can see…

Q: The Stork reaction is a condensation reaction between an enamine donor and an α,β-unsaturated…

A: The structure of enamine formed is drawn as,

Q: From what you have learned about enols and the hydration of alkynes, predict what product is formed…

A: Note: In the question, double bond is shown instead of triple bond. Alkyne has triple bond

Q: Brevicomin, the aggregation pheromone of the western pine bark beetle, contains a bicyclic bridged…

A:

Q: The biosynthesis of lanosterol from squalene has intrigued chemists since its discovery. It is now…

A: a. The first step is the protonation of hydroxyl group. In the next step, elimination of water…

Q: Synthesize pyrrolidin-2-yl-methanol from pyrrole. For this you need 4 reactions (A, B, C and D).…

A: The three important steps for this synthesis of desired compound involves insertion of CHO group at…

Q: 1. Explain the solubility behavior of the alcohols and phenols in water as a function of: a.…

A: (1) It is observed that Alcohols are more soluble in water due to formation of Hydrogen bonding…

Q: 4-Methylpyridine reacts with benzaldehyde (C6H5CHO) in the presence of base to form A. (a) Draw a…

A: a) A stepwise mechanism of the given reaction is,

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.