Solute A has a partition coefficient of 4 between diethyl ether and water. If 100 mL of 0.1 M aqueous solution of A is extracted twice with 100 mL of diethyl ether, what is the resulting concentration of A in aqueous layer? (Please show the solution of the correct answer) A. 2.0x10^-3 M B. 4.0x10^-3 M C. 2.0x10^-2 M D. 2.0x10^-2 M

Solute A has a partition coefficient of 4 between diethyl ether and water. If 100 mL of 0.1 M aqueous solution of A is extracted twice with 100 mL of diethyl ether, what is the resulting concentration of A in aqueous layer? (Please show the solution of the correct answer) A. 2.0x10^-3 M B. 4.0x10^-3 M C. 2.0x10^-2 M D. 2.0x10^-2 M

Principles of Instrumental Analysis

7th Edition

ISBN:9781305577213

Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Chapter28: High-performance Liquid Chromatography

Section: Chapter Questions

Problem 28.3QAP

See similar textbooks

Similar questions

A. Water and chloroform has a partition coefficient of 5.00. A 50.00mL sample of a 8M aqueous solution of the solute is extracted with 10.00mL of chloroform. 1. What is the extraction efficiency for this separation? 2. What is the solute's final concentration in each phase? 3. What is the volume of chloroform needed to extract 99.00% of the solute? B. As described in Expt 2.A. determine 1. the extraction efficiency for 3 extractions and 2. the number of extractions required to ensure that 95.00% of the solute is extracted.
A 36.0 mg sample of an organic compound (molar mass = 84.0 g/mol) is dissolved in 10.0 mL of water. This aqueous solution is extracted with 5.0 mL of hexane. Separation and analysis of the aqueous phase shows that it now contains 12.0 mg of the organic compound. Calculate the partition coefficient for the compound between hexane and water (Kphexane/water). Your answer should reflect the proper number of significant figures.
6. ( If the solubility of solute Z is 1.0 g/60 mL in diethyl ether and is 1.0 g/1110 mL in water. a) Determine the partition coefficient for the solute Z in these two solvents. b) If 60 mg of the solute Z were dissolved in 100 mL of water, how much ether would be required to extract 90% of solute Z in a single extraction. c) What percent of the A would be extracted from the aqueous solution in (b) by two 50 mL portions of ether?
A solution of 3g organic compound X in 200ml of water was extracted with 200 ml of ethyl ether. At equilibrium the concentration of Xin the two phases was ; 2.6g/100ml of ethyl ether ; 0.8g/100 ml of water. Calculate the partition coefficient, Kd, for compound X in the system. Show your calculations and What percentage of the original sample of X was extracted? Show your calculations.
The absorbance of a 0.5 mM aqueous salicylic acid solution was 0.925. This solution was extracted with 10% ethyl acetate/hexane solution. The absorbance of the extracted aqueous salicylic acid solution at equilibrium was 0.670. a. Find the equilibrium concentrations of SA in the aqueous and the non-aqueous phases. b. Calculate the partition coefficient (K) for the salicylic acid.
The partition coefficient of caffeine between dichloromethane and water is 4.6. Given a 50 mL saturated solution of caffeine, determine the percent recovery of caffeine in a single extraction using 20 mL of DCM; and determine the percent recovery of caffeine when the extraction is done twice using two portions of 10 mL of DCM.
Amphetamine is a weak base, pKa is 9.9, has a partition coefficient of 50 when distributed between water and benzene. Find the concentration of Amphetamine in each phase when 100 mL of 0.10 M aqueous amphetamine is extracted with 25 mL of benzene at pH 4.00 and pH 10.00.
Solute A has a partition coefficient of 3 between toluene and water, with three times as much in the toluene phase. Suppose that 100 mL of a 0.010M aqueous solution of A is extracted with toluene. What fraction of A remains in the aqueous phase, if five extraction with 100 mL is performed?
1. The partition coefficient, k = (conc. in ligroin/ conc. in water), between ligroin and water for solute A is 6.5. (See Technique 10.1) A) What mass of A would be removed from a solution of 10 grams of A in 100 mL of water by a single extraction with 100 mL of ligroin? B) What mass of A would be removed by four successive extractions of 25-mL portions of ligroin? C) How much ligroin would be required to remove 98.5% of A in a single extraction?
An analyte has a partition coefficient of 6.0 between water and hexane. In order to extract it from 20.0 mL of hexane into water, how much water is needed to extract at least 90% of the analyte all at once?
Assume an organic compound has a partition coefficient between water and ether equal to 7.34. If there are initially 8.67 g of the compound dissolved in 70.0 mL of water, how many grams will remain in the aqueous layer after each extraction with three 15.0 mL portions of ether? mass remaining after the first extraction: mass remaining after the second extraction: mass remaining after the third extraction: g g 5.0 g
(b) A 2.000 g of an organic compound X was dissolved in 50.00 mL of dichloromethane. This organic solution was extracted with 20.00 mL of aqueous solution. Calculate the mass of organic compound, X still remaining in dichloromethane (CH2CI2) after the extraction. The partition coefficient, K(aqueous / dichloromethane) is 1.25.