Table 3: Benzoic Acid and its Metabte Hippuric Acid (Part B) # of H-bond Mol. Wt. # of H-bond (g/mol) donor sites2 acceptor sites3 Benzoic acid Part. Coeff. 17.4 2.2 Log P 1.2 0.32 Hippuric acid 2A H-bond donor site is any H in the molecule that is bonded to a nitrogen or oxygen atom. 3A H-bond acceptor site is any atom that has one or more lone pair(s) of electrons.

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Table 3: Benzoic Acid and its Metabite Hippuric Acid (Part B)
Mol. Wt. # of H-bond
# of H-bond
(g/mol)
donor sites²
acceptor sites3³
Benzoic acid
Part. Coeff.
17.4
2.2
Log P
1.2
0.32
Hippuric acid
2A H-bond donor site is any H in the molecule that is bonded to a nitrogen or oxygen atom.
³A H-bond acceptor site is any atom that has one or more lone pair(s) of electrons.
Transcribed Image Text:Table 3: Benzoic Acid and its Metabite Hippuric Acid (Part B) Mol. Wt. # of H-bond # of H-bond (g/mol) donor sites² acceptor sites3³ Benzoic acid Part. Coeff. 17.4 2.2 Log P 1.2 0.32 Hippuric acid 2A H-bond donor site is any H in the molecule that is bonded to a nitrogen or oxygen atom. ³A H-bond acceptor site is any atom that has one or more lone pair(s) of electrons.
+Table 2: Aspirin and its Metabolites_(Part A)
Mol. Wt.
(g/mol)
Acetylsalicyclic acid
# of H-bond
donor sites²
(see definition below)
X
# of H-bond
acceptor sites³
(see definition below)
Part.
Coeff.
4.6
18.5
Salicylic acid
Gentisic acid
2A H-bond donor site is any H in the molecule that is bonded to a nitrogen or oxygen.
³A H-bond acceptor site is any atom that has one or more lone pair of electrons.
10.0
Log P
0.65
1.2
0.96
Transcribed Image Text:+Table 2: Aspirin and its Metabolites_(Part A) Mol. Wt. (g/mol) Acetylsalicyclic acid # of H-bond donor sites² (see definition below) X # of H-bond acceptor sites³ (see definition below) Part. Coeff. 4.6 18.5 Salicylic acid Gentisic acid 2A H-bond donor site is any H in the molecule that is bonded to a nitrogen or oxygen. ³A H-bond acceptor site is any atom that has one or more lone pair of electrons. 10.0 Log P 0.65 1.2 0.96
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