Question 18 100 methyt p-ydedestin () methyt ydedestrin () NMO IgG Control IgG In the experiment above, untreated cells (methyl-B-cyclodextrin (-)) or cells treated with methyl-B-cyclodextrin (+) were incubated with anti-sera from either NMO patients or control patients. After 1 h, the number of dead cells were counted and expressed as % cytotoxicity. What did the data show? Methyl B-cyclodextrin did not affect the toxicity of anti-sera from NMO patients In the presence of methyl-B-cyclodextrin, anti-sera from NMO patients was less toxic O In the presence of methyl-B-cyclodextrin, anti-sera from NMO patients was more toxic Question 19 Put all the data together. What might be happening in NMO patients? O Antibodies in NMO patients cause aquaporin to denature into single polypeptide chains Antibodies in NMO patients attack aquaporin clusters that are not in lipid rafts O Antibodies in NMO patients attack aquaporin clusters in lipid rafts Antibodies in NMO patients cause aquaporin to localize to lipid rafts %eytotosicity

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question 18
100
methyl -ydedextrin (-)
methytp-cydodesnin ()
NMO IgG
Control IgG
In the experiment above, untreated cells (methyl-B-cyclodextrin (-) or cells treated with methyl-B-cyclodextrin (+) were
incubated with anti-sera from either NMO patients or control patients. After 1 h, the number of dead cells were
counted and expressed as % cytotoxicity. What did the data show?
O Methyl-B-cyclodextrin did not affect the toxicity of anti-sera from NMO patients
In the presence of methyl-B-cyclodextrin, anti-sera from NMO patients was less toxic
O In the presence of methyl-B-cyclodextrin, anti-sera from NMO patients was more toxic
Question 19
Put all the data together. What might be happening in NMO patients?
Antibodies in NMO patients cause aquaporin to denature into single polypeptide chains
Antibodies in NMO patients attack aquaporin clusters that are not in lipid rafts
O Antibodies in NMO patients attack aquaporin clusters in lipid rafts
O Antibodies in NMO patients cause aquaporin to localize to lipid rafts
%eytatoxicity
Transcribed Image Text:Question 18 100 methyl -ydedextrin (-) methytp-cydodesnin () NMO IgG Control IgG In the experiment above, untreated cells (methyl-B-cyclodextrin (-) or cells treated with methyl-B-cyclodextrin (+) were incubated with anti-sera from either NMO patients or control patients. After 1 h, the number of dead cells were counted and expressed as % cytotoxicity. What did the data show? O Methyl-B-cyclodextrin did not affect the toxicity of anti-sera from NMO patients In the presence of methyl-B-cyclodextrin, anti-sera from NMO patients was less toxic O In the presence of methyl-B-cyclodextrin, anti-sera from NMO patients was more toxic Question 19 Put all the data together. What might be happening in NMO patients? Antibodies in NMO patients cause aquaporin to denature into single polypeptide chains Antibodies in NMO patients attack aquaporin clusters that are not in lipid rafts O Antibodies in NMO patients attack aquaporin clusters in lipid rafts O Antibodies in NMO patients cause aquaporin to localize to lipid rafts %eytatoxicity
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