TABLE 6.2 Concordance of monozygotic and dizygotic twins for several traits Concordance (%) Trait Monozygotic Dizygotic 1. Heart attack (males) 39 26 2. Heart attack (females) 44 14 3. Bronchial asthma 47 24 4. Cancer (all sites) 12 15 5. Epilepsy 59 19 6. Death from acute infection 7.9 8.8 7. Rheumatoid arthritis 32 6 8. Multiple sclerosis 28
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On the basis of the concordances shown in Table is variation in rheumatoid arthritis influenced by genetic factors, environmental factors, or both? Explain your reasoning.
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- A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twins risk decrease if he were raised in an environment different from that of his schizophrenic brother?Why is the chances of having a child with down's syndrome increases if the age of mother exceed forty year?The father of five children begins to show symptoms of huntington disease. what is the probability that same, the man's second oldest son (11-2),, will suffer from the disease if he lives a normal life span? Sam's mother and her ancestors do not have the diseas. Sam's father was adopted, so we do not know his biological family history for hunutington disease. Explore all possible outcome for sam and explain your reasoning
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- Table 7.1: Your genetic traits. Your probable genotype(s) (use only the letter combinations that apply) Your phenotype (list what you look like) Traits (alleles) Almond Straight thumbs 1. Eye shape (R, r) 2. Hitcher's Thumb (H, h) 3. Earlobes (D, d) Free 4. Interlocking Fingers (I, i) Left thumb over right Widows Peak 5. Widow's Peak (F, f) 6. Face Shape (G, g) Oval 7. Eye Color (B, b) Brown 8. Chin Shape (J, j) Round Dimples Brown 9. Dimples (A, a) 10. Hair Color (K, k) Curly 11. Hair Texture (T, t) 12. PTC Taster (Q, q)* Quiz: Quiz 2 A ceu.instructure.com/courses/17293/quizzes/231762/take || 6 10 1. What is the expected Genotype of the grandmother? 2. What is the expected genotype of number 3 given the following offspring in the 3rd generation 3. Who are the persons inherited the Black eyes from the grand mother? Activate Go to Settin Type here to search 31°C Haze 17 110 2 12 IA pri sc delete niten & 3 8. backspac %3D E R YSickle cell anemia is caused by the sickle cell allele (HbS) of a gene that contributes tohemoglobin (Hb) production. The abnormal hemoglobin (hemoglobin-S) produced causes redblood cells to become deformed and block capillaries; tissue damage results. Affected individualshomozygous for the sickle cell gene rarely survive to reproductive age. Heterozygous individualsproduce both normal hemoglobin and a small percentage of hemoglobin-S. These individualsare more resistant to malaria than are individuals who are homozygous for the allele for normalhemoglobin (HbA). Their red blood cells are prone to sickling when there is a deficiency of oxygen. Which of the following conclusions can be drawn from the information provided onsickle cell anemia?a. The sickle cell gene eventually will disappear because of its interaction with malaria.b. Malaria causes heterozygous individuals to be less fertile than homozygous individuals.c. In Africa, sickle cell anemia will disappear because it is lethal…
- Unattached earlobes is dominant to attached earlobes. Two parents, both with unattached earlobes, had a child with attached earlobes. What are the chances that their next child will have attached earlobes? 25% 50% 0% cannot be determined from this infoNeither Tim nor Rhoda has Duchenne muscular dystrophy, but their firstborn son does. What is the probabilitythat a second child will have the disease? What is theprobability if the second child is a boy? A girl?2WGatwill botho estle of grey Sr to white fer In tha offapring? Gg gg GE gg 2:2 which rsduces to 1:1 3. What percentage of the offspring will Tall Short have a tall phenotype? 4. What percentage of the offspring will have a homozygous recessive genotype? TT x tt 5. What percentage of the offspring will have white eyes? White eyes Dark eyes 6. What percentage of the offspring will have a heterozygous genotype? dd x Dd