Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
Table 9.2 shows that DGo’ for the aldolase reaction is large, and positive, yet the reaction proceeds in the forward direction. Using the metabolite concentrations in table 9.3, calculate the actual DG in the cell for the reaction to show that it is consistent with the value reported in table 9.2. Explain in words the strategy the cell uses to keep glycolysis moving in the forward direction (1-2 sentences).

Table 9.2 shows that DGo’ for the aldolase reaction is large, and positive, yet the reaction proceeds in the forward direction. Using the metabolite concentrations in table 9.3, calculate the actual DG in the cell for the reaction to show that it is consistent with the value reported in table 9.2. Explain in words the strategy the cell uses to keep glycolysis moving in the forward direction (1-2 sentences).

Biology (MindTap Course List)
Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter8: How Cells Make Atp: Energy-releasing Pathways
Section: Chapter Questions
Problem 10TYU: Which of the following is a correct ranking of molecules with respect to their energy value in...
See similar textbooks
icon
Related questions
Question

Table 9.2 shows that DGo’ for the aldolase reaction is large, and positive, yet the reaction proceeds in the forward direction. Using the metabolite concentrations in table 9.3, calculate the actual DG in the cell for the reaction to show that it is consistent with the value reported in table 9.2. Explain in words the strategy the cell uses to keep glycolysis moving in the forward direction (1-2 sentences).

Reaction Table 9.2 1. Glucose + ATP → Glucose-6-phosphate + ADP 2. Glucose-6-phosphate → Fructose-6- phosphate 3. Fructose-6-phosphate + ATP → Fructose-1,6- bisphosphate + ADP 4. Fructose-1,6- bisphosphate Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate 5. Dihydroxyacetone phosphate Glyceraldehyde-3-phosphate 6. Glyceraldehyde-3- phosphate + Pi + NAD › 1,3- Bisphosphoglycerate + NADH + H* 8. 3-Phosphoglycerate → 2- Phosphoglycerate 9. 2-Phosphoglycerate Phosphoenolpyruvate + H20 Enzyme 10. Phosphoenolpyruvate + ADP → Pyruvate + ATP Hexokinase Phosphoglucoisomerase Phosphofructokinase-1 Aldolase Glyceraldehyde-3- phosphate dehydrogenase 7. 1,3- Bisphosphoglycerate + ADP → 3- | Phosphoglycerate kinase -18.8 Phosphoglycerate + ATP Phosphoglycerate mutase AGO (kJ/mol) -16.7 Triose phosphate isomerase +7.5 Enolase +1.7 Pyruvate kinase -14.2 +23.8 +6.3 +4.6 +1.7 -31.4
Transcribed Image Text:Reaction Table 9.2 1. Glucose + ATP → Glucose-6-phosphate + ADP 2. Glucose-6-phosphate → Fructose-6- phosphate 3. Fructose-6-phosphate + ATP → Fructose-1,6- bisphosphate + ADP 4. Fructose-1,6- bisphosphate Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate 5. Dihydroxyacetone phosphate Glyceraldehyde-3-phosphate 6. Glyceraldehyde-3- phosphate + Pi + NAD › 1,3- Bisphosphoglycerate + NADH + H* 8. 3-Phosphoglycerate → 2- Phosphoglycerate 9. 2-Phosphoglycerate Phosphoenolpyruvate + H20 Enzyme 10. Phosphoenolpyruvate + ADP → Pyruvate + ATP Hexokinase Phosphoglucoisomerase Phosphofructokinase-1 Aldolase Glyceraldehyde-3- phosphate dehydrogenase 7. 1,3- Bisphosphoglycerate + ADP → 3- | Phosphoglycerate kinase -18.8 Phosphoglycerate + ATP Phosphoglycerate mutase AGO (kJ/mol) -16.7 Triose phosphate isomerase +7.5 Enolase +1.7 Pyruvate kinase -14.2 +23.8 +6.3 +4.6 +1.7 -31.4
Table 9.3 Metabolite Glucose Glucose-6-phosphate 0.083 Fructose-6-phosphate Fructose-1,6-bisphosphate Dihydroxyacetone phosphate Glyceraldehyde-3-phosphate 1,3-Bisphosphoglycerate 3-Phosphoglycerate 2-Phosphoglycerate Phosphoenolpyruvate Pyruvate ATP ADP Pi Concentration (mm) 5 0.083 0.014 0.031 0.138 0.019 0.004 0.118 0.030 0.023 0.051 1.85 0.138 1
Transcribed Image Text:Table 9.3 Metabolite Glucose Glucose-6-phosphate 0.083 Fructose-6-phosphate Fructose-1,6-bisphosphate Dihydroxyacetone phosphate Glyceraldehyde-3-phosphate 1,3-Bisphosphoglycerate 3-Phosphoglycerate 2-Phosphoglycerate Phosphoenolpyruvate Pyruvate ATP ADP Pi Concentration (mm) 5 0.083 0.014 0.031 0.138 0.019 0.004 0.118 0.030 0.023 0.051 1.85 0.138 1
Expert Solution
Step 1

The aldolase reaction is a reversible reaction that occurs in the second stage of glycolysis, converting fructose 1,6-bisphosphate into two triose phosphates, glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The reaction is catalyzed by the enzyme aldolase and is important for breaking down glucose into pyruvate to produce ATP for cellular energy.

steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biology (MindTap Course List)
Biology (MindTap Course List)
Biology
ISBN:
9781337392938
Author:
Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
SEE MORE TEXTBOOKS