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- Explain why aspirin is more intestine likely to be absorbed into the bloodstream via the stomach than the small C.In upper gastrointestinal bleeding, without knowing the cause or source of bleeding, why do we give proton pump inhibitors (PPIS, e.g. omeprazole)? What is the role of these, if the source of bleeding is not peptic or duodenal ulcer?Explain how each of the following conditions causes anintestinal obstruction: (1) intussusception; (2) adhesion; (3)inguinal hernia
- A 22-year-old female is experiencing an upset stomach and abdominal pain and has been referred for further testing to visually inspect the gastrointestinal tract to help assist the diagnosis of an inflammatory bowel disease (IBD). Show your understanding by describing the structural changes visible with the two types of inflammatory bowel disease (as viewed via endoscopy or colonoscopy), and include which distinguishing feature of IBD would make the diagnosis definitiveGastric juice acidity is increased in a patient. Answer the questions A and B:A) How and why will the amount and composition of pancreatic juice be changed under these conditions?B) Which receptors are located on the parietal cells and how can they be blocked with aim of normalization gastric juice acidity?When the duodenu is actively digesting food, the Sphincter of Oddi released both bile and pancreatic juice into the duodenum Between meals, when the Sphincter of Oddi is closed, an accessory pancreatic duct remains open, allowing a slow but continual flow of pancreatic juice into the duodenum between meals WHy must there be pancreatic juice in the duodenum even if no food is currently being digested? A- Even if there isnt chyme in the duodenum, stomahc acid might leak into the duodenum. the trypsin in pancreatic juice neutralizes that B- We eat a lot, so we're always digesting food in the duodenum C - the process of fat breakdown is slow, so lipids could stay in the duodenum for over a day, so we need a steady supply of pancreatic lipase. D- Even if there isn't chyme in the duodenum, stomach acid might leak into the duodenum. The bicarbonate in pancreatic juice neutralizes that
- In some severe cases of stomach ulcers, the branches of the vagus nerve (X) that lead to the stomach are surgically severed. How might this procedure control the ulcers?During my clinical rotation in the emergency department, Imet Grace Gilligan. She was a 28-year-old woman who cameto the emergency department with complaints of severeepisodes of nausea and vomiting over the last 48 hours. She has a past medical history of Crohn’s disease, a gastrointes-tinal (GI) problem for which she underwent bowel resection surgery 1 month ago. “I thought the surgery would help myproblems.” The patient was dehydrated and needed IV fluidtherapy.My co-assigned nurse attempted to start a peripheralvenous access not once, but six times. The patient was already upset by her recurrent abdominal symptoms, butnow had to deal with the continuous painful stick of aneedle. During the course of attempts to start the IV, thepatient stated that a nurse on the IV team always had to becalled to insert her IVs. Although my nurse acknowledgedthe information, she continued trying to start the IV. Finally,on the sixth try, as the patient was in tears, the nurse wassuccessful. It…Based on your knowledge of the normal physiology of thestomach, explain why intake of food or milk with a drugreduces the risk of nausea and irritation of the stomach?
- In the clinical setting, one often uses a differential diagnosis. This proccess differentiates between possible diagnoses bases on the person’s symptoms. Here you will demonstrate your knowledge of the gastrointestinal system to either confirm or reject potential diagnosis. A 50-year old, slightly obese individual presents to your clinic with the following symptoms: severe abdominal pain, especially in the left side. However the patient also complains the pain radiates to the right side. They have nausea and have been vomiting for the past several days. Upon examination, you find abdominal tenderness and constipation. The patient is of Asian descent, has been a smoker for the past 20 years, reports frequent alcohol use (>7drinks/week) and takes aspirin on a daily basis (nonsteroidal anti-inflammatory drug). Will age, weight, lifestyle and ethnicity play a role in your diagnosis? Based on the patient’s symptoms, the list of differential diagnoses is extensive as follows: Acute…Inflammation of the digestive tract is common to most irritable bowel diseases including Crohn’s Disease, IBD Syndrome, and Celiac’s Disease. While each of these diseases causes inflammation by a different mechanism, they all result in decreased capacity to absorb nutrients and minerals. In extreme cases, this can lead to severe diarrhea, malnutrition, osteoporosis (weakening of the bones), and iron deficiency, to name a few. Based on the information above, which region(s) and structure(s) of the alimentary canal is (are) most likely targets of inflammation? Explain your answer based on the roles of each segment of the alimentary canal.How could surgical resection of the ileum impact liver function? Consider the intricate interplay between the small intestine and liver in nutrient absorption, bile acid metabolism, and liver function. What are two potential interventions to alleviate the impacts listed above?
