The aldol double condensation reaction is highly selective for formation of a single double condensation product. Explain why only one aldol condensation product is formed despite two carbonyl compounds being present for the reaction

Q: What starting materials are needed to synthesize each compound using an aldol or similar reaction?

A: The reactant of a product can be determined by the retrosynthetic method. The retrosynthetic method…

Q: (b) Why is the Claisen-Schmidt reaction a special type of aldol condensation?     one of the…

A: Answers of the above questions given below.

Q: UESTION 4 True or False. The initial prodact of the aldol reaction is a beta-hydroxycarbonyl…

A: A general aldol reaction:

Q: A key step in the synthesis of donepezil is a directed aldol reaction that forms α,β- unsaturated…

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Q: please help Draw the mechanism for the synthesis (Include all the side products and possible…

A: Aldol condensation is a condensation reaction between two carbonyl compounds in which atleast one…

Q: What product results when an aldol product is dehydrated? A) conjugated alkyne B) B-diketone C)…

A: Dehydration is a process in which H2O is leave

Q: Use the retro synthesis to determine the diketone from which the following compounds were formed by…

A: In the intramolecular alodol condenstation reaction nucleophilic attack happen in the same molecule.

Q: Choose the incorrect statements: * a-Aldol is syrupy liquid β-hydroxy aldehyde or β-hydroxy ketone…

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Q: What conditions are necessary for a crossed-aldol reaction to occur? NaOH, H20 H. H. 50° C I II O…

A: In this question, we have to find out the correct answer of given problem by the help of the…

Q: Explain the following reactions giving one example in each : (i) Cross Aldol condensation(ii)…

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Q: The following molecule is formed in a mixed aldol condensation reaction. organic starting materials…

A: As we know , we get beta hydroxy ketone in the aldol condensation reaction. Also condensation is…

Q: Draw the step-by-step mechanisms for the following reactions: a) Step 1 of the aldol condensation OH…

A: Aldol condensation reaction can be defined as the chemical reaction of an enolate ion with the given…

Q: What conditions are necessary for a crossed-aldol reaction to occur? NaOH, H2O H. H. 50° C II O…

A: Concept is based on Aldol reaction

Q: Draw a structural formula for the product of crossed aldol reaction and for the compound formed by…

A: When carbonyl carbons having alpha hydrogens react in the presence of base forms β- hydroxy…

Q: Match the following reagents with the use they have in their respective reactions. A good molecule…

A: Match the following

Q: Why is the Aldol reaction often called an Aldol condensation? O 1) The initially formed b-hydroxy…

A: The question is based on the concept of organic reactions. We have to identify the reason for…

Q: Given the following reaction, how many cross aldol (different starting materials) condensation…

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Q: Draw the structure of the hydroxyaldehyde product from the self-aldol reaction of each of the…

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Q: The product below can be synthesized by a Robinson annulation, which is a Michael addition followed…

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Q: Write the structure for each aldol condensation product that is possible when a mixture of ethanal…

A: In aldol condensation, first enolate will generate. Here ethanal and propanal both can form enolate…

Q: There are other condensation reactions similar to the aldol and Claisen condensations: a. The Perkin…

A: The Perkin condensation is the condensation of an aromatic aldehyde and acetic anhydride. It is…

Q: An aldol addition can be catalyzed by acids as well as by bases. Propose a mechanism for the…

A: Aldol addition reaction: In this reaction two molecules of carbonyl compounds like aldehyde or…

Q: Vanillin has an acidic OH and an electrophilic aldehyde group that could conceivably react with…

A: Vanillin has an acidic OH and an electrophilic aldehyde group that could conceivably react with…

Q: Draw the keto- tautomer for the following enols

A: Tautomers have two form keto form and enol form both keto and enol form are in equilibrium with each…

Q: What is the product resulted due to the reaction of 2-hydroxy-3-methoxybenzaldehyde with ethyl…

A: Basic solution means here base is present in reaction...let base as (B) in reaction... Ethyl bromo…

Q: What is the first step in the acid-catalyzed aldol condensation reaction. Attack of the…

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Q: What aldol product is formed when two molecules of butanal react together in the presence of base?…

A: Treatment of butanal in the presence of strong base forms a resonance-stabilized enolate ion, which…

Q: Draw the step-by-step mechanisms for the following reactions: a) Step 1 of the aldol condensation OH…

A: In an aldol condensation reaction product formed β- hydroxy carbonyl compound then elimination shows…

Q: What starting materials are needed to synthesize each compound using an aldol or similar reaction?

A: Starting materials are needed to synthesize each compound using an aldol or similar reaction are

Q: the product is given predict from what alkene reactant be made from, write the complete reaction on…

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Q: Give the structures of the aldol products that form when each of the following compounds or mixtures…

A: Aldol condensation is the reaction where an enolate reacts with a carbonyl compound to yield a…

Q: need a pushing mechanism for 3,4 dimethoxy-benzaldehyde and 1-indanone in the presence of NaOH. This…

A: First base abstract acidic H+ and nucleophile Attack on benzaldehyde then addition of water gives…

Q: What aldol product is formed when two molecules of butanal react together in the presence of base?…

A: Aldol condensation takes place in only those aldehyde and ketone compounds which possess atleast one…

Q: aldol product aldol product

A: In Aldol condensation reaction, KOH base abstract H+ ion from alpha carbon in Carbonyl Compound and…

Q: Please assist in giving the mechanism of a Claisen Schmidt aldol reaction with 2-methylcyclohexanone…

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Q: In an E1 reaction the solvent acts as a(n) ___________.     reactive intermediate…

A: E1 reaction are favoured by polar protic solvent.

Q: Mixed aldol condensations involving benzaldehyde yield typically a single product. Draw the…

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Q: Review Topics [References] The Robinson annulation is a combination of two carbonyl coupling…

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Q: Draw the product of dehydration of aldol product Q. Butanal

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Q: Which of the following aldehydes does not undergo an aldol condensation when mixed with base?…

A: For any aldehyde to undergo aldol condensation reaction, there should be a alpha H to the C=O group…

Q: Draw the product formed in each directed aldol reaction.

A: Aldol Condensation Reaction: The carbonyl compound having Alpha-hydrogen in the presence of base…

Q: Aldol Mechanisms: Synthesis of 2-ethyl-hex-2-enal

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Q: Part 1 - Draw the full mechanism for the cross-aldol reaction between acetone and benzaldehyde Part…

A: Cross-Aldol condensation This is a variation in aldol-condensation in which two dissimilar carbonyl…

Q: 4-methyl,2-pentanol by aldol comdensation with mechanisam

A: Aldol condensation is a base catalyzed condensation reaction in which two molecules of carbonyl…

Q: Why is the enone product favored to be formed under the shown conditions rather than the aldol…

A: E1cB (Elimination Unimolecular Conjugate base) reaction involves the elimination of poor leaving…

Q: In an aldol condensation reaction, acetone and benzaldehyde are mixed in the presence of sodium…

A: Given: In an aldol condensation reaction, acetone and benzaldehyde are mixed in the presence of…

Q: What is the reaction mechanism for this final step in an Aldol Condensation

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Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.