suggest the MIC for the unionised form of the acidic preservative with a pKa of 4.2 is 0.0185mg/mL. What would be the required concentration of preservative to preserve an oral solution that has been buffered to pH 4.7. (Calculate answer as mg/mL and just type the number in to check your answer (not units) The fraction of preservative in the acidic form at a particular pH can be determined using the Henderson-Hasselbach equation:

suggest the MIC for the unionised form of the acidic preservative with a pKa of 4.2 is 0.0185mg/mL. What would be the required concentration of preservative to preserve an oral solution that has been buffered to pH 4.7. (Calculate answer as mg/mL and just type the number in to check your answer (not units) The fraction of preservative in the acidic form at a particular pH can be determined using the Henderson-Hasselbach equation:

Fundamentals Of Analytical Chemistry

9th Edition

ISBN:9781285640686

Author:Skoog

Publisher:Skoog

Chapter14: Principles Of Neutralization Titrations

Section: Chapter Questions

Problem 14.9QAP

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Paragraph BIEE Table 1: pH readings after addition of NaOH to a buffer solution and water Tabel 1: pH metings na byvoeging van NaOH tot die buffer oplossing en water Volume NaOH added Total Volume NaOH added to Volume NaOH bygevoeg Totale Volume NaOH bygevoeg tot pH measurement/ lesing (mL) (mL) Water Buffer Buffer Water 0. 0. 4.6 6.2 5. 5. 4.8 11.4 10 10 4.9 11.7 15 15 4.9 11.9 10 25 25 5.1 12.0 10 35 35 5.4 12.1 20 55 55 6.2 12.2 Path: p » span » strong O555 WIN
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