Problem 2. Propose reaction mechanism. NM²3 r 10 eq 130°C, N₂ Na₂S₂ 13 eq H₂O 78%

The following figure shows the energy profile of a nucleophilic substitution reaction. Potential energy :ÖH H HII.C H C-1 H HO--C---I HH Reaction coordinate H -CH HO–CHITH H + 1 According to this, it is correct to affirm: O The activation energy (4G°) shows that it is thermodynamically favorable. O Represents a reaction that occurs in one step where a pentavalent chemical species is formed. O The intermediate has lower energy than any transition state. O The formation of the intermediate releases energy and is therefore thermodynamically favourable.

Mechanism: A reaction mechanism for the following reaction is shown below. H+ CEN CEN: N-H || -C-OH H₂O, H* Step 1 wand woled mot ozsm E Step 3 N-H C-OH C=N-H Step2 C=N-H H-O-H H₂O motno vgiene fesrigid onlt to smotnos -C=N-H a) The overall reaction is an example of b) Step 1 is c) Step 3 is d) Draw in the curved arrows for each step. e) Identify the nucleophiles and electrophiles where appropriate. f) Fill in the reaction energy diagram. H₂O: rate determining step to noipojovo hamwell sit 5(emise erit voittons 10) vanas mi sdgin al rainW di of E^ reaction progress →

Propose a plausible mechanism for the followng reaction INa, NH3 (liq) 2 NH CI

Which mechanism describes best the reaction below? LARV 2021 DS H,0 A H-ỎH, HO B H-ÓH, CH Under described conditions, this reaction is not possible O B OD O A étv DD F12 F1 令

owing reactions proceeds via an SN1 or SN2 of the reaction: (b) S2 pro85 39 Br tort atubong auonsV HMPAnoitutitadua

4. Outline a detailed mechanism for the reaction below. Identify the abbreviation for the reaction mechanism. НО H3PO4

What is the major organic product of the following reaction? Problem viewing the image, Click Here O A OB O C OD A. B. C. C. D. 1. Hg(OAc)2, H₂O 2. NaBH4 D. OH t to allo OH OH f OH (+) OH (+) (±)

67- g/ Give a reaction mechanism OH EtO,CN=NCO,Et 'NO2 CH,NO2 PPH3 92%

Predict the product for the following reaction. ✔Saved CI || |||| IV NaCN CN ∞∞ m 111 CN CN IV CN