People who carry a theoretical genetic disorder (called B-disease) can be identified from a 2kb DNA sequence. People who carry this genetic disorder have a single nucleotide polymorphism that results in a change of GTATCC to GGATCC, a site that only occurs once at nucleotide number 750 in this DNA sequence. Answer the following questions based on the information provided. (a) How can you develop a simple molecular test to identify the genetic disorder?r B-dif w. (41 (b) If you have carried out the molecular test (based on the information above) on a 100 individual and found that 24 were healthy (BB) and 26 were carriers (bb); 1) What is the ratio of heterozygous? 2) Show how can you identify the three types from the agarose gel (H focai

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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People who carry a theoretical genetic disorder (called B-disease) can be identified from
a 2kb DNA sequence. People who carry this genetic disorder have a single nucleotide
polymorphism that results in a change of GTATCC to GGATCC, a site that only occurs
once at nucleotide number 750 in this DNA sequence. Answer the following questions
based on the information provided.
(a) How can you develop a simple molecular test to identify the genetic disorder?r B-dif
w. (41
(b) If you have carried out the molecular test (based on the information above) on a 100
individual and found that 24 were healthy (BB) and 26 were carriers (bb); 1) What is the
ratio of heterozygous? 2) Show how can you identify the three types from the agarose
gel (H focai
Transcribed Image Text:People who carry a theoretical genetic disorder (called B-disease) can be identified from a 2kb DNA sequence. People who carry this genetic disorder have a single nucleotide polymorphism that results in a change of GTATCC to GGATCC, a site that only occurs once at nucleotide number 750 in this DNA sequence. Answer the following questions based on the information provided. (a) How can you develop a simple molecular test to identify the genetic disorder?r B-dif w. (41 (b) If you have carried out the molecular test (based on the information above) on a 100 individual and found that 24 were healthy (BB) and 26 were carriers (bb); 1) What is the ratio of heterozygous? 2) Show how can you identify the three types from the agarose gel (H focai
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