ONLY ANSWER 3 Show complete solutions and round off your answers up to 4 decimal places.A prospective study on the relationship between aspirin use and heart attacks by thePhysicians' Health Study Research Group at Harvard Medical School is presented below.The Physicians' Health Study was a 5-year randomized study of whether regular aspirinintake reduces risk of myocardial infarction or heart attack. Every other day, physiciansparticipating in the study took either one aspirin tablet or a placebo. The study was blindthose in the study did not know whether they were taking aspirin or a placebo.Of the 11,034 physicians taking a placebo, 189 suffered heart attacks over the course ofthe study, whereas of the 11,037 taking aspirin, 104 had heart attacks. Can we say that theintake of aspirin appears to diminish the risk of myocardial infarction?Myocardial InfarctionNoGroupTotalYesPlacebo 189Aspirin 104Total 293108451103410933110372177822071Let patients taking placebo be the first group and those taking aspirin in the secondgroup. Calculate the following and make an interpretation:1. risk difference2. relative risk3. odds ratio

Introduction:- Odds ratio is the ratio of odds that the case was exposed to the odds that the…

Answered: Show complete solutions and round off…

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter16: Adult And Pediatric Dosages Based On Body Surface Area

Section: Chapter Questions

Problem 12SST

See similar textbooks

Similar questions

The Physicians' Health Study was a randomized, double-blind, placebo-controlled trial of 22,071 apparently healthy male physicians. Subjects were randomized into two groups: one group took a buffered aspirin every other day and the other was given a placebo. The average follow-up during the aspirin component of the trial was 60.2 months. Baseline cardiovascular risk factors and adherence to therapy during the trial were assessed by questionnaire. Cardiovascular outcomes were reported by questionnaire and confirmed by record review by an Endpoints Committee. Among those taking the aspirin, 104 heart attacks (with five deaths) occurred compared to 189 heart attacks 18 of them fatal among those taking the placebo. The study was terminated early, due principally to a 44% reduction in the risk of a first myocardial infarction (MI). Which of the following are NOT a reason(s) to use a placebo in this trial? Select all that apply. To ensure the ethical review board will approve the…
Read the following scientific paper from J.K Aronson titled: Medication errors: what they are, how they happen, and how to avoid them QJM: An International Journal of Medicine, Volume 102, Issue 8, August 2009, Pages 513– 521, https://doi.org/10.1093/qjmed/hcp052 Focus on the following sections: Abstract One particular medication error Frequency and outcomes of medication errors Conclusion: a prescription for better prescribing Once you have done the reading: Prepare a 150-200 words reflection piece on the importance of Topic 1 measurements for future health care professionals as you. Base your reflection on the resources provided. Drug Dosage and Body mass Medication errors: what they are, how they happen, and how to avoid them) You are most welcome to do quick research on measurement errors in your desired field of practice too (Pharmacy, Paramedic, Nutrition, Health Science, Exercise Science, Physiotherapy etc). To help you out here are some questions to answer in your…
A DVT (deep vein thrombosis) clinic had 320 persons appearing for lower extremities Doppler ultrasound study. If 48 out of 80 subjects with DVT tested positive for the DVT, and 228 out of 240 without DVT tested negative Calculate the following False negative Positive predictive value (PPV) What does this PPV mean Negative predictive value (NPV)
What do you think about the longitudinal NIH-funded Bogalusa Heart Study, created by cardiologist Gerald Bevenson in 1972? This study is following 16,000 who started in childhood and are now adults (40 years thus far). Researchers have looked at several things, on those living, as well as performing autopsies on 560 of these individuals who died since then (of accidental death or otherwise). 20% of autopsied children had plaques (fat deposits) in their coronary arteries, making this the first study of its kind to establish heart disease can exist in children, and those who were obese as children were likely to remain so in adulthood, as opposed to only 7% becoming obese who were not so in childhood.
Azithromycin can be administered either orally as a slow release of active ingredients (known as extended release) or intravenously (IV) into the bloodstream (known as immediate release). Calculate the appropriate dosage of both extended and immediate release azithromycin for a 17.0 lb patient. Orally administered extended-release azithromycin dosage for a child is 60 mg per kg of body weight. Calculate the dosage in mg of azithromycin for a 17.0 lb child. IV administered immediate-release azithromycin dosage for a child is 10 mg per kg of body weight. Calculate the dosage in mg of azithromycin for a 17.0 lb child.
1) Explain the principle of the electrical impedance cell counting. 2) State 3 Haematology analyzer and their manufacturers. 3) CV for automated instrument is +/- 1% to +/- 2% compared to manual count with CV +/- 10%. Can you explain their differences?
A DVT (deep vein thrombosis) clinic had 320 persons appearing for lower extremities Doppler ultrasound study. If 48 out of 80 subjects with DVT tested positive for the DVT, and 228 out of 240 without DVT tested negative Calculate the following Sensitivity Specificity False positive False negative Positive predictive value (PPV) What does this PPV mean Negative predictive value (NPV) What does this NPV here mean The prevalence of DVT What is the 2 x 2 contingency table What is the difference between prevalence with regard to PPV and NPV?
In a placebo-controlled study, 10 healthy subjects were given oral triazolam 0.5 mg before and after rifampicin 600 mg daily for 5 days. Rifampicin reduced the triazolam AUC by 95% and decreased its maximum plasma levels by 88%, when compared with placebo. The elimination half-life was reduced from 2.8 hours to 1.3 hours. Pharmacodynamic tests (drowsiness, sway, Maddox wing, etc.) showed that rifampicin abolished the effects of triazolam.a) Why is the AUC of triazolam reduced in the presence of rifampicin? b) Given the above scenario, if you were to accommodate this situation by dosage adjustment strategies, in the presence rifampicin what dose of triazolam would you have recommended, keeping dosage interval the same as when there was no rifampicin? answer part b
Determine the cause-effect relationship of the following variables given. Choose the best answer that describes the possible changes in the variable (Y) because of the changes done to the variable (X). Faster elimination of tryptophan in the body (x) vs. gout formation (y) Group of answer choices No effect Decrease Increase Cannot be determined
Give detailed Solution with explanation needed of all options..don't give Handwritten answer..don't use Ai for answering this
Obviously, all four patients need to be met with. Based on the graphs above, which two patients have broken the most rules? Explain your answer.
write a summary :Currently used animal and cellular models for pulmonary arterial hypertension (PAH) only partially recapitulate its pathophysiology in humans and are thus inadequate in reproducing the hallmarks of the disease, inconsistent in portraying the sex-disparity, and unyielding to combinatorial study designs. Here we sought to deploy the ingenuity of microengineering in developing and validating a tissue chip model for human PAH. We designed and fabricated a microfluidic device to emulate the luminal, intimal, medial, adventitial, and perivascular layers of a pulmonary artery. By growing three types of pulmonary arterial cells (PACs)-endothelial, smooth muscle, and adventitial cells, we recreated the PAH pathophysiology on the device. Diseased (PAH) PACs, when grown on the chips, moved of out their designated layers and created phenomena similar to the major pathologies of human PAH: intimal thickening, muscularization, and arterial remodeling and show an endothelial to…

SEE MORE QUESTIONS

Recommended textbooks for you

Curren'S Math For Meds: Dosages & Sol

Nursing

ISBN:

9781305143531

Author:

CURREN

Publisher:

Cengage

Curren'S Math For Meds: Dosages & Sol

Nursing

ISBN:

9781305143531

Author:

CURREN

Publisher:

Cengage

SEE MORE TEXTBOOKS