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- Please, I need help. 1. YOU ARE WORKING WITH A NEW DRUG TO TREAT BREAST TUMORS. PRESENT AN OUTLINE OF THE STEPS YOU WOULD CARRY OLUT IN PRECLINICAL TESTING. WHAT ASPECTS OF DRUG ACTIVITY AGAINST THE TUMOR CAN BE ADDRESSED: IN MONOLAYER CULTURE? IN MUTICELLULAR TUMOR SPHEROID CULTURE? WHAT TYPES OF COMPLEX TISSUE CULTURE ENVIRONMENTS MAY ALSO BE USEFUL FOR DRUG TESTING?Please answer the following queations about cancer 1. Correct mechanism in cancer disease 2. Faulty mechanism in cancer disease 3. Graphic of pathway in cancer disease. 4. Describe a "real life" example of how cancer disease has affected someone (try to find an axample of famous person or anyone).Can you critically evaluate this information including details in the discussion, also including molecular and cellular aspects as well as detailed diagnostic and treatment approach:- When tumours attempt to spread/invasive outside of their original tissue or to a remote metastatic location, they are said to be invasive. This process is typically started or sustained by the microenvironment around the tumour. Examine in-depth/Critically what a cancer microenvironment is and how it's considered to encourage tumour migration.
- You are evaluating a 55 year old breast cancer patient who has been on Raloxifene and Pertuzumab for the past year, which of these features do you think is least indicative of tumor resistance? Group of answer choices Tumor regression and remission after therapy Relapse after remission Increasing tumor size Metastatic lesion in the sternumTRUE OR FALSE 1. Atrophy is better observed or identified in a macroscopic examination of a tissue, organ or any part of the body 2. Metaplasia is the cellular adaptation most associated with cancer.Match the letter of the drug/treatment with the appropriate answer Cell cycle inhibitor directed against breast cancer / Choose. T-vec Gene therapy product approved in China to replace p53 Provenge IBRANCE Oncolytic virus therapy that lyses cancer cells and elicits an immune response Gendocine Oncorine Gardisal Oncolytic virus therapy used for p53-deficient tumors Choose... Choose... Prophylactic vaccine used to prevent cervical cancer Choose... Therapeutic vaccine directed against prostate cancer
- Tell the Story” of a specific cancer pathology of your choosing, Your post should: Focus on the risk, diagnosis, types, stages, treatments, and results shown by statistics Include a helpful reference video (curated, not created by you) to strengthen your post Provide a robust discussion submission including all of the elements listed aboveDiscuss why cancer treatment may involve a combinationof chemotherapy, radiation therapy, and surgery.Answer and explain your choice to the following multiple-choice questions about cancer-promoting mutations. The ABC gene undergoes multiple gene duplication events, producing multiple copies of this gene in the genome. This gene duplication event is associated with cancer. What would best describe the normal function of ABC gene? Inhibit cell growth and division Oncogene Inhibit apoptosis Metabolic enzyme EXPLAIN in 1-2 sentences: A mutation in the epidermal growth factor receptor (EGFR) causes it to send a positive signal along its intracellular signaling pathway, even without the EGF ligand bound to it. Knowing the function of a growth factor, how would you classify this mutation? an activating mutation in a tumor suppressor gene an activating mutation in a proto-oncogene a loss of function mutation in a tumor suppressor gene a loss of function mutation in a proto-oncogene EXPLAIN in 1-2 sentences: In an otherwise normal cell, what would be the immediate result of a…
- Discuss the clinical uses of tumor markers in a maximum of 5 sentences.A client had a positive Pap smear. When staging the lesion, the surgeon diagnosed "cancer in situ of the cervix." The client asks, "What does this mean?" From the following statements, which is most appropriate in response to this question? O There is not enough information to determine the stage. O The tumor has undifferentiated cells that no longer look like the tissue from which it arose O Abnormal cells are present only in the layer of cells in which they developed Cancer has spread from the primary site to distant tissues or org or to distant lymph nodesThe following paragraph is taken from the National Cancer Institute’s web site on the PSA test for prostate cancer. The paragraph is the complete discussion of false positive PSA results offered on the web site. • What are some of the limitations of the PSA test? • False-positive tests: False-positive test results (also called false positives) occur when the PSA level is elevated but no cancer is actually present. False positives may lead to additional medical procedures that have potential risks and significant financial costs and can create anxiety for the patient and his family. Most men with an elevated PSA test result turn out not to have cancer; only 25 to 35 percent of men who have a biopsy due to an elevated PSA level actually have prostate cancer. Is the last sentence in the paragraph immediately above about false positives as the paragraph is entitled or is it about the left-hand side of Bayes Theorem? Explain.