Ribosome-associated chaperones Native proteins Polypeptide emerging from ribosome Stress Spontaneous or chaperone- mediated protein folding: • Hsp70/Dnak • Hsp60/GroEL Hsp90 Untolded, misfolded and non-native proteins Delivery to compartmentalized proteases: • ClpHsp100 Protection from aggregation: *sHsp Hsp70/Dnak • Hsp90 • Clp/Hsp100 Disaggregation" and reactivation: • Cip/Hsp100 + Hsp70 • Hsp90 + Hap70 Degraded proteins Protein aggregates Explain and discuss the diagram. (The Role of Chaperones in Protein Folding) *You can underline or make the keywords bold for emphasis. *You have to base your answers only from our lecture/discussion and not from other sources. Sample structure of essay: 1st paragraph: Introduction and preliminary explanation of the diagram

3-2-1 Code It
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Chapter8: Introduction To Cpt Coding
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Ribosome-associated
chaperones
Native proteins
Polypeptide emerging
from ribosome
3
Stress
Attempts
1 attempt left
Spontaneous or chaperone-
mediated protein folding:
• Hsp70/Dnak
• Hsp60/GroEL
• Hsp90
E Originality Report
SafeAssign enabled
Unfolded, misfolded
and non-native proteins
Grading
Delivery to
compartmentalized
proteases:
• Clp/Hsp100
Protection from aggregation:
• sHsp
• Hsp70/Dnak
• Hsp90
• Clp/Hsp100
E Maximum points
Fool
80 points
Disaggregation
and reactivation:
• Cip/Hsp100 + Hsp70
• Hsp90 + Hsp70
Degraded proteins
Protein aggregates
Explain and discuss the diagram. (The Role of Chaperones in Protein Folding)
*You can underline or make the keywords bold for emphasis.
*You have to base your answers only from our lecture/discussion and not from other sources.
Sample structure of essay:
1st paragraph: Introduction and preliminary explanation of the diagram
2nd paragraph: Follow-up and additional discussion.
3rd paragraph: Final discussion and conclusion.
Pri
O 90 minutes remaining
Save and Close
Submit
Ter
5:42 PM
P Type here to search
28°C
A O O ENG
20/09/2021
近
Transcribed Image Text:A View Assessment Althea Gem messaged you Content A adamson.blackboard.com/ultra/courses/_12158_1/outline/assessment/_1143292_1/overview/attempt/_3601644_1?courseld=_12158_1 Paused Co Exam Content Details & Information Question 1 20 Points Assessment due date 9/20/21, 7:00 PM (UTC+8) X Time limit 90 minutes | Automatic submission Ribosome-associated chaperones Native proteins Polypeptide emerging from ribosome 3 Stress Attempts 1 attempt left Spontaneous or chaperone- mediated protein folding: • Hsp70/Dnak • Hsp60/GroEL • Hsp90 E Originality Report SafeAssign enabled Unfolded, misfolded and non-native proteins Grading Delivery to compartmentalized proteases: • Clp/Hsp100 Protection from aggregation: • sHsp • Hsp70/Dnak • Hsp90 • Clp/Hsp100 E Maximum points Fool 80 points Disaggregation and reactivation: • Cip/Hsp100 + Hsp70 • Hsp90 + Hsp70 Degraded proteins Protein aggregates Explain and discuss the diagram. (The Role of Chaperones in Protein Folding) *You can underline or make the keywords bold for emphasis. *You have to base your answers only from our lecture/discussion and not from other sources. Sample structure of essay: 1st paragraph: Introduction and preliminary explanation of the diagram 2nd paragraph: Follow-up and additional discussion. 3rd paragraph: Final discussion and conclusion. Pri O 90 minutes remaining Save and Close Submit Ter 5:42 PM P Type here to search 28°C A O O ENG 20/09/2021 近
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